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Acinar cells

  • RESEARCH ARTICLE
    A novel pancreatic cancer model originated from transformation of acinar cells in adult tree shrew, a primate-like animal
    Qiu Tu, Dong Yang, Xianning Zhang, Xintong Jia, Sanqi An, Lanzhen Yan, Hongjuan Dai, Yuhua Ma, Chengwei Tang, Weimin Tong, Zongliu Hou, Longbao Lv, Jing Tan, Xudong Zhao
    Disease Models & Mechanisms 2019 12: dmm038703 doi: 10.1242/dmm.038703 Published 15 April 2019

    Summary: Our work identified the driver mutations indispensable for PDAC induction from acinar cells in mature adults and established a novel PDAC animal model with increased similarity to human disease.

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