Table 1.

Number of animals exhibiting each type of epileptiform activity at 6 and 9 weeks of age

GenotypeTreatmentAge (wks)nSpikesRepetitive spikes (<5 seconds)Repetitive spike runs (>5–<10 seconds)Seizures (>10 seconds)
Wild typeNaïve660 (0)0 (0)0 (0)0 (0)
MutantNaïve677 (100)7 (100)7 (100)7 (100)
MutantVehicle699 (100)9 (100)9 (100)9 (100)
MutantRapamycin677 (100)6 (85.7)2 (28.6)3 (42.9)
Wild typeNaïve960 (0)0 (0)0 (0)0 (0)
MutantNaïve977 (100)7 (100)7 (100)7 (100)
MutantVehicle988 (100)8 (100)8 (100)8 (100)
MutantRapamycin977 (100)5 (71.4)2 (28.6)1 (14.3)
  • Percentage of animals is given in parentheses.