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May, 2013; 6 (3)

A

  1. Adams, David

    1. Special Article
      Bloomsbury report on mouse embryo phenotyping: recommendations from the IMPC workshop on embryonic lethal screening
      David Adams, Richard Baldock, Shoumo Bhattacharya, Andrew J. Copp, Mary Dickinson, Nicholas D. E. Greene, Mark Henkelman, Monica Justice, Timothy Mohun, Stephen A. Murray, Erwin Pauws, Michael Raess, Janet Rossant, Tom Weaver, David West
      Disease Models & Mechanisms 2013 6: 571-579; doi: 10.1242/dmm.011833

  2. Adams, David J.

    1. Editorial
      Deciphering the Mechanisms of Developmental Disorders (DMDD): a new programme for phenotyping embryonic lethal mice
      Timothy Mohun, David J. Adams, Richard Baldock, Shoumo Bhattacharya, Andrew J. Copp, Myriam Hemberger, Corinne Houart, Matt E. Hurles, Elizabeth Robertson, James C. Smith, Tom Weaver, Wolfgang Weninger
      Disease Models & Mechanisms 2013 6: 562-566; doi: 10.1242/dmm.011957

  3. Adarichev, Vyacheslav A.

    1. Research Article
      Osteoarticular tissue infection and development of skeletal pathology in murine brucellosis
      Diogo M. Magnani, Elizabeth T. Lyons, Toni S. Forde, Mohammed T. Shekhani, Vyacheslav A. Adarichev, Gary A. Splitter
      Disease Models & Mechanisms 2013 6: 811-818; doi: 10.1242/dmm.011056

  4. Ahmed, Jehangir N.

    1. Research Article
      A murine Zic3 transcript with a premature termination codon evades nonsense-mediated decay during axis formation
      Jehangir N. Ahmed, Radiya G. Ali, Nicholas Warr, Heather M. Wilson, Helen M. Bellchambers, Kristen S. Barratt, Amelia J. Thompson, Ruth M. Arkell
      Disease Models & Mechanisms 2013 6: 755-767; doi: 10.1242/dmm.011668

  5. Ali, Radiya G.

    1. Research Article
      A murine Zic3 transcript with a premature termination codon evades nonsense-mediated decay during axis formation
      Jehangir N. Ahmed, Radiya G. Ali, Nicholas Warr, Heather M. Wilson, Helen M. Bellchambers, Kristen S. Barratt, Amelia J. Thompson, Ruth M. Arkell
      Disease Models & Mechanisms 2013 6: 755-767; doi: 10.1242/dmm.011668

  6. Allan, Kirsten

    1. Research Article
      In Drosophila, RhoGEF2 cooperates with activated Ras in tumorigenesis through a pathway involving Rho1–Rok–Myosin-II and JNK signalling
      Peytee Khoo, Kirsten Allan, Lee Willoughby, Anthony M. Brumby, Helena E. Richardson
      Disease Models & Mechanisms 2013 6: 661-678; doi: 10.1242/dmm.010066

  7. André, Cécile

    1. Research Article
      Neurons and cardiomyocytes derived from induced pluripotent stem cells as a model for mitochondrial defects in Friedreich’s ataxia
      Aurore Hick, Marie Wattenhofer-Donzé, Satyan Chintawar, Philippe Tropel, Jodie P. Simard, Nadège Vaucamps, David Gall, Laurie Lambot, Cécile André, Laurence Reutenauer, Myriam Rai, Marius Teletin, Nadia Messaddeq, Serge N. Schiffmann, Stéphane Viville, Christopher E. Pearson, Massimo Pandolfo, Hélène Puccio
      Disease Models & Mechanisms 2013 6: 608-621; doi: 10.1242/dmm.010900

  8. Antin, Parker B.

    1. Research Article
      Olfactomedin-1 activity identifies a cell invasion checkpoint during epithelial-mesenchymal transition in the chick embryonic heart
      Alejandro Lencinas, Danny C. Chhun, Kelvin P. Dan, Kristen D. Ross, Elizabeth A. Hoover, Parker B. Antin, Raymond B. Runyan
      Disease Models & Mechanisms 2013 6: 632-642; doi: 10.1242/dmm.010595

  9. Arkell, Ruth M.

    1. Research Article
      A murine Zic3 transcript with a premature termination codon evades nonsense-mediated decay during axis formation
      Jehangir N. Ahmed, Radiya G. Ali, Nicholas Warr, Heather M. Wilson, Helen M. Bellchambers, Kristen S. Barratt, Amelia J. Thompson, Ruth M. Arkell
      Disease Models & Mechanisms 2013 6: 755-767; doi: 10.1242/dmm.011668

  10. Armstrong-James, Darius

    1. Research Article
      A new and clinically relevant murine model of solid-organ transplant aspergillosis
      Susanne Herbst, Anand Shah, Martin Carby, Gary Chusney, Naresh Kikkeri, Anthony Dorling, Elaine Bignell, Sunil Shaunak, Darius Armstrong-James
      Disease Models & Mechanisms 2013 6: 643-651; doi: 10.1242/dmm.010330

