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Disease Models & Mechanisms

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Long-term drug administration in the adult zebrafish using oral gavage for cancer preclinical studies
Michelle Dang, Rachel E. Henderson, Levi A. Garraway, Leonard I. Zon

Disease Models & Mechanisms Jul 2016, 9 (7) 811-820; DOI: 10.1242/dmm.024166
Decreased N-TAF1 expression in X-linked dystonia-parkinsonism patient-specific neural stem cells
Naoto Ito, William T. Hendriks, Jyotsna Dhakal, Christine A. Vaine, Christina Liu, David Shin, Kyle Shin, Noriko Wakabayashi-Ito, Marisela Dy, Trisha Multhaupt-Buell, Nutan Sharma, Xandra O. Breakefield, D. Cristopher Bragg

Disease Models & Mechanisms Apr 2016, 9 (4) 451-462; DOI: 10.1242/dmm.022590
Multimodal analysis of ocular inflammation using the endotoxin-induced uveitis mouse model
Colin J. Chu, Peter J. Gardner, David A. Copland, Sidath E. Liyanage, Anai Gonzalez-Cordero, Sophia-Martha kleine Holthaus, Ulrich F. O. Luhmann, Alexander J. Smith, Robin R. Ali, Andrew D. Dick

Disease Models & Mechanisms Apr 2016, 9 (4) 473-481; DOI: 10.1242/dmm.022475
New Wistar Kyoto and spontaneously hypertensive rat transgenic models with ubiquitous expression of green fluorescent protein
Ana Isabel Garcia Diaz, Ben Moyon, Philip M. Coan, Neza Alfazema, Lara Venda, Kevin Woollard, Tim Aitman

Disease Models & Mechanisms Apr 2016, 9 (4) 463-471; DOI: 10.1242/dmm.024208
Standardized orthotopic xenografts in zebrafish reveal glioma cell-line-specific characteristics and tumor cell heterogeneity
Alessandra M. Welker, Brian D. Jaros, Vinay K. Puduvalli, Jaime Imitola, Balveen Kaur, Christine E. Beattie

Disease Models & Mechanisms Feb 2016, 9 (2) 199-210; DOI: 10.1242/dmm.022921
Generation of brain tumours in mice by Cre-mediated recombination of neural progenitors in situ with the tamoxifen metabolite endoxifen
Anna Benedykcinska, Andreia Ferreira, Joanne Lau, Jessica Broni, Angela Richard-Loendt, Nico V. Henriquez, Sebastian Brandner

Disease Models & Mechanisms Feb 2016, 9 (2) 211-220; DOI: 10.1242/dmm.022715
Pulmonary transcriptome analysis in the surgically induced rabbit model of diaphragmatic hernia treated with fetal tracheal occlusion
Alexander C. Engels, Paul D. Brady, Molka Kammoun, Julio Finalet Ferreiro, Philip DeKoninck, Masayuki Endo, Jaan Toelen, Joris R. Vermeesch, Jan Deprest

Disease Models & Mechanisms Feb 2016, 9 (2) 221-228; DOI: 10.1242/dmm.021626
Urine-sample-derived human induced pluripotent stem cells as a model to study PCSK9-mediated autosomal dominant hypercholesterolemia
Karim Si-Tayeb, Salam Idriss, Benoite Champon, Amandine Caillaud, Matthieu Pichelin, Lucie Arnaud, Patricia Lemarchand, Cédric Le May, Kazem Zibara, Bertrand Cariou

Disease Models & Mechanisms Jan 2016, 9 (1) 81-90; DOI: 10.1242/dmm.022277
Longitudinal micro-CT provides biomarkers of lung disease that can be used to assess the effect of therapy in preclinical mouse models, and reveal compensatory changes in lung volume
Greetje Vande Velde, Jennifer Poelmans, Ellen De Langhe, Amy Hillen, Jeroen Vanoirbeek, Uwe Himmelreich, Rik J. Lories

Disease Models & Mechanisms Jan 2016, 9 (1) 91-98; DOI: 10.1242/dmm.020321
A modified choline-deficient, ethionine-supplemented diet reduces morbidity and retains a liver progenitor cell response in mice
Adam M. Passman, Robyn P. Strauss, Sarah B. McSpadden, Megan L. Finch-Edmondson, Ken H. Woo, Luke A. Diepeveen, Roslyn London, Bernard A. Callus, George C. Yeoh

Disease Models & Mechanisms Dec 2015, 8 (12) 1635-1641; DOI: 10.1242/dmm.022020

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Disease Models & Mechanisms

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