Anaemia
- Bone marrow transplantation corrects haemolytic anaemia in a novel ENU mutagenesis mouse model of TPI deficiency
Summary: In a novel ENU mutagenesis mouse model of TPI deficiency, bone marrow transplantation was conducted to demonstrate that haemolytic and red blood cell glycolytic defects can be effectively rescued.
- A mouse model of hereditary coproporphyria identified in an ENU mutagenesis screen
Summary: A mouse mutagenesis model of hereditary coproporphyria has significant genetic and biochemical parallels to that of the human condition.