B

  1. Baldock, Richard

    1. Editorial
      Deciphering the Mechanisms of Developmental Disorders (DMDD): a new programme for phenotyping embryonic lethal mice
      Timothy Mohun, David J. Adams, Richard Baldock, Shoumo Bhattacharya, Andrew J. Copp, Myriam Hemberger, Corinne Houart, Matt E. Hurles, Elizabeth Robertson, James C. Smith, Tom Weaver, Wolfgang Weninger
      Disease Models & Mechanisms 2013 6: 562-566; doi: 10.1242/dmm.011957
    2. Special Article
      Bloomsbury report on mouse embryo phenotyping: recommendations from the IMPC workshop on embryonic lethal screening
      David Adams, Richard Baldock, Shoumo Bhattacharya, Andrew J. Copp, Mary Dickinson, Nicholas D. E. Greene, Mark Henkelman, Monica Justice, Timothy Mohun, Stephen A. Murray, Erwin Pauws, Michael Raess, Janet Rossant, Tom Weaver, David West
      Disease Models & Mechanisms 2013 6: 571-579; doi: 10.1242/dmm.011833

  2. Barakat-Walter, Ibtissam

    1. Research Article
      Functional and histopathological identification of the respiratory failure in a DMSXL transgenic mouse model of myotonic dystrophy
      Petrica-Adrian Panaite, Thierry Kuntzer, Geneviève Gourdon, Johannes Alexander Lobrinus, Ibtissam Barakat-Walter
      Disease Models & Mechanisms 2013 6: 622-631; doi: 10.1242/dmm.010512

  3. Barratt, Kristen S.

    1. Research Article
      A murine Zic3 transcript with a premature termination codon evades nonsense-mediated decay during axis formation
      Jehangir N. Ahmed, Radiya G. Ali, Nicholas Warr, Heather M. Wilson, Helen M. Bellchambers, Kristen S. Barratt, Amelia J. Thompson, Ruth M. Arkell
      Disease Models & Mechanisms 2013 6: 755-767; doi: 10.1242/dmm.011668

  4. Bassuk, Alexander G.

    1. Research Article
      Mechanisms of prickle1a function in zebrafish epilepsy and retinal neurogenesis
      Xue Mei, Shu Wu, Alexander G. Bassuk, Diane C. Slusarski
      Disease Models & Mechanisms 2013 6: 679-688; doi: 10.1242/dmm.010793

  5. Beales, Philip L.

    1. Research Article
      Generation and validation of a zebrafish model of EAST (epilepsy, ataxia, sensorineural deafness and tubulopathy) syndrome
      Fahad Mahmood, Monika Mozere, Anselm A. Zdebik, Horia C. Stanescu, Jonathan Tobin, Philip L. Beales, Robert Kleta, Detlef Bockenhauer, Claire Russell
      Disease Models & Mechanisms 2013 6: 652-660; doi: 10.1242/dmm.009480

  6. Bedard, Karen

    1. Research Article
      Loss of the E3 ubiquitin ligase LRSAM1 sensitizes peripheral axons to degeneration in a mouse model of Charcot-Marie-Tooth disease
      Laurent P. Bogdanik, James N. Sleigh, Cong Tian, Mark E. Samuels, Karen Bedard, Kevin L. Seburn, Robert W. Burgess
      Disease Models & Mechanisms 2013 6: 780-792; doi: 10.1242/dmm.010942

  7. Bellchambers, Helen M.

    1. Research Article
      A murine Zic3 transcript with a premature termination codon evades nonsense-mediated decay during axis formation
      Jehangir N. Ahmed, Radiya G. Ali, Nicholas Warr, Heather M. Wilson, Helen M. Bellchambers, Kristen S. Barratt, Amelia J. Thompson, Ruth M. Arkell
      Disease Models & Mechanisms 2013 6: 755-767; doi: 10.1242/dmm.011668

  8. Berardinelli, Maria Grazia

    1. Research Article
      A necrotic stimulus is required to maximize matrix-mediated myogenesis in mice
      Drew Kuraitis, Maria Grazia Berardinelli, Erik J. Suuronen, Antonio Musarò
      Disease Models & Mechanisms 2013 6: 793-801; doi: 10.1242/dmm.011072

  9. Bergadà, Laura

    1. Research Article
      An inducible knockout mouse to model the cell-autonomous role of PTEN in initiating endometrial, prostate and thyroid neoplasias
      Cristina Mirantes, Núria Eritja, Maria Alba Dosil, Maria Santacana, Judit Pallares, Sónia Gatius, Laura Bergadà, Oscar Maiques, Xavier Matias-Guiu, Xavier Dolcet
      Disease Models & Mechanisms 2013 6: 710-720; doi: 10.1242/dmm.011445

  10. Beyer, Joseph

    1. Resource Article
      An entirely automated method to score DSS-induced colitis in mice by digital image analysis of pathology slides
      Cleopatra Kozlowski, Surinder Jeet, Joseph Beyer, Steve Guerrero, Justin Lesch, Xiaoting Wang, Jason DeVoss, Lauri Diehl
      Disease Models & Mechanisms 2013 6: 855-865; doi: 10.1242/dmm.011759

  11. Bhattacharya, Shoumo

    1. Editorial
      Deciphering the Mechanisms of Developmental Disorders (DMDD): a new programme for phenotyping embryonic lethal mice
      Timothy Mohun, David J. Adams, Richard Baldock, Shoumo Bhattacharya, Andrew J. Copp, Myriam Hemberger, Corinne Houart, Matt E. Hurles, Elizabeth Robertson, James C. Smith, Tom Weaver, Wolfgang Weninger
      Disease Models & Mechanisms 2013 6: 562-566; doi: 10.1242/dmm.011957
    2. Special Article
      Bloomsbury report on mouse embryo phenotyping: recommendations from the IMPC workshop on embryonic lethal screening
      David Adams, Richard Baldock, Shoumo Bhattacharya, Andrew J. Copp, Mary Dickinson, Nicholas D. E. Greene, Mark Henkelman, Monica Justice, Timothy Mohun, Stephen A. Murray, Erwin Pauws, Michael Raess, Janet Rossant, Tom Weaver, David West
      Disease Models & Mechanisms 2013 6: 571-579; doi: 10.1242/dmm.011833

