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Disease Models & Mechanisms

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Regulation of copper homeostasis by members of the COMMD protein family
Amika Singla, Qing Chen, Kohei Suzuki, Jie Song, Alina Fedoseienko, Melinde Wijers, Adam Lopez, Daniel D. Billadeau, Bart van de Sluis, Ezra Burstein

Disease Models & Mechanisms Jan 2020, dmm.045963; DOI: 10.1242/dmm.045963
Accepted Manuscript
Sensory neuron cultures derived from adult db/db mice as a simplified model to study type-2 diabetes-associated axonal regeneration defects
Cristian De Gregorio, Fernando Ezquer

Disease Models & Mechanisms Jan 2020, dmm.046334; DOI: 10.1242/dmm.046334
Akkermansia muciniphila promotes type H vessel formation and bone fracture healing by reducing gut permeability and inflammation
Jiang-Hua Liu, Tao Yue, Zhong-Wei Luo, Jia Cao, Zi-Qi Yan, Ling Jin, Teng-Fei Wan, Ci-Jun Shuai, Zheng-Guang Wang, Yong Zhou, Ran Xu, Hui Xie

Disease Models & Mechanisms Nov 2020, 13 (11) dmm043620; DOI: 10.1242/dmm.043620
Teleological role of L-2-hydroxyglutarate dehydrogenase in the kidney
Garrett Brinkley, Hyeyoung Nam, Eunhee Shim, Richard Kirkman, Anirban Kundu, Suman Karki, Yasaman Heidarian, Jason M. Tennessen, Juan Liu, Jason W. Locasale, Tao Guo, Shi Wei, Jennifer Gordetsky, Teresa L. Johnson-Pais, Devin Absher, Dinesh Rakheja, Anil K. Challa, Sunil Sudarshan

Disease Models & Mechanisms Nov 2020, 13 (11) dmm045898; DOI: 10.1242/dmm.045898
Using systems medicine to identify a therapeutic agent with potential for repurposing in inflammatory bowel disease
Katie Lloyd, Stamatia Papoutsopoulou, Emily Smith, Philip Stegmaier, Francois Bergey, Lorna Morris, Madeleine Kittner, Hazel England, Dave Spiller, Mike H. R. White, Carrie A. Duckworth, Barry J. Campbell, Vladimir Poroikov, Vitor A. P. Martins dos Santos, Alexander Kel, Werner Muller, D. Mark Pritchard, Chris Probert, Michael D. Burkitt, The SysmedIBD Consortium

Disease Models & Mechanisms Nov 2020, 13 (11) dmm044040; DOI: 10.1242/dmm.044040
Restoration of motor learning in a mouse model of Rett syndrome following long-term treatment with a novel small-molecule activator of TrkB
Ian Adams, Tao Yang, Frank M. Longo, David M. Katz

Disease Models & Mechanisms Nov 2020, 13 (11) dmm044685; DOI: 10.1242/dmm.044685
L-type voltage-gated calcium channel agonists mitigate hearing loss and modify ribbon synapse morphology in the zebrafish model of Usher syndrome type 1
Alaa Koleilat, Joseph A. Dugdale, Trace A. Christenson, Jeffrey L. Bellah, Aaron M. Lambert, Mark A. Masino, Stephen C. Ekker, Lisa A. Schimmenti

Disease Models & Mechanisms Nov 2020, 13 (11) dmm043885; DOI: 10.1242/dmm.043885
Accepted Manuscript
Interpreting the pathogenicity of Joubert Syndrome missense variants in Caenorhabditis elegans
Karen I. Lange, Sofia Tsiropoulou, Katarzyna Kucharska, Oliver E. Blacque

Disease Models & Mechanisms Jan 2020, dmm.046631; DOI: 10.1242/dmm.046631
Accepted Manuscript
Impaired muscle morphology in a Drosophila model of myosin storage myopathy was supressed by overexpression of an E3 ubiquitin ligase
Martin Dahl-Halvarsson, Montse Olive, Malgorzata Pokrzywa, Michaela Norum, Katarina Ejeskär, Homa Tajsharghi

Disease Models & Mechanisms Jan 2020, dmm.047886; DOI: 10.1242/dmm.047886
Differential physiological roles for BIN1 isoforms in skeletal muscle development, function and regeneration
Ivana Prokic, Belinda S. Cowling, Candice Kutchukian, Christine Kretz, Hichem Tasfaout, Vincent Gache, Josiane Hergueux, Olivia Wendling, Arnaud Ferry, Anne Toussaint, Christos Gavriilidis, Vasugi Nattarayan, Catherine Koch, Jeanne Lainé, Roy Combe, Laurent Tiret, Vincent Jacquemond, Fanny Pilot-Storck, Jocelyn Laporte

Disease Models & Mechanisms Nov 2020, 13 (11) dmm044354; DOI: 10.1242/dmm.044354

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Disease Models & Mechanisms

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