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Growth

  • RESEARCH ARTICLE
    A comparison of the bone and growth phenotype of mdx, mdx:Cmah−/− and mdx:Utrn+/− murine models with the C57BL/10 wild-type mouse
    Claire L. Wood, Karla J. Suchacki, Rob van ’t Hof, Will P. Cawthorn, Scott Dillon, Volker Straub, Sze Choong Wong, Syed F. Ahmed, Colin Farquharson
    Disease Models & Mechanisms 2020 13: dmm040659 doi: 10.1242/dmm.040659 Published 10 January 2020

    Editors' choice: Unlike boys with DMD, the mdx:Cmah−/− mouse shows increased weight gain and more rapid bone development; therefore, its utility for studying growth and skeletal development in DMD is limited.

  • RESEARCH ARTICLE
    Chronic psychosocial stress disturbs long-bone growth in adolescent mice
    Sandra Foertsch, Melanie Haffner-Luntzer, Jochen Kroner, Florian Gross, Kathrin Kaiser, Maike Erber, Stefan O. Reber, Anita Ignatius
    Disease Models & Mechanisms 2017 10: 1399-1409; doi: 10.1242/dmm.030916

    Summary: Chronic psychosocial stress is a known risk factor for many somatic disorders. The authors demonstrate that chronic psychosocial stress negatively affects endochondral ossification in the growth plate, as well as long-bone growth. This article has an associated First Person interview with the first author of the paper as part of the supplementary information.

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