supporting biologists inspiring biology

Disease Models & Mechanisms

Survival motor neuron

REVIEW

Therapeutic strategies for spinal muscular atrophy: SMN and beyond
Melissa Bowerman, Catherina G. Becker, Rafael J. Yáñez-Muñoz, Ke Ning, Matthew J. A. Wood, Thomas H. Gillingwater, Kevin Talbot, The UK SMA Research Consortium

Disease Models & Mechanisms 2017 10: 943-954; doi: 10.1242/dmm.030148

Summary: Translational research for spinal muscular atrophy (SMA) should address the development of non-CNS and survival motor neuron (SMN)-independent therapeutic approaches to complement and enhance the benefits of CNS-directed and SMN-dependent therapies.