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Review
Fishing for causes and cures of motor neuron disorders
Shunmoogum A. Patten, Gary A. B. Armstrong, Alexandra Lissouba, Edor Kabashi, J. Alex Parker, Pierre Drapeau
Disease Models & Mechanisms 2014 7: 799-809; doi: 10.1242/dmm.015719
Shunmoogum A. Patten
Department of Neuroscience, FRQS Groupe de Recherche sur le Système Nerveux Central and CRCHUM, University of Montréal, Montréal, QC H3A 2B4, Canada.
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Gary A. B. Armstrong
Department of Neuroscience, FRQS Groupe de Recherche sur le Système Nerveux Central and CRCHUM, University of Montréal, Montréal, QC H3A 2B4, Canada.
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Alexandra Lissouba
Department of Neuroscience, FRQS Groupe de Recherche sur le Système Nerveux Central and CRCHUM, University of Montréal, Montréal, QC H3A 2B4, Canada.
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Edor Kabashi
Institut du Cerveau et de la Moelle Épinière, Centre de Recherche, CHU Pitié-Salpétrière, 75013 Paris, France.
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J. Alex Parker
Department of Neuroscience, FRQS Groupe de Recherche sur le Système Nerveux Central and CRCHUM, University of Montréal, Montréal, QC H3A 2B4, Canada.
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Pierre Drapeau
Department of Neuroscience, FRQS Groupe de Recherche sur le Système Nerveux Central and CRCHUM, University of Montréal, Montréal, QC H3A 2B4, Canada.
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  • For correspondence: p.drapeau@umontreal.ca
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Article Information

vol. 7 no. 7, 799-809

DOI 
https://doi.org/10.1242/dmm.015719
PubMed 
24973750

Published By 
The Company of Biologists Ltd
Print ISSN 
1754-8403
Online ISSN 
1754-8411
History 
  • Published online June 27, 2014.
Copyright & Usage 
© 2014. Published by The Company of Biologists Ltd This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/3.0), which permits unrestricted use, distribution and reproduction in any medium provided that the original work is properly attributed.


Author Information

  1. Shunmoogum A. Patten1,
  2. Gary A. B. Armstrong1,
  3. Alexandra Lissouba1,
  4. Edor Kabashi2,
  5. J. Alex Parker1 and
  6. Pierre Drapeau1,*
  1. 1Department of Neuroscience, FRQS Groupe de Recherche sur le Système Nerveux Central and CRCHUM, University of Montréal, Montréal, QC H3A 2B4, Canada.
  2. 2Institut du Cerveau et de la Moelle Épinière, Centre de Recherche, CHU Pitié-Salpétrière, 75013 Paris, France.
  1. ↵* Author for correspondence (p.drapeau{at}umontreal.ca)
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Keywords

  • ALS
  • HSP
  • SMA
  • Zebrafish
  • Drug discovery
  • Motor neuron disorders

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Review
Fishing for causes and cures of motor neuron disorders
Shunmoogum A. Patten, Gary A. B. Armstrong, Alexandra Lissouba, Edor Kabashi, J. Alex Parker, Pierre Drapeau
Disease Models & Mechanisms 2014 7: 799-809; doi: 10.1242/dmm.015719
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Review
Fishing for causes and cures of motor neuron disorders
Shunmoogum A. Patten, Gary A. B. Armstrong, Alexandra Lissouba, Edor Kabashi, J. Alex Parker, Pierre Drapeau
Disease Models & Mechanisms 2014 7: 799-809; doi: 10.1242/dmm.015719

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Article navigation

  • Top
  • Article
    • Abstract
    • Introduction
    • Common pathological pathways between the different MNDs
    • The zebrafish toolbox: how useful is it for studying MNDs?
    • Zebrafish as a tool for drug screening
    • Spinal muscular atrophy (SMA)
    • Amyotrophic lateral sclerosis (ALS)
    • Hereditary spastic paraplegia (HSP)
    • Chemical screens in zebrafish models for other neural diseases
    • Concluding remarks and perspectives
    • Footnotes
    • References
  • Figures & tables
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