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Valproic acid

  • RESEARCH ARTICLE
    Diacylglycerol kinase (DGKA) regulates the effect of the epilepsy and bipolar disorder treatment valproic acid in Dictyostelium discoideum
    Elizabeth Kelly, Devdutt Sharma, Christopher J. Wilkinson, Robin S. B. Williams
    Disease Models & Mechanisms 2018 11: dmm035600 doi: 10.1242/dmm.035600 Published 21 August 2018

    Editor's choice: Here, using a tractable model system, Dictyostelium discoideum, we show that diacylglycerol kinase activity might contribute to the cellular mechanism of action of the epilepsy and bipolar disorder treatment, valproic acid.

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