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Disease Models & Mechanisms

Memory

RESEARCH ARTICLE

Individual components of the SWI/SNF chromatin remodelling complex have distinct roles in memory neurons of the Drosophila mushroom body
Melissa C. Chubak, Kevin C. J. Nixon, Max H. Stone, Nicholas Raun, Shelby L. Rice, Mohammed Sarikahya, Spencer G. Jones, Taylor A. Lyons, Taryn E. Jakub, Roslyn L. M. Mainland, Maria J. Knip, Tara N. Edwards, Jamie M. Kramer

Disease Models & Mechanisms 2019 12: dmm037325 doi: 10.1242/dmm.037325 Published 25 March 2019

Summary: The SWI/SNF chromatin remodelling complex is the most over-represented protein complex in the intellectual disability. Different components of this complex have distinct roles in development and function of memory-forming neurons in the Drosophila mushroom body.
RESEARCH ARTICLE

Nicotine ameliorates schizophrenia-like cognitive deficits induced by maternal LPS exposure: a study in rats
Uta Waterhouse, Vic E. Roper, Katharine A. Brennan, Bart A. Ellenbroek

Disease Models & Mechanisms 2016 9: 1159-1167; doi: 10.1242/dmm.025072

Summary: This is the first pharmacological study examining the effect of repeated nicotine treatment on multiple schizophrenia-like cognitive deficits induced by maternal exposure to an infectious agent (LPS) in rats.