Table 2.

FA or inositol supplementation increases the percentage of normal heart development

HH stageTreatment*Number of embryosAbnormal embryosNormal embryosNormal hearts (%)
3+/4Control (NaCl)87454248%
3+/4HCy1281002822%
3+/4HCy + FA57263154%
5Control (NaCl)42113174%
5HCy74502432%
5HCy + FA2261673%
3+/4FA only115655%
3+/4Inositol only52360%
3+/4Li only2921828%
3+/4Li + FA40211948%
3+/4Li + inositol30181240%
3+/4Li + FA + inositol3492574%
  • * Concentrations used: HCy, 50 μM; Li, 50 μM; FA, 10 μM; inositol, 50 mM.