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Disease Models & Mechanisms

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Establishment and validation of an endoplasmic reticulum stress reporter to monitor zebrafish ATF6 activity in development and disease
Eric M. Clark, Hannah J. T. Nonarath, Jonathan R. Bostrom, Brian A. Link

Disease Models & Mechanisms Jan 2019, dmm.041426; DOI: 10.1242/dmm.041426
A novel patient-derived orthotopic xenograft model of esophageal adenocarcinoma provides a platform for translational discoveries
Omkara Lakshmi Veeranki, Zhimin Tong, Alicia Mejia, Anuj Verma, Riham Katkhuda, Roland Bassett, Tae-Beom Kim, Jing Wang, Wenhua Lang, Barbara Mino, Luisa Solis, Charles Kingsley, William Norton, Ramesh Tailor, Ji Yuan Wu, Sunil Krishnan, Steven H. Lin, Mariela Blum, Wayne Hofstetter, Jaffer Ajani, Scott Kopetz, Dipen Maru

Disease Models & Mechanisms Dec 2019, 12 (12) dmm041004; DOI: 10.1242/dmm.041004
SILAC-based quantitative proteomics using mass spectrometry quantifies endoplasmic reticulum stress in whole HeLa cells
Daniel N. Itzhak, Francesca Sacco, Nagarjuna Nagaraj, Stefka Tyanova, Matthias Mann, Marta Murgia

Disease Models & Mechanisms Nov 2019, 12 (11) dmm040741; DOI: 10.1242/dmm.040741
Deep learning enables automated volumetric assessments of cardiac function in zebrafish
Alexander A. Akerberg, Caroline E. Burns, C. Geoffrey Burns, Christopher Nguyen

Disease Models & Mechanisms Oct 2019, 12 (10) dmm040188; DOI: 10.1242/dmm.040188
Characterization of acute TLR-7 agonist-induced hemorrhagic myocarditis in mice by multiparametric quantitative cardiac magnetic resonance imaging
Nicoleta Baxan, Angelos Papanikolaou, Isabelle Salles-Crawley, Amrit Lota, Rasheda Chowdhury, Olivier Dubois, Jane Branca, Muneer G. Hasham, Nadia Rosenthal, Sanjay K. Prasad, Lan Zhao, Sian E. Harding, Susanne Sattler

Disease Models & Mechanisms Aug 2019, 12 (8) dmm040725; DOI: 10.1242/dmm.040725
Genome-wide analysis of androgen receptor binding and transcriptomic analysis in mesenchymal subsets during prostate development
Claire Nash, Nadia Boufaied, Dunarel Badescu, Yu Chang Wang, Miltiadis Paliouras, Mark Trifiro, Ioannis Ragoussis, Axel A. Thomson

Disease Models & Mechanisms Jul 2019, 12 (7) dmm039297; DOI: 10.1242/dmm.039297
Standardised imaging pipeline for phenotyping mouse laterality defects and associated heart malformations, at multiple scales and multiple stages
Audrey Desgrange, Johanna Lokmer, Carmen Marchiol, Lucile Houyel, Sigolène M. Meilhac

Disease Models & Mechanisms Jul 2019, 12 (7) dmm038356; DOI: 10.1242/dmm.038356
Sensitive bioluminescence imaging of fungal dissemination to the brain in mouse models of cryptococcosis
Liesbeth Vanherp, Alexandra Ristani, Jennifer Poelmans, Amy Hillen, Katrien Lagrou, Guilhem Janbon, Matthias Brock, Uwe Himmelreich, Greetje Vande Velde

Disease Models & Mechanisms Jun 2019, 12 (6) dmm039123; DOI: 10.1242/dmm.039123
CRISPR/Cas9-generated mouse model of Duchenne muscular dystrophy recapitulating a newly identified large 430 kb deletion in the human DMD gene
Tatiana V. Egorova, Evgenia D. Zotova, Denis A. Reshetov, Anna V. Polikarpova, Svetlana G. Vassilieva, Dmitry V. Vlodavets, Alexey A. Gavrilov, Sergey V. Ulianov, Vladimir L. Buchman, Alexei V. Deykin

Disease Models & Mechanisms Apr 2019, 12 (4) dmm037655; DOI: 10.1242/dmm.037655
Recapitulating Parkinson's disease pathology in a three-dimensional human neural cell culture model
Teresa R. Taylor-Whiteley, Christine L. Le Maitre, James A. Duce, Caroline F. Dalton, David P. Smith

Disease Models & Mechanisms Apr 2019, 12 (4) dmm038042; DOI: 10.1242/dmm.038042

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