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Peptide therapeutic

  • RESEARCH ARTICLE
    A Drosophila model of oral peptide therapeutics for adult intestinal stem cell tumors
    Anjali Bajpai, Taushif Ahmad Quazi, Hong-Wen Tang, Nishat Manzar, Virender Singh, Ashwani Thakur, Bushra Ateeq, Norbert Perrimon, Pradip Sinha
    Disease Models & Mechanisms 2020 13: dmm044420 doi: 10.1242/dmm.044420 Published 23 July 2020

    Summary: We demonstrate that, when fed to flies, TONDU peptide suppresses Yki-driven intestinal stem cell (ISC) tumors, and identify integrins as essential components of ISC tumorigenesis.

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