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Disease Models & Mechanisms

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Accepted Manuscript
Perturbation of the titin/MURF1 signaling complex is associated with hypertrophic cardiomyopathy in a fish model and in human patients
Yuta Higashikuse, Nishant Mittal, Takuro Arimura, Sung Han Yoon, Mayumi Oda, Hirokazu Enomoto, Ruri Kaneda, Fumiyuki Hattori, Takeshi Suzuki, Atsushi Kawakami, Alexander Gasch, Tetsushi Furukawa, Siegfried Labeit, Keiichi Fukuda, Akinori Kimura, Shinji Makino

Disease Models & Mechanisms Jan 2019, dmm.041103; DOI: 10.1242/dmm.041103
Accepted Manuscript
Novel mouse model of encephalocele: post-neurulation origin and relationship to open neural tube defects
Ana Rolo, Gabriel L. Galea, Dawn Savery, Nicholas D. E. Greene, Andrew J. Copp

Disease Models & Mechanisms Jan 2019, dmm.040683; DOI: 10.1242/dmm.040683
Inducible SMARCAL1 knockdown in iPSC reveals a link between replication stress and altered expression of master differentiation genes
Giusj Monia Pugliese, Federico Salaris, Valentina Palermo, Veronica Marabitti, Nicolò Morina, Alessandro Rosa, Annapaola Franchitto, Pietro Pichierri

Disease Models & Mechanisms Oct 2019, 12 (10) dmm039487; DOI: 10.1242/dmm.039487
Reversion of tumor hepatocytes to normal hepatocytes during liver tumor regression in an oncogene-expressing transgenic zebrafish model
Yan Li, Ira Agrawal, Zhiyuan Gong

Disease Models & Mechanisms Oct 2019, 12 (10) dmm039578; DOI: 10.1242/dmm.039578
mTOR hyperactivity mediates lysosomal dysfunction in Gaucher's disease iPSC-neuronal cells
Robert A. Brown, Antanina Voit, Manasa P. Srikanth, Julia A. Thayer, Tami J. Kingsbury, Marlene A. Jacobson, Marta M. Lipinski, Ricardo A. Feldman, Ola Awad

Disease Models & Mechanisms Oct 2019, 12 (10) dmm038596; DOI: 10.1242/dmm.038596
Accepted Manuscript
Harnessing region-specific neurovascular signaling to promote germinal matrix vessel maturation and hemorrhage prevention
Devi Santhosh, Joe Sherman, Shafi Chowdhury, Zhen Huang

Disease Models & Mechanisms Jan 2019, dmm.041228; DOI: 10.1242/dmm.041228
A small bioactive glycoside inhibits epsilon toxin and prevents cell death
Abhishek Shivappagowdar, Soumya Pati, Chintam Narayana, Rajagopal Ayana, Himani Kaushik, Raj Sah, Swati Garg, Ashish Khanna, Jyoti Kumari, Lalit Garg, Ram Sagar, Shailja Singh

Disease Models & Mechanisms Oct 2019, 12 (10) dmm040410; DOI: 10.1242/dmm.040410
Accepted Manuscript
Temporal evolution of the microbiome, immune system, and epigenome with disease progression in ALS mice
Claudia Figueroa-Romero, Kai Guo, Benjamin J. Murdock, Ximena Paez-Colasante, Christine M. Bassis, Kristen A. Mikhail, Kristen D. Raue, Matthew C. Evans, Ghislaine F. Taubman, Andrew J. McDermott, Phillipe D. O'Brien, Masha G. Savelieff, Junguk Hur, Eva L. Feldman

Disease Models & Mechanisms Jan 2019, dmm.041947; DOI: 10.1242/dmm.041947
Spz/Toll-6 signal guides organotropic metastasis in Drosophila
Ketu Mishra-Gorur, Daming Li, Xianjue Ma, Yanki Yarman, Lei Xue, Tian Xu

Disease Models & Mechanisms Oct 2019, 12 (10) dmm039727; DOI: 10.1242/dmm.039727
Perturbed development of cranial neural crest cells in association with reduced sonic hedgehog signaling underlies the pathogenesis of retinoic-acid-induced cleft palate
Qi Wang, Hiroshi Kurosaka, Masataka Kikuchi, Akihiro Nakaya, Paul A. Trainor, Takashi Yamashiro

Disease Models & Mechanisms Oct 2019, 12 (10) dmm040279; DOI: 10.1242/dmm.040279

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Disease Models & Mechanisms

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