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Genetic screen

  • RESOURCE ARTICLE
    Early-onset torsion dystonia: a novel high-throughput yeast genetic screen for factors modifying protein levels of torsinAΔE
    Lucía F. Zacchi, John C. Dittmar, Michael J. Mihalevic, Annette M. Shewan, Benjamin L. Schulz, Jeffrey L. Brodsky, Kara A. Bernstein
    Disease Models & Mechanisms 2017 10: 1129-1140; doi: 10.1242/dmm.029926

    Summary: A novel high-throughput, automated, genome-wide yeast screen was used to identify genetic modifiers of the steady-state levels of proteins of the dystonia-associated torsinAΔE variant. This article has an associated First Person interview with the first author of the paper as part of the supplementary information.

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