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Disease Models & Mechanisms

Granuloma formation

RESEARCH ARTICLE

Cx3cr1 deficiency in mice attenuates hepatic granuloma formation during acute schistosomiasis by enhancing the M2-type polarization of macrophages
Lin Ran, Qilin Yu, Shu Zhang, Fei Xiong, Jia Cheng, Ping Yang, Jun-Fa Xu, Hao Nie, Qin Zhong, Xueli Yang, Fei Yang, Quan Gong, Michal Kuczma, Piotr Kraj, Weikuan Gu, Bo-Xu Ren, Cong-Yi Wang

Disease Models & Mechanisms 2015 8: 691-700; doi: 10.1242/dmm.018242

Highlighted Article: A reduction in CX3CR1 signaling provides protection for mice against pro-inflammatory responses and hepatic granuloma formation during acute schistosomiasis.