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In vitro

  • REVIEW
    Experimental models and tools to tackle glioblastoma
    Faye L. Robertson, Maria-Angeles Marqués-Torrejón, Gillian M. Morrison, Steven M. Pollard
    Disease Models & Mechanisms 2019 12: dmm040386 doi: 10.1242/dmm.040386 Published 6 September 2019

    Summary: This Review discusses preclinical modelling of glioblastoma multiforme to understand its biology and develop therapies, with a focus on mammalian model systems.

  • AT A GLANCE
    Disease modelling in human organoids
    Madeline A. Lancaster, Meritxell Huch
    Disease Models & Mechanisms 2019 12: dmm039347 doi: 10.1242/dmm.039347 Published 29 July 2019

    Summary: Human organoids are important tools for modelling disease. This At a Glance article summarises the current organoid models of several human diseases, and discusses future prospects for these technologies.

  • REVIEW
    Cell models of arrhythmogenic cardiomyopathy: advances and opportunities
    Elena Sommariva, Ilaria Stadiotti, Gianluca L. Perrucci, Claudio Tondo, Giulio Pompilio
    Disease Models & Mechanisms 2017 10: 823-835; doi: 10.1242/dmm.029363

    Summary: In vitro models of ACM provide insights into the molecular mechanisms of this disease. This reappraisal offers a comprehensive vision of past discoveries and constitutes a tool for future research.

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