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Disease Models & Mechanisms

Pericyte

RESEARCH ARTICLE

Choroidal pericytes promote subretinal fibrosis after experimental photocoagulation
Xueting Luo, Shiqi Yang, Jian Liang, Yuanqi Zhai, Mengxi Shen, Junran Sun, Yiji Feng, Xinmin Lu, Hong Zhu, Fenghua Wang, Xiaodong Sun

Disease Models & Mechanisms 2018 11: dmm032060 doi: 10.1242/dmm.032060 Published 23 April 2018

Summary: Using a laser-induced photocoagulation model with collagen 1α1-GFP reporter mice, we identified choroidal pericytes as potential therapeutic targets to prevent subretinal fibrosis for management of neovascular age-related macular degeneration.