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  Open access

June, 2014; 7 (6)

IN THIS ISSUE

  • Open Access
    A microRNA mechanism that regulates regeneration after spinal cord injury in amphibians
    Disease Models & Mechanisms 2014 7: e601
  • Open Access
    Analysis of GEMMs helps unravel genetic heterogeneity in colorectal cancer
    Disease Models & Mechanisms 2014 7: e602
  • Open Access
    Evidence that modifier loci have no effect on phenotypic severity in SHANK3-linked autism
    Disease Models & Mechanisms 2014 7: e603
  • Open Access
    New mechanistic insight: neural cell death in diabetes-linked depression
    Disease Models & Mechanisms 2014 7: e604

REVIEW

  • Open Access
    Understanding positional cues in salamander limb regeneration: implications for optimizing cell-based regenerative therapies
    Catherine D. McCusker, David M. Gardiner
    Disease Models & Mechanisms 2014 7: 593-599; doi: 10.1242/dmm.013359

RESEARCH ARTICLES

  • Open Access
    Precise control of miR-125b levels is required to create a regeneration-permissive environment after spinal cord injury: a cross-species comparison between salamander and rat
    Juan Felipe Diaz Quiroz, Eve Tsai, Matthew Coyle, Tina Sehm, Karen Echeverri
    Disease Models & Mechanisms 2014 7: 601-611; doi: 10.1242/dmm.014837
  • Open Access
    Cross-species analysis of genetically engineered mouse models of MAPK-driven colorectal cancer identifies hallmarks of the human disease
    Peter J. Belmont, Eva Budinska, Ping Jiang, Mark J. Sinnamon, Erin Coffee, Jatin Roper, Tao Xie, Paul A. Rejto, Sahra Derkits, Owen J. Sansom, Mauro Delorenzi, Sabine Tejpar, Kenneth E. Hung, Eric S. Martin
    Disease Models & Mechanisms 2014 7: 613-623; doi: 10.1242/dmm.013904
  • Open Access
    Role of insulin signaling impairment, adiponectin and dyslipidemia in peripheral and central neuropathy in mice
    Nicholas J. Anderson, Matthew R. King, Lina Delbruck, Corinne G. Jolivalt
    Disease Models & Mechanisms 2014 7: 625-633; doi: 10.1242/dmm.015750
  • Open Access
    Phenotypic rescue of a Drosophila model of mitochondrial ANT1 disease
    Suvi Vartiainen, Shanjun Chen, Jack George, Tea Tuomela, Kaisa R. Luoto, Kevin M. C. O’Dell, Howard T. Jacobs
    Disease Models & Mechanisms 2014 7: 635-648; doi: 10.1242/dmm.016527
  • Open Access
    A new mouse model of Canavan leukodystrophy displays hearing impairment due to central nervous system dysmyelination
    Marina R. Carpinelli, Anne K. Voss, Michael G. Manning, Ashwyn A. Perera, Anne A. Cooray, Benjamin T. Kile, Rachel A. Burt
    Disease Models & Mechanisms 2014 7: 649-657; doi: 10.1242/dmm.014605
  • Open Access
    The chaperone domain BRICHOS prevents CNS toxicity of amyloid-β peptide in Drosophila melanogaster
    Erik Hermansson, Sebastian Schultz, Damian Crowther, Sara Linse, Bengt Winblad, Gunilla Westermark, Jan Johansson, Jenny Presto
    Disease Models & Mechanisms 2014 7: 659-665; doi: 10.1242/dmm.014787
  • Open Access
    Absence of strong strain effects in behavioral analyses of Shank3-deficient mice
    Elodie Drapeau, Nate P. Dorr, Gregory A. Elder, Joseph D. Buxbaum
    Disease Models & Mechanisms 2014 7: 667-681; doi: 10.1242/dmm.013821
  • Open Access
    Kelch-like ECT2-interacting protein KLEIP regulates late-stage pulmonary maturation via Hif-2α in mice
    Nicole Woik, Christian T. Dietz, Kathrin Schäker, Jens Kroll
    Disease Models & Mechanisms 2014 7: 683-692; doi: 10.1242/dmm.014266
  • Open Access
    Cryptosporidium parvum-induced ileo-caecal adenocarcinoma and Wnt signaling in a mouse model
    Sadia Benamrouz, Valerie Conseil, Magali Chabé, Marleen Praet, Christophe Audebert, Renaud Blervaque, Karine Guyot, Sophie Gazzola, Anthony Mouray, Thierry Chassat, Baptiste Delaire, Nathalie Goetinck, Nausicaa Gantois, Marwan Osman, Christian Slomianny, Vanessa Dehennaut, Tony Lefebvre, Eric Viscogliosi, Claude Cuvelier, Eduardo Dei-Cas, Colette Creusy, Gabriela Certad
    Disease Models & Mechanisms 2014 7: 693-700; doi: 10.1242/dmm.013292
  • Open Access
    Balance between the two kinin receptors in the progression of experimental focal and segmental glomerulosclerosis in mice
    Rafael Luiz Pereira, Raphael José Ferreira Felizardo, Marcos Antônio Cenedeze, Meire Ioshie Hiyane, Ênio José Bassi, Mariane Tami Amano, Clarice Sylvia Taemi Origassa, Reinaldo Correia Silva, Cristhiane Fávero Aguiar, Sylvia Mendes Carneiro, João Bosco Pesquero, Ronaldo Carvalho Araújo, Alexandre de Castro Keller, Renato C. Monteiro, Ivan Cruz Moura, Alvaro Pacheco-Silva, Niels Olsen Saraiva Câmara
    Disease Models & Mechanisms 2014 7: 701-710; doi: 10.1242/dmm.014548
  • Open Access
    A novel mouse model of Warburg Micro syndrome reveals roles for RAB18 in eye development and organisation of the neuronal cytoskeleton
    Sarah M. Carpanini, Lisa McKie, Derek Thomson, Ann K. Wright, Sarah L. Gordon, Sarah L. Roche, Mark T. Handley, Harris Morrison, David Brownstein, Thomas M. Wishart, Michael A. Cousin, Thomas H. Gillingwater, Irene A. Aligianis, Ian J. Jackson
    Disease Models & Mechanisms 2014 7: 711-722; doi: 10.1242/dmm.015222
  • Open Access
    Contribution of neural cell death to depressive phenotypes of streptozotocin-induced diabetic mice
    Cheng Chen, Yun Wang, Juan Zhang, Lian Ma, Jiang Gu, Guyu Ho
    Disease Models & Mechanisms 2014 7: 723-730; doi: 10.1242/dmm.016162
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  • Open Access

