Table 1

Genotypes obtained from either Hesx1I26T/+ or Hesx1R160C/+ intercrosses

StageGenotype
Hesx1I26T/+Hesx1+/+Hesx1I26T/I26THesx1R160C/+Hesx1+/+Hesx1R160C/R160C
Pups124 (∼46%)97 (∼36%)*50 (∼18%)94 (∼64%)47 (∼32%)5 (∼3%)
8.5 dpc2417101587
10.5 dpc9351346
12.5 dpc341316321015
15.5 dpc2111821810
17.5 dpc241413421818
Embryos total§112 (∼50%)58 (26%)52 (23%)123 (∼54%)48 (∼21%)56 (∼25%)
  • *Chi-square test showed a signi3cant deviation from the expected 25% ratio (P<0.03).

  • Chi-square test showed no signi3cant deviation from the expected 25% ratio.

  • Chi-square test showed a signi3cant deviation from the expected 25% ratio (P<0.001).

  • §Chi-square test showed no signi3cant deviation from the expected Mendelian ratios.