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Accepted manuscripts

Accepted manuscripts are peer-reviewed author manuscripts posted online in manuscript form soon after article acceptance and in advance of publication of the online issues in which they will appear. Each article is subsequently enhanced by in-house scientific copyediting of text and figures, proofreading, typesetting and article layout, and will be published in printable PDF format, with a fully linked full-text version.  

To receive an email alert when new Accepted manuscripts are posted, click here

More information, including how to cite Accepted manuscripts, can be found here.

January 11, 2021

  • Accepted Manuscript
    RESEARCH ARTICLE
    Open Access
    Neural crest-specific deletion of Bmp7 leads to midfacial hypoplasia, nasal airway obstruction, and disordered breathing modelling Obstructive Sleep Apnea
    Pranidhi Baddam, Vivian Biancardi, Daniela M. Roth, Farah Eaton, Claudine Thereza-Bussolaro, Rupasri Mandal, David S. Wishart, Amy Barr, Joanna MacLean, Carlos Flores-Mir, Silvia Pagliardini, Daniel Graf
    Disease Models & Mechanisms 2021 : doi: 10.1242/dmm.047738
  • Accepted Manuscript
    RESEARCH ARTICLE
    Open Access
    Inducible expression of human C9ORF72 36x G4C2 hexanucleotide repeats is sufficient to cause RAN translation and rapid muscular atrophy in mice
    F. W. Riemslagh, E. C. van der Toorn, R. F. M. Verhagen, A. Maas, L. W. J. Bosman, R. K. Hukema, R. Willemsen
    Disease Models & Mechanisms 2021 : doi: 10.1242/dmm.044842

January 06, 2021

  • Accepted Manuscript
    RESEARCH ARTICLE
    Open Access
    TDP-43 mislocalization drives neurofilament changes in a novel model of TDP-43 proteinopathy
    Rachel Atkinson, Jacqueline Leung, James Bender, Matthew Kirkcaldie, James Vickers, Anna King
    Disease Models & Mechanisms 2021 : doi: 10.1242/dmm.047548
  • Accepted Manuscript
    RESEARCH ARTICLE
    Open Access
    A muscle growth promoting treatment based on the attenuation of activin/myostatin signalling in young mice results in long-term testicular abnormalities
    Danielle Vaughan, Robert Mitchell, Oliver Kretz, David Chambers, Maciej Lalowski, Helge Amthor, Olli Ritvos, Arja Pasternack, Antonios Matsakas, Sakthivel Vaiyapuri, Tobias B. Huber, Bernd Denecke, Abir Mukherjee, Darius Widera, Ketan Patel
    Disease Models & Mechanisms 2021 : doi: 10.1242/dmm.047555

January 04, 2021

  • Accepted Manuscript
    RESEARCH ARTICLE
    Open Access
    Interpreting the pathogenicity of Joubert Syndrome missense variants in Caenorhabditis elegans
    Karen I. Lange, Sofia Tsiropoulou, Katarzyna Kucharska, Oliver E. Blacque
    Disease Models & Mechanisms 2020 : doi: 10.1242/dmm.046631

December 29, 2020

  • Accepted Manuscript
    RESEARCH ARTICLE
    Open Access
    Mistargeting of secretory cargo in retromer-deficient cells
    Sarah D. Neuman, Erica L. Terry, Jane E. Selegue, Amy T. Cavanagh, Arash Bashirullah
    Disease Models & Mechanisms 2020 : doi: 10.1242/dmm.046417

December 16, 2020

  • Accepted Manuscript
    RESEARCH ARTICLE
    Open Access
    Disruption of a hedgehog-foxf1-rspo2 signaling axis leads to tracheomalacia and a loss of sox9+ tracheal chondrocytes
    Talia Nasr, Andrea M. Holderbaum, Praneet Chaturvedi, Kunal Agarwal, Jessica L. Kinney, Keziah Daniels, Stephen L. Trisno, Vladimir Ustiyan, John M. Shannon, James M. Wells, Debora Sinner, Vladimir V. Kalinichenko, Aaron M. Zorn
    Disease Models & Mechanisms 2020 : doi: 10.1242/dmm.046573

December 14, 2020

  • Accepted Manuscript
    RESEARCH ARTICLE
    Open Access
    Hearing impairment due to Mir183/96/182 mutations suggests both loss and gain of function effects
    Morag A. Lewis, Francesca Di Domenico, Neil J. Ingham, Haydn M. Prosser, Karen P. Steel
    Disease Models & Mechanisms 2020 : doi: 10.1242/dmm.047225
  • Accepted Manuscript
    RESEARCH ARTICLE
    Open Access
    RET inhibition in novel patient-derived models of RET-fusion positive lung adenocarcinoma reveals a role for MYC upregulation
    Takuo Hayashi, Igor Odintsov, Roger S. Smith, Kota Ishizawa, Allan J. W. Liu, Lukas Delasos, Christopher Kurzatkowski, Huichun Tai, Eric Gladstone, Morana Vojnic, Shinji Kohsaka, Ken Suzawa, Zebing Liu, Siddharth Kunte, Marissa S. Mattar, Inna Khodos, Monika A. Davare, Alexander Drilon, Emily Cheng, Elisa de Stanchina, Marc Ladanyi, Romel Somwar
    Disease Models & Mechanisms 2020 : doi: 10.1242/dmm.047779

December 08, 2020

  • Accepted Manuscript
    RESEARCH ARTICLE
    Open Access
    Head to head study of oxelumab and adalimumab in a mouse model of ulcerative colitis based on NOD/Scid IL-2Rγnull mice reconstituted with peripheral blood mononuclear cells
    Henrika Jodeleit, Paula Winkelmann, Janina Caesar, Sebastian Sterz, Lesca M. Holdt, Florian Beigel, Johannes Stallhofer, Simone Breiteneicher, Eckart Bartnik, Thomas Leeuw, Matthias Siebeck, Roswitha Gropp
    Disease Models & Mechanisms 2020 : doi: 10.1242/dmm.046995

December 01, 2020

  • Accepted Manuscript
    RESEARCH ARTICLE
    Open Access
    Sensory neuron cultures derived from adult db/db mice as a simplified model to study type-2 diabetes-associated axonal regeneration defects
    Cristian De Gregorio, Fernando Ezquer
    Disease Models & Mechanisms 2020 : doi: 10.1242/dmm.046334

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