    Neural crest-specific deletion of Bmp7 leads to midfacial hypoplasia, nasal airway obstruction, and disordered breathing modelling Obstructive Sleep Apnea

    Pranidhi Baddam, Vivian Biancardi, Daniela M. Roth, Farah Eaton, Claudine Thereza-Bussolaro, Rupasri Mandal, David S. Wishart, Amy Barr, Joanna MacLean, Carlos Flores-Mir, Silvia Pagliardini, Daniel Graf
    PDF
  • Open Access

    Inducible expression of human C9ORF72 36x G4C2 hexanucleotide repeats is sufficient to cause RAN translation and rapid muscular atrophy in mice

    F. W. Riemslagh, E. C. van der Toorn, R. F. M. Verhagen, A. Maas, L. W. J. Bosman, R. K. Hukema, R. Willemsen
    PDF
  • Open Access

    A muscle growth promoting treatment based on the attenuation of activin/myostatin signalling in young mice results in long-term testicular abnormalities

    Danielle Vaughan, Robert Mitchell, Oliver Kretz, David Chambers, Maciej Lalowski, Helge Amthor, Olli Ritvos, Arja Pasternack, Antonios Matsakas, Sakthivel Vaiyapuri, Tobias B. Huber, Bernd Denecke, Abir Mukherjee, Darius Widera, Ketan Patel
    PDF
  • Open Access

    TDP-43 mislocalization drives neurofilament changes in a novel model of TDP-43 proteinopathy

    Rachel Atkinson, Jacqueline Leung, James Bender, Matthew Kirkcaldie, James Vickers, Anna King
    PDF
  • Open Access

    Interpreting the pathogenicity of Joubert Syndrome missense variants in Caenorhabditis elegans

    Karen I. Lange, Sofia Tsiropoulou, Katarzyna Kucharska, Oliver E. Blacque
    PDF
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