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RESEARCH ARTICLE
Conditional deletion of AP-2β in mouse cranial neural crest results in anterior segment dysgenesis and early-onset glaucoma
Vanessa B. Martino, Thomas Sabljic, Paula Deschamps, Rebecca M. Green, Monica Akula, Erica Peacock, Alexander Ball, Trevor Williams, Judith A. West-Mays
Disease Models & Mechanisms 2016 9: 849-861; doi: 10.1242/dmm.025262
Vanessa B. Martino
1Department of Pathology and Molecular Medicine, McMaster University Health Science Centre, Room 4N65, 1200 Main St. West, Hamilton, Ontario, Canada L8N 3Z5
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Thomas Sabljic
1Department of Pathology and Molecular Medicine, McMaster University Health Science Centre, Room 4N65, 1200 Main St. West, Hamilton, Ontario, Canada L8N 3Z5
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Paula Deschamps
1Department of Pathology and Molecular Medicine, McMaster University Health Science Centre, Room 4N65, 1200 Main St. West, Hamilton, Ontario, Canada L8N 3Z5
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Rebecca M. Green
2Department of Craniofacial Biology, University of Colorado Denver, Anschutz Medical Campus, Mailstop 8120, RC-1 South Building, 11th Floor, Room 111, 12801 East 17th Ave. P.O., Aurora, CO 80045, USA
3Department of Cell and Developmental Biology, University of Colorado Denver, Anschutz Medical Campus, Mailstop 8120, RC-1 South Building, 11th Floor, Room 111, 12801 East 17th Ave. P.O., Aurora, CO 80045, USA
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Monica Akula
1Department of Pathology and Molecular Medicine, McMaster University Health Science Centre, Room 4N65, 1200 Main St. West, Hamilton, Ontario, Canada L8N 3Z5
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Erica Peacock
1Department of Pathology and Molecular Medicine, McMaster University Health Science Centre, Room 4N65, 1200 Main St. West, Hamilton, Ontario, Canada L8N 3Z5
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Alexander Ball
1Department of Pathology and Molecular Medicine, McMaster University Health Science Centre, Room 4N65, 1200 Main St. West, Hamilton, Ontario, Canada L8N 3Z5
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Trevor Williams
2Department of Craniofacial Biology, University of Colorado Denver, Anschutz Medical Campus, Mailstop 8120, RC-1 South Building, 11th Floor, Room 111, 12801 East 17th Ave. P.O., Aurora, CO 80045, USA
3Department of Cell and Developmental Biology, University of Colorado Denver, Anschutz Medical Campus, Mailstop 8120, RC-1 South Building, 11th Floor, Room 111, 12801 East 17th Ave. P.O., Aurora, CO 80045, USA
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  • ORCID record for Trevor Williams
  • For correspondence: Trevor.Williams@ucdenver.edu westmayj@mcmaster.ca
Judith A. West-Mays
1Department of Pathology and Molecular Medicine, McMaster University Health Science Centre, Room 4N65, 1200 Main St. West, Hamilton, Ontario, Canada L8N 3Z5
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  • For correspondence: Trevor.Williams@ucdenver.edu westmayj@mcmaster.ca
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Article Information

vol. 9 no. 8, 849-861

DOI 
https://doi.org/10.1242/dmm.025262
PubMed 
27483349

Published By 
The Company of Biologists Ltd
Print ISSN 
1754-8403
Online ISSN 
1754-8411
History 
  • Received March 4, 2016
  • Accepted June 21, 2016
  • Published online August 3, 2016.
Posted online 
June 23, 2016
Copyright & Usage 
© 2016. Published by The Company of Biologists Ltd This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/3.0), which permits unrestricted use, distribution and reproduction in any medium provided that the original work is properly attributed.

Article Versions

  • Previous version (June 23, 2016 - 05:33).
  • You are viewing the most recent version of this article.

Author Information

  1. Vanessa B. Martino1,
  2. Thomas Sabljic1,
  3. Paula Deschamps1,
  4. Rebecca M. Green2,3,
  5. Monica Akula1,
  6. Erica Peacock1,
  7. Alexander Ball1,
  8. Trevor Williams2,3,* and
  9. Judith A. West-Mays1,*
  1. 1Department of Pathology and Molecular Medicine, McMaster University Health Science Centre, Room 4N65, 1200 Main St. West, Hamilton, Ontario, Canada L8N 3Z5
  2. 2Department of Craniofacial Biology, University of Colorado Denver, Anschutz Medical Campus, Mailstop 8120, RC-1 South Building, 11th Floor, Room 111, 12801 East 17th Ave. P.O., Aurora, CO 80045, USA
  3. 3Department of Cell and Developmental Biology, University of Colorado Denver, Anschutz Medical Campus, Mailstop 8120, RC-1 South Building, 11th Floor, Room 111, 12801 East 17th Ave. P.O., Aurora, CO 80045, USA
  1. ↵*Authors for correspondence (Trevor.Williams{at}ucdenver.edu; westmayj{at}mcmaster.ca)

Article usage

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Aug 202001110
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Oct 202036321
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Total 202027265214
Jan 202112013
Total 202112013
Total94920501919

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Keywords

  • Anterior segment dysgenesis
  • Glaucoma
  • AP-2β

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RESEARCH ARTICLE
Conditional deletion of AP-2β in mouse cranial neural crest results in anterior segment dysgenesis and early-onset glaucoma
Vanessa B. Martino, Thomas Sabljic, Paula Deschamps, Rebecca M. Green, Monica Akula, Erica Peacock, Alexander Ball, Trevor Williams, Judith A. West-Mays
Disease Models & Mechanisms 2016 9: 849-861; doi: 10.1242/dmm.025262
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RESEARCH ARTICLE
Conditional deletion of AP-2β in mouse cranial neural crest results in anterior segment dysgenesis and early-onset glaucoma
Vanessa B. Martino, Thomas Sabljic, Paula Deschamps, Rebecca M. Green, Monica Akula, Erica Peacock, Alexander Ball, Trevor Williams, Judith A. West-Mays
Disease Models & Mechanisms 2016 9: 849-861; doi: 10.1242/dmm.025262

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