  12. Bignell, Elaine

    1. Research Article
      A new and clinically relevant murine model of solid-organ transplant aspergillosis
      Susanne Herbst, Anand Shah, Martin Carby, Gary Chusney, Naresh Kikkeri, Anthony Dorling, Elaine Bignell, Sunil Shaunak, Darius Armstrong-James
      Disease Models & Mechanisms 2013 6: 643-651; doi: 10.1242/dmm.010330

  13. Bitsche, Mario

    1. Research Article
      Sepsis otopathy: experimental sepsis leads to significant hearing impairment due to apoptosis and glutamate excitotoxicity in murine cochlea
      Joachim Schmutzhard, Rudolf Glueckert, Christian Pritz, Michael J. F. Blumer, Mario Bitsche, Peter Lackner, Manfred Fille, Herbert Riechelmann, Matthias Harkamp, Thongrong Sitthisak, Annelies Schrott-Fischer
      Disease Models & Mechanisms 2013 6: 745-754; doi: 10.1242/dmm.011205

  14. Blanco, Gonzalo

    1. Research Report
      The fraction of strongly bound cross-bridges is increased in mice that carry the myopathy-linked myosin heavy chain mutation MYH4L342Q
      Johan Lindqvist, Hiroyuki Iwamoto, Gonzalo Blanco, Julien Ochala
      Disease Models & Mechanisms 2013 6: 834-840; doi: 10.1242/dmm.011155

  15. Blumer, Michael J. F.

    1. Research Article
      Sepsis otopathy: experimental sepsis leads to significant hearing impairment due to apoptosis and glutamate excitotoxicity in murine cochlea
      Joachim Schmutzhard, Rudolf Glueckert, Christian Pritz, Michael J. F. Blumer, Mario Bitsche, Peter Lackner, Manfred Fille, Herbert Riechelmann, Matthias Harkamp, Thongrong Sitthisak, Annelies Schrott-Fischer
      Disease Models & Mechanisms 2013 6: 745-754; doi: 10.1242/dmm.011205

  16. Bockenhauer, Detlef

    1. Research Article
      Generation and validation of a zebrafish model of EAST (epilepsy, ataxia, sensorineural deafness and tubulopathy) syndrome
      Fahad Mahmood, Monika Mozere, Anselm A. Zdebik, Horia C. Stanescu, Jonathan Tobin, Philip L. Beales, Robert Kleta, Detlef Bockenhauer, Claire Russell
      Disease Models & Mechanisms 2013 6: 652-660; doi: 10.1242/dmm.009480

  17. Boehringer, Ashley V.

    1. Research Article
      Motor neurons and glia exhibit specific individualized responses to TDP-43 expression in a Drosophila model of amyotrophic lateral sclerosis
      Patricia S. Estes, Scott G. Daniel, Abigail P. Mccallum, Ashley V. Boehringer, Alona S. Sukhina, Rebecca A. Zwick, Daniela C. Zarnescu
      Disease Models & Mechanisms 2013 6: 721-733; doi: 10.1242/dmm.010710

  18. Bogdanik, Laurent P.

    1. Research Article
      Loss of the E3 ubiquitin ligase LRSAM1 sensitizes peripheral axons to degeneration in a mouse model of Charcot-Marie-Tooth disease
      Laurent P. Bogdanik, James N. Sleigh, Cong Tian, Mark E. Samuels, Karen Bedard, Kevin L. Seburn, Robert W. Burgess
      Disease Models & Mechanisms 2013 6: 780-792; doi: 10.1242/dmm.010942

  19. Brumby, Anthony M.

    1. Research Article
      In Drosophila, RhoGEF2 cooperates with activated Ras in tumorigenesis through a pathway involving Rho1–Rok–Myosin-II and JNK signalling
      Peytee Khoo, Kirsten Allan, Lee Willoughby, Anthony M. Brumby, Helena E. Richardson
      Disease Models & Mechanisms 2013 6: 661-678; doi: 10.1242/dmm.010066

  20. Burgess, Robert W.

    1. Research Article
      Loss of the E3 ubiquitin ligase LRSAM1 sensitizes peripheral axons to degeneration in a mouse model of Charcot-Marie-Tooth disease
      Laurent P. Bogdanik, James N. Sleigh, Cong Tian, Mark E. Samuels, Karen Bedard, Kevin L. Seburn, Robert W. Burgess
      Disease Models & Mechanisms 2013 6: 780-792; doi: 10.1242/dmm.010942

C

  1. Cagan, Ross L.

    1. Editorial
      Bridging the gap between basic and applied biology: towards preclinical translation
      Ross L. Cagan, Monica J. Justice, George F. Tidmarsh
      Disease Models & Mechanisms 2013 6: 559-561; doi: 10.1242/dmm.012450

  2. Carby, Martin

    1. Research Article
      A new and clinically relevant murine model of solid-organ transplant aspergillosis
      Susanne Herbst, Anand Shah, Martin Carby, Gary Chusney, Naresh Kikkeri, Anthony Dorling, Elaine Bignell, Sunil Shaunak, Darius Armstrong-James
      Disease Models & Mechanisms 2013 6: 643-651; doi: 10.1242/dmm.010330

  3. Chernet, Brook T.

    1. Research Article
      Transmembrane voltage potential is an essential cellular parameter for the detection and control of tumor development in a Xenopus model
      Brook T. Chernet, Michael Levin
      Disease Models & Mechanisms 2013 6: 595-607; doi: 10.1242/dmm.010835

  4. Chhun, Danny C.

    1. Research Article
      Olfactomedin-1 activity identifies a cell invasion checkpoint during epithelial-mesenchymal transition in the chick embryonic heart
      Alejandro Lencinas, Danny C. Chhun, Kelvin P. Dan, Kristen D. Ross, Elizabeth A. Hoover, Parker B. Antin, Raymond B. Runyan
      Disease Models & Mechanisms 2013 6: 632-642; doi: 10.1242/dmm.010595

  5. Chintawar, Satyan

    1. Research Article
      Neurons and cardiomyocytes derived from induced pluripotent stem cells as a model for mitochondrial defects in Friedreich’s ataxia
      Aurore Hick, Marie Wattenhofer-Donzé, Satyan Chintawar, Philippe Tropel, Jodie P. Simard, Nadège Vaucamps, David Gall, Laurie Lambot, Cécile André, Laurence Reutenauer, Myriam Rai, Marius Teletin, Nadia Messaddeq, Serge N. Schiffmann, Stéphane Viville, Christopher E. Pearson, Massimo Pandolfo, Hélène Puccio
      Disease Models & Mechanisms 2013 6: 608-621; doi: 10.1242/dmm.010900

  6. Chusney, Gary

    1. Research Article
      A new and clinically relevant murine model of solid-organ transplant aspergillosis
      Susanne Herbst, Anand Shah, Martin Carby, Gary Chusney, Naresh Kikkeri, Anthony Dorling, Elaine Bignell, Sunil Shaunak, Darius Armstrong-James
      Disease Models & Mechanisms 2013 6: 643-651; doi: 10.1242/dmm.010330

  7. Collino, Massimo

    1. Research Article
      Pharmacological preconditioning with erythropoietin attenuates the organ injury and dysfunction induced in a rat model of hemorrhagic shock
      Kiran K. Nandra, Massimo Collino, Mara Rogazzo, Roberto Fantozzi, Nimesh S. A. Patel, Christoph Thiemermann
      Disease Models & Mechanisms 2013 6: 701-709; doi: 10.1242/dmm.011353

  8. Copp, Andrew J.

    1. Editorial
      Deciphering the Mechanisms of Developmental Disorders (DMDD): a new programme for phenotyping embryonic lethal mice
      Timothy Mohun, David J. Adams, Richard Baldock, Shoumo Bhattacharya, Andrew J. Copp, Myriam Hemberger, Corinne Houart, Matt E. Hurles, Elizabeth Robertson, James C. Smith, Tom Weaver, Wolfgang Weninger
      Disease Models & Mechanisms 2013 6: 562-566; doi: 10.1242/dmm.011957
    2. Special Article
      Bloomsbury report on mouse embryo phenotyping: recommendations from the IMPC workshop on embryonic lethal screening
      David Adams, Richard Baldock, Shoumo Bhattacharya, Andrew J. Copp, Mary Dickinson, Nicholas D. E. Greene, Mark Henkelman, Monica Justice, Timothy Mohun, Stephen A. Murray, Erwin Pauws, Michael Raess, Janet Rossant, Tom Weaver, David West
      Disease Models & Mechanisms 2013 6: 571-579; doi: 10.1242/dmm.011833

D

  1. Dan, Kelvin P.

    1. Research Article
      Olfactomedin-1 activity identifies a cell invasion checkpoint during epithelial-mesenchymal transition in the chick embryonic heart
      Alejandro Lencinas, Danny C. Chhun, Kelvin P. Dan, Kristen D. Ross, Elizabeth A. Hoover, Parker B. Antin, Raymond B. Runyan
      Disease Models & Mechanisms 2013 6: 632-642; doi: 10.1242/dmm.010595

  2. Daniel, Scott G.

    1. Research Article
      Motor neurons and glia exhibit specific individualized responses to TDP-43 expression in a Drosophila model of amyotrophic lateral sclerosis
      Patricia S. Estes, Scott G. Daniel, Abigail P. Mccallum, Ashley V. Boehringer, Alona S. Sukhina, Rebecca A. Zwick, Daniela C. Zarnescu
      Disease Models & Mechanisms 2013 6: 721-733; doi: 10.1242/dmm.010710

  3. DeVoss, Jason

    1. Resource Article
      An entirely automated method to score DSS-induced colitis in mice by digital image analysis of pathology slides
      Cleopatra Kozlowski, Surinder Jeet, Joseph Beyer, Steve Guerrero, Justin Lesch, Xiaoting Wang, Jason DeVoss, Lauri Diehl
      Disease Models & Mechanisms 2013 6: 855-865; doi: 10.1242/dmm.011759

  4. Dickinson, Mary

    1. Special Article
      Bloomsbury report on mouse embryo phenotyping: recommendations from the IMPC workshop on embryonic lethal screening
      David Adams, Richard Baldock, Shoumo Bhattacharya, Andrew J. Copp, Mary Dickinson, Nicholas D. E. Greene, Mark Henkelman, Monica Justice, Timothy Mohun, Stephen A. Murray, Erwin Pauws, Michael Raess, Janet Rossant, Tom Weaver, David West
      Disease Models & Mechanisms 2013 6: 571-579; doi: 10.1242/dmm.011833

  5. Diehl, Lauri

    1. Resource Article
      An entirely automated method to score DSS-induced colitis in mice by digital image analysis of pathology slides
      Cleopatra Kozlowski, Surinder Jeet, Joseph Beyer, Steve Guerrero, Justin Lesch, Xiaoting Wang, Jason DeVoss, Lauri Diehl
      Disease Models & Mechanisms 2013 6: 855-865; doi: 10.1242/dmm.011759

  6. Dolcet, Xavier

    1. Research Article
      An inducible knockout mouse to model the cell-autonomous role of PTEN in initiating endometrial, prostate and thyroid neoplasias
      Cristina Mirantes, Núria Eritja, Maria Alba Dosil, Maria Santacana, Judit Pallares, Sónia Gatius, Laura Bergadà, Oscar Maiques, Xavier Matias-Guiu, Xavier Dolcet
      Disease Models & Mechanisms 2013 6: 710-720; doi: 10.1242/dmm.011445

  7. Dorling, Anthony

    1. Research Article
      A new and clinically relevant murine model of solid-organ transplant aspergillosis
      Susanne Herbst, Anand Shah, Martin Carby, Gary Chusney, Naresh Kikkeri, Anthony Dorling, Elaine Bignell, Sunil Shaunak, Darius Armstrong-James
      Disease Models & Mechanisms 2013 6: 643-651; doi: 10.1242/dmm.010330

  8. Dosil, Maria Alba

    1. Research Article
      An inducible knockout mouse to model the cell-autonomous role of PTEN in initiating endometrial, prostate and thyroid neoplasias
      Cristina Mirantes, Núria Eritja, Maria Alba Dosil, Maria Santacana, Judit Pallares, Sónia Gatius, Laura Bergadà, Oscar Maiques, Xavier Matias-Guiu, Xavier Dolcet
      Disease Models & Mechanisms 2013 6: 710-720; doi: 10.1242/dmm.011445

E

  1. Egeblad, Mikala

    1. Review
      Caught in the act: revealing the metastatic process by live imaging
      Miriam R. Fein, Mikala Egeblad
      Disease Models & Mechanisms 2013 6: 580-593; doi: 10.1242/dmm.009282

  2. Eritja, Núria

    1. Research Article
      An inducible knockout mouse to model the cell-autonomous role of PTEN in initiating endometrial, prostate and thyroid neoplasias
      Cristina Mirantes, Núria Eritja, Maria Alba Dosil, Maria Santacana, Judit Pallares, Sónia Gatius, Laura Bergadà, Oscar Maiques, Xavier Matias-Guiu, Xavier Dolcet
      Disease Models & Mechanisms 2013 6: 710-720; doi: 10.1242/dmm.011445

  3. Estes, Patricia S.

    1. Research Article
      Motor neurons and glia exhibit specific individualized responses to TDP-43 expression in a Drosophila model of amyotrophic lateral sclerosis
      Patricia S. Estes, Scott G. Daniel, Abigail P. Mccallum, Ashley V. Boehringer, Alona S. Sukhina, Rebecca A. Zwick, Daniela C. Zarnescu
      Disease Models & Mechanisms 2013 6: 721-733; doi: 10.1242/dmm.010710

F

  1. Fantozzi, Roberto

    1. Research Article
      Pharmacological preconditioning with erythropoietin attenuates the organ injury and dysfunction induced in a rat model of hemorrhagic shock
      Kiran K. Nandra, Massimo Collino, Mara Rogazzo, Roberto Fantozzi, Nimesh S. A. Patel, Christoph Thiemermann
      Disease Models & Mechanisms 2013 6: 701-709; doi: 10.1242/dmm.011353

  2. Fein, Miriam R.

    1. Review
      Caught in the act: revealing the metastatic process by live imaging
      Miriam R. Fein, Mikala Egeblad
      Disease Models & Mechanisms 2013 6: 580-593; doi: 10.1242/dmm.009282

  3. Fille, Manfred

    1. Research Article
      Sepsis otopathy: experimental sepsis leads to significant hearing impairment due to apoptosis and glutamate excitotoxicity in murine cochlea
      Joachim Schmutzhard, Rudolf Glueckert, Christian Pritz, Michael J. F. Blumer, Mario Bitsche, Peter Lackner, Manfred Fille, Herbert Riechelmann, Matthias Harkamp, Thongrong Sitthisak, Annelies Schrott-Fischer
      Disease Models & Mechanisms 2013 6: 745-754; doi: 10.1242/dmm.011205

  4. Forde, Toni S.

    1. Research Article
      Osteoarticular tissue infection and development of skeletal pathology in murine brucellosis
      Diogo M. Magnani, Elizabeth T. Lyons, Toni S. Forde, Mohammed T. Shekhani, Vyacheslav A. Adarichev, Gary A. Splitter
      Disease Models & Mechanisms 2013 6: 811-818; doi: 10.1242/dmm.011056

  5. Fumagalli, Arianna

    1. Research Article
      Elevated expression of the V-ATPase C subunit triggers JNK-dependent cell invasion and overgrowth in a Drosophila epithelium
      Astrid G. Petzoldt, Eva Maria Gleixner, Arianna Fumagalli, Thomas Vaccari, Matias Simons
      Disease Models & Mechanisms 2013 6: 689-700; doi: 10.1242/dmm.010660

G

  1. Gall, David

    1. Research Article
      Neurons and cardiomyocytes derived from induced pluripotent stem cells as a model for mitochondrial defects in Friedreich’s ataxia
      Aurore Hick, Marie Wattenhofer-Donzé, Satyan Chintawar, Philippe Tropel, Jodie P. Simard, Nadège Vaucamps, David Gall, Laurie Lambot, Cécile André, Laurence Reutenauer, Myriam Rai, Marius Teletin, Nadia Messaddeq, Serge N. Schiffmann, Stéphane Viville, Christopher E. Pearson, Massimo Pandolfo, Hélène Puccio
      Disease Models & Mechanisms 2013 6: 608-621; doi: 10.1242/dmm.010900

  2. Gatius, Sónia

    1. Research Article
      An inducible knockout mouse to model the cell-autonomous role of PTEN in initiating endometrial, prostate and thyroid neoplasias
      Cristina Mirantes, Núria Eritja, Maria Alba Dosil, Maria Santacana, Judit Pallares, Sónia Gatius, Laura Bergadà, Oscar Maiques, Xavier Matias-Guiu, Xavier Dolcet
      Disease Models & Mechanisms 2013 6: 710-720; doi: 10.1242/dmm.011445

  3. Gleixner, Eva Maria

    1. Research Article
      Elevated expression of the V-ATPase C subunit triggers JNK-dependent cell invasion and overgrowth in a Drosophila epithelium
      Astrid G. Petzoldt, Eva Maria Gleixner, Arianna Fumagalli, Thomas Vaccari, Matias Simons
      Disease Models & Mechanisms 2013 6: 689-700; doi: 10.1242/dmm.010660

  4. Glueckert, Rudolf

    1. Research Article
      Sepsis otopathy: experimental sepsis leads to significant hearing impairment due to apoptosis and glutamate excitotoxicity in murine cochlea
      Joachim Schmutzhard, Rudolf Glueckert, Christian Pritz, Michael J. F. Blumer, Mario Bitsche, Peter Lackner, Manfred Fille, Herbert Riechelmann, Matthias Harkamp, Thongrong Sitthisak, Annelies Schrott-Fischer
      Disease Models & Mechanisms 2013 6: 745-754; doi: 10.1242/dmm.011205

  5. Gourdon, Geneviève

    1. Research Article
      Functional and histopathological identification of the respiratory failure in a DMSXL transgenic mouse model of myotonic dystrophy
      Petrica-Adrian Panaite, Thierry Kuntzer, Geneviève Gourdon, Johannes Alexander Lobrinus, Ibtissam Barakat-Walter
      Disease Models & Mechanisms 2013 6: 622-631; doi: 10.1242/dmm.010512

  6. Greene, Nicholas D. E.

    1. Special Article
      Bloomsbury report on mouse embryo phenotyping: recommendations from the IMPC workshop on embryonic lethal screening
      David Adams, Richard Baldock, Shoumo Bhattacharya, Andrew J. Copp, Mary Dickinson, Nicholas D. E. Greene, Mark Henkelman, Monica Justice, Timothy Mohun, Stephen A. Murray, Erwin Pauws, Michael Raess, Janet Rossant, Tom Weaver, David West
      Disease Models & Mechanisms 2013 6: 571-579; doi: 10.1242/dmm.011833

  7. Guerrero, Steve

    1. Resource Article
      An entirely automated method to score DSS-induced colitis in mice by digital image analysis of pathology slides
      Cleopatra Kozlowski, Surinder Jeet, Joseph Beyer, Steve Guerrero, Justin Lesch, Xiaoting Wang, Jason DeVoss, Lauri Diehl
      Disease Models & Mechanisms 2013 6: 855-865; doi: 10.1242/dmm.011759

  8. Guillemin, Karen

    1. Research Article
      H. pylori virulence factor CagA increases intestinal cell proliferation by Wnt pathway activation in a transgenic zebrafish model
      James T. Neal, Tracy S. Peterson, Michael L. Kent, Karen Guillemin
      Disease Models & Mechanisms 2013 6: 802-810; doi: 10.1242/dmm.011163

H

  1. Han, Min

    1. Research Report
      piggyBac as a high-capacity transgenesis and gene-therapy vector in human cells and mice
      Rongbo Li, Yuan Zhuang, Min Han, Tian Xu, Xiaohui Wu
      Disease Models & Mechanisms 2013 6: 828-833; doi: 10.1242/dmm.010827

  2. Harkamp, Matthias

    1. Research Article
      Sepsis otopathy: experimental sepsis leads to significant hearing impairment due to apoptosis and glutamate excitotoxicity in murine cochlea
      Joachim Schmutzhard, Rudolf Glueckert, Christian Pritz, Michael J. F. Blumer, Mario Bitsche, Peter Lackner, Manfred Fille, Herbert Riechelmann, Matthias Harkamp, Thongrong Sitthisak, Annelies Schrott-Fischer
      Disease Models & Mechanisms 2013 6: 745-754; doi: 10.1242/dmm.011205

  3. Hasan, Gaiti

    1. Research Article
      Altered lipid homeostasis in Drosophila InsP3 receptor mutants leads to obesity and hyperphagia
      Manivannan Subramanian, Suman Kumar Metya, Sufia Sadaf, Satish Kumar, Dominik Schwudke, Gaiti Hasan
      Disease Models & Mechanisms 2013 6: 734-744; doi: 10.1242/dmm.010017

  4. Havrda, Matthew C.

    1. Research Report
      Behavioral abnormalities and Parkinson’s-like histological changes resulting from Id2 inactivation in mice
      Matthew C. Havrda, Brenton R. Paolella, Nora M. Ward, Kathryn B. Holroyd
      Disease Models & Mechanisms 2013 6: 819-827; doi: 10.1242/dmm.010041

  5. Hemberger, Myriam

    1. Editorial
      Deciphering the Mechanisms of Developmental Disorders (DMDD): a new programme for phenotyping embryonic lethal mice
      Timothy Mohun, David J. Adams, Richard Baldock, Shoumo Bhattacharya, Andrew J. Copp, Myriam Hemberger, Corinne Houart, Matt E. Hurles, Elizabeth Robertson, James C. Smith, Tom Weaver, Wolfgang Weninger
      Disease Models & Mechanisms 2013 6: 562-566; doi: 10.1242/dmm.011957

  6. Henkelman, Mark

    1. Special Article
      Bloomsbury report on mouse embryo phenotyping: recommendations from the IMPC workshop on embryonic lethal screening
      David Adams, Richard Baldock, Shoumo Bhattacharya, Andrew J. Copp, Mary Dickinson, Nicholas D. E. Greene, Mark Henkelman, Monica Justice, Timothy Mohun, Stephen A. Murray, Erwin Pauws, Michael Raess, Janet Rossant, Tom Weaver, David West
      Disease Models & Mechanisms 2013 6: 571-579; doi: 10.1242/dmm.011833

  7. Herbst, Susanne

    1. Research Article
      A new and clinically relevant murine model of solid-organ transplant aspergillosis
      Susanne Herbst, Anand Shah, Martin Carby, Gary Chusney, Naresh Kikkeri, Anthony Dorling, Elaine Bignell, Sunil Shaunak, Darius Armstrong-James
      Disease Models & Mechanisms 2013 6: 643-651; doi: 10.1242/dmm.010330

  8. Hick, Aurore

    1. Research Article
      Neurons and cardiomyocytes derived from induced pluripotent stem cells as a model for mitochondrial defects in Friedreich’s ataxia
      Aurore Hick, Marie Wattenhofer-Donzé, Satyan Chintawar, Philippe Tropel, Jodie P. Simard, Nadège Vaucamps, David Gall, Laurie Lambot, Cécile André, Laurence Reutenauer, Myriam Rai, Marius Teletin, Nadia Messaddeq, Serge N. Schiffmann, Stéphane Viville, Christopher E. Pearson, Massimo Pandolfo, Hélène Puccio
      Disease Models & Mechanisms 2013 6: 608-621; doi: 10.1242/dmm.010900

  9. Holmes, Greg

    1. Research Article
      From shape to cells: mouse models reveal mechanisms altering palate development in Apert syndrome
      Neus Martínez-Abadías, Greg Holmes, Talia Pankratz, Yingli Wang, Xueyan Zhou, Ethylin Wang Jabs, Joan T. Richtsmeier
      Disease Models & Mechanisms 2013 6: 768-779; doi: 10.1242/dmm.010397

  10. Holroyd, Kathryn B.

    1. Research Report
      Behavioral abnormalities and Parkinson’s-like histological changes resulting from Id2 inactivation in mice
      Matthew C. Havrda, Brenton R. Paolella, Nora M. Ward, Kathryn B. Holroyd
      Disease Models & Mechanisms 2013 6: 819-827; doi: 10.1242/dmm.010041

  11. Hoover, Elizabeth A.

    1. Research Article
      Olfactomedin-1 activity identifies a cell invasion checkpoint during epithelial-mesenchymal transition in the chick embryonic heart
      Alejandro Lencinas, Danny C. Chhun, Kelvin P. Dan, Kristen D. Ross, Elizabeth A. Hoover, Parker B. Antin, Raymond B. Runyan
      Disease Models & Mechanisms 2013 6: 632-642; doi: 10.1242/dmm.010595

  12. Houart, Corinne

    1. Editorial
      Deciphering the Mechanisms of Developmental Disorders (DMDD): a new programme for phenotyping embryonic lethal mice
      Timothy Mohun, David J. Adams, Richard Baldock, Shoumo Bhattacharya, Andrew J. Copp, Myriam Hemberger, Corinne Houart, Matt E. Hurles, Elizabeth Robertson, James C. Smith, Tom Weaver, Wolfgang Weninger
      Disease Models & Mechanisms 2013 6: 562-566; doi: 10.1242/dmm.011957

  13. Hurles, Matt E.

    1. Editorial
      Deciphering the Mechanisms of Developmental Disorders (DMDD): a new programme for phenotyping embryonic lethal mice
      Timothy Mohun, David J. Adams, Richard Baldock, Shoumo Bhattacharya, Andrew J. Copp, Myriam Hemberger, Corinne Houart, Matt E. Hurles, Elizabeth Robertson, James C. Smith, Tom Weaver, Wolfgang Weninger
      Disease Models & Mechanisms 2013 6: 562-566; doi: 10.1242/dmm.011957

I

  1. Iwamoto, Hiroyuki

    1. Research Report
      The fraction of strongly bound cross-bridges is increased in mice that carry the myopathy-linked myosin heavy chain mutation MYH4L342Q
      Johan Lindqvist, Hiroyuki Iwamoto, Gonzalo Blanco, Julien Ochala
      Disease Models & Mechanisms 2013 6: 834-840; doi: 10.1242/dmm.011155

J

  1. Jabs, Ethylin Wang

    1. Research Article
      From shape to cells: mouse models reveal mechanisms altering palate development in Apert syndrome
      Neus Martínez-Abadías, Greg Holmes, Talia Pankratz, Yingli Wang, Xueyan Zhou, Ethylin Wang Jabs, Joan T. Richtsmeier
      Disease Models & Mechanisms 2013 6: 768-779; doi: 10.1242/dmm.010397

  2. Jeet, Surinder

    1. Resource Article
      An entirely automated method to score DSS-induced colitis in mice by digital image analysis of pathology slides
      Cleopatra Kozlowski, Surinder Jeet, Joseph Beyer, Steve Guerrero, Justin Lesch, Xiaoting Wang, Jason DeVoss, Lauri Diehl
      Disease Models & Mechanisms 2013 6: 855-865; doi: 10.1242/dmm.011759

  3. Justice, Monica

    1. Special Article
      Bloomsbury report on mouse embryo phenotyping: recommendations from the IMPC workshop on embryonic lethal screening
      David Adams, Richard Baldock, Shoumo Bhattacharya, Andrew J. Copp, Mary Dickinson, Nicholas D. E. Greene, Mark Henkelman, Monica Justice, Timothy Mohun, Stephen A. Murray, Erwin Pauws, Michael Raess, Janet Rossant, Tom Weaver, David West
      Disease Models & Mechanisms 2013 6: 571-579; doi: 10.1242/dmm.011833

  4. Justice, Monica J.

    1. Editorial
      Bridging the gap between basic and applied biology: towards preclinical translation
      Ross L. Cagan, Monica J. Justice, George F. Tidmarsh
      Disease Models & Mechanisms 2013 6: 559-561; doi: 10.1242/dmm.012450

K

  1. Kent, Michael L.

    1. Research Article
      H. pylori virulence factor CagA increases intestinal cell proliferation by Wnt pathway activation in a transgenic zebrafish model
      James T. Neal, Tracy S. Peterson, Michael L. Kent, Karen Guillemin
      Disease Models & Mechanisms 2013 6: 802-810; doi: 10.1242/dmm.011163

  2. Khoo, Peytee

    1. Research Article
      In Drosophila, RhoGEF2 cooperates with activated Ras in tumorigenesis through a pathway involving Rho1–Rok–Myosin-II and JNK signalling
      Peytee Khoo, Kirsten Allan, Lee Willoughby, Anthony M. Brumby, Helena E. Richardson
      Disease Models & Mechanisms 2013 6: 661-678; doi: 10.1242/dmm.010066

  3. Kikkeri, Naresh

    1. Research Article
      A new and clinically relevant murine model of solid-organ transplant aspergillosis
      Susanne Herbst, Anand Shah, Martin Carby, Gary Chusney, Naresh Kikkeri, Anthony Dorling, Elaine Bignell, Sunil Shaunak, Darius Armstrong-James
      Disease Models & Mechanisms 2013 6: 643-651; doi: 10.1242/dmm.010330

  4. Kleta, Robert

    1. Research Article
      Generation and validation of a zebrafish model of EAST (epilepsy, ataxia, sensorineural deafness and tubulopathy) syndrome
      Fahad Mahmood, Monika Mozere, Anselm A. Zdebik, Horia C. Stanescu, Jonathan Tobin, Philip L. Beales, Robert Kleta, Detlef Bockenhauer, Claire Russell
      Disease Models & Mechanisms 2013 6: 652-660; doi: 10.1242/dmm.009480

  5. Kozlowski, Cleopatra

    1. Resource Article
      An entirely automated method to score DSS-induced colitis in mice by digital image analysis of pathology slides
      Cleopatra Kozlowski, Surinder Jeet, Joseph Beyer, Steve Guerrero, Justin Lesch, Xiaoting Wang, Jason DeVoss, Lauri Diehl
      Disease Models & Mechanisms 2013 6: 855-865; doi: 10.1242/dmm.011759

  6. Kumar, Satish

    1. Research Article
      Altered lipid homeostasis in Drosophila InsP3 receptor mutants leads to obesity and hyperphagia
      Manivannan Subramanian, Suman Kumar Metya, Sufia Sadaf, Satish Kumar, Dominik Schwudke, Gaiti Hasan
      Disease Models & Mechanisms 2013 6: 734-744; doi: 10.1242/dmm.010017

  7. Kuntzer, Thierry

    1. Research Article
      Functional and histopathological identification of the respiratory failure in a DMSXL transgenic mouse model of myotonic dystrophy
      Petrica-Adrian Panaite, Thierry Kuntzer, Geneviève Gourdon, Johannes Alexander Lobrinus, Ibtissam Barakat-Walter
      Disease Models & Mechanisms 2013 6: 622-631; doi: 10.1242/dmm.010512

  8. Kuraitis, Drew

    1. Research Article
      A necrotic stimulus is required to maximize matrix-mediated myogenesis in mice
      Drew Kuraitis, Maria Grazia Berardinelli, Erik J. Suuronen, Antonio Musarò
      Disease Models & Mechanisms 2013 6: 793-801; doi: 10.1242/dmm.011072

L

  1. Lackner, Peter

    1. Research Article
      Sepsis otopathy: experimental sepsis leads to significant hearing impairment due to apoptosis and glutamate excitotoxicity in murine cochlea
      Joachim Schmutzhard, Rudolf Glueckert, Christian Pritz, Michael J. F. Blumer, Mario Bitsche, Peter Lackner, Manfred Fille, Herbert Riechelmann, Matthias Harkamp, Thongrong Sitthisak, Annelies Schrott-Fischer
      Disease Models & Mechanisms 2013 6: 745-754; doi: 10.1242/dmm.011205

  2. Lambot, Laurie

    1. Research Article
      Neurons and cardiomyocytes derived from induced pluripotent stem cells as a model for mitochondrial defects in Friedreich’s ataxia
      Aurore Hick, Marie Wattenhofer-Donzé, Satyan Chintawar, Philippe Tropel, Jodie P. Simard, Nadège Vaucamps, David Gall, Laurie Lambot, Cécile André, Laurence Reutenauer, Myriam Rai, Marius Teletin, Nadia Messaddeq, Serge N. Schiffmann, