MicroRNA
- Circulating exosomal microRNAs as potential biomarkers of hepatic injury and inflammation in a murine model of glycogen storage disease type 1a
Summary: Mice with glycogen storage disease type 1a (GSD1a) show altered expression of several microRNAs, correlated with various pathologic liver states. This might help us to understand the progression of the disease and the development of late GSD1a-associated complications.
- Overexpression of microRNA-722 fine-tunes neutrophilic inflammation by inhibiting Rac2 in zebrafish
Summary: Identification of a microRNA that suppresses Rac2 expression and regulates neutrophil migration and systemic inflammation. This article has an associated First Person interview with the first author of the paper as part of the supplementary information.
- MicroRNAs in the etiology of colorectal cancer: pathways and clinical implications
Summary: This Review provides an overview of some important microRNAs and their roles in colorectal cancer.
- MicroRNA screening identifies a link between NOVA1 expression and a low level of IKAP in familial dysautonomia
Summary: A miRNA screening conducted in olfactory stem cells from patients links the neuron-specific splicing factor NOVA1 to neurodegeneration in familial dysautonomia.
- MicroRNA-16 suppresses metastasis in an orthotopic, but not autochthonous, mouse model of soft tissue sarcoma
Summary: This work underscores the importance of studying cancer metastasis using in vivo model systems in addition to in vitro and transplant model systems.