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Lysosomal enzymes

  • REVIEW
    Induced pluripotent stem cell models of lysosomal storage disorders
    Daniel K. Borger, Benjamin McMahon, Tamanna Roshan Lal, Jenny Serra-Vinardell, Elma Aflaki, Ellen Sidransky
    Disease Models & Mechanisms 2017 10: 691-704; doi: 10.1242/dmm.029009

    Summary: This Review discusses how induced pluripotent stem cells (iPSCs) provide new opportunities to explore the biology and pathophysiology of lysosomal storage diseases, and how iPSCs have illuminated the role of lysosomes in more common disorders.

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