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Cover: Courtesy of Christopher M. Dooley, Wellcome Trust Sanger Institute.
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First person — Andrew Scott Emmert and Eri Iwasawa
In an interview, first authors Andrew Scott Emmert and Eri Iwasawa discuss their new paper on impaired CSF flow and neural differentiation in a rat model of hydrocephalus, their research process and plans for the future.
Ethan Perlstein and colleagues present two back-to-back articles. In the first, they describe how the diabetic neuropathy drug palrestat can ameliorate PMM2-CDG. The second identifies the FDA-approved aripiprazole as a clinical candidate for treating NGLY1 deficiency.
Read Murgia et al.’s new resource article describing a SILAC-based proteomics approach to quantify the unfolded protein response.
We're excited to be an affiliate journal for Review Commons, the ASAPbio/EMBO platform for high-quality journal-independent peer-review in the life sciences, which went live on 09 December.