eQTL
- Conserved properties of genetic architecture of renal and fat transcriptomes in rat models of insulin resistance
Summary: Kidney and fat expression QTL mapping in rat models of spontaneously occurring insulin resistance associated with either diabetes or hypertension reveals conserved gene expression regulation, suggesting shared aetiology of disease phenotypes.
- From integrative genomics to systems genetics in the rat to link genotypes to phenotypes
Summary: This Review describes the most recent advances in the field of systems genetics, focusing on the rat. We cover from the first integrative genomics strategies (such as mapping of expression QTLs or eQTLs) and conclude with the most sophisticated gene network-based analyses in multiple systems and disease states.