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Resource Articles
Screen for abnormal mitochondrial phenotypes in mouse embryonic stem cells identifies a model for succinyl-CoA ligase deficiency and mtDNA depletion
Taraka R. Donti, Carmen Stromberger, Ming Ge, Karen W. Eldin, William J. Craigen, Brett H. Graham
Disease Models & Mechanisms 2014 7: 271-280; doi: 10.1242/dmm.013466
Taraka R. Donti
1Department of Molecular and Human Genetics, Baylor College of Medicine, One Baylor Plaza, Houston, TX 77030, USA.
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Carmen Stromberger
1Department of Molecular and Human Genetics, Baylor College of Medicine, One Baylor Plaza, Houston, TX 77030, USA.
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Ming Ge
1Department of Molecular and Human Genetics, Baylor College of Medicine, One Baylor Plaza, Houston, TX 77030, USA.
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Karen W. Eldin
2Department of Pathology and Immunology, Baylor College of Medicine, One Baylor Plaza, Houston, TX 77030, USA.
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William J. Craigen
1Department of Molecular and Human Genetics, Baylor College of Medicine, One Baylor Plaza, Houston, TX 77030, USA.
3Department of Pediatrics, Baylor College of Medicine, One Baylor Plaza, Houston, TX 77030, USA.
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Brett H. Graham
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  • For correspondence: bgraham@bcm.edu
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Article Information

vol. 7 no. 2, 271-280

DOI 
https://doi.org/10.1242/dmm.013466
PubMed 
24271779

Published By 
The Company of Biologists Ltd
Print ISSN 
1754-8403
Online ISSN 
1754-8411
History 
  • Received June 27, 2013
  • Accepted November 18, 2013
  • Published online February 7, 2014.
Posted online 
November 21, 2013
Copyright & Usage 
© 2014. Published by The Company of Biologists Ltd This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/3.0), which permits unrestricted use, distribution and reproduction in any medium provided that the original work is properly attributed.

Article Versions

  • Previous version (November 21, 2013 - 08:03).
  • You are viewing the most recent version of this article.

Author Information

  1. Taraka R. Donti1,‡,
  2. Carmen Stromberger1,*,‡,
  3. Ming Ge1,
  4. Karen W. Eldin2,
  5. William J. Craigen1,3 and
  6. Brett H. Graham§
  1. 1Department of Molecular and Human Genetics, Baylor College of Medicine, One Baylor Plaza, Houston, TX 77030, USA.
  2. 2Department of Pathology and Immunology, Baylor College of Medicine, One Baylor Plaza, Houston, TX 77030, USA.
  3. 3Department of Pediatrics, Baylor College of Medicine, One Baylor Plaza, Houston, TX 77030, USA.
  1. ↵§ Author for correspondence (bgraham{at}bcm.edu)
  1. ↵‡ These authors contributed equally to this work

  • ↵* Present address: Department of Radiooncology, Charité University Hospital, Campus CCM and CVK, Augustenburger Platz 1, 13353 Berlin, Germany.

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Keywords

  • TCA cycle
  • Mitochondrial DNA depletion
  • Gene trap
  • Mitochondria

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Resource Articles
Screen for abnormal mitochondrial phenotypes in mouse embryonic stem cells identifies a model for succinyl-CoA ligase deficiency and mtDNA depletion
Taraka R. Donti, Carmen Stromberger, Ming Ge, Karen W. Eldin, William J. Craigen, Brett H. Graham
Disease Models & Mechanisms 2014 7: 271-280; doi: 10.1242/dmm.013466
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Resource Articles
Screen for abnormal mitochondrial phenotypes in mouse embryonic stem cells identifies a model for succinyl-CoA ligase deficiency and mtDNA depletion
Taraka R. Donti, Carmen Stromberger, Ming Ge, Karen W. Eldin, William J. Craigen, Brett H. Graham
Disease Models & Mechanisms 2014 7: 271-280; doi: 10.1242/dmm.013466

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