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Catecholamines

  • RESEARCH ARTICLE
    Heterozygous disruption of activin receptor-like kinase 1 is associated with increased arterial pressure in mice
    María González-Núñez, Adela S. Riolobos, Orlando Castellano, Isabel Fuentes-Calvo, María de los Ángeles Sevilla, Bárbara Oujo, Miguel Pericacho, Ignacio Cruz-Gonzalez, Fernando Pérez-Barriocanal, Peter ten Dijke, Jose M. López-Novoa
    Disease Models & Mechanisms 2015 8: 1427-1439; doi: 10.1242/dmm.019695

    Summary: Mice haploinsufficient for Alk1, a receptor for the TGF-β family, show hypertension, based on overactivation of the sympathetic nervous system and a reduction in the number of cholinergic neurons in the CNS.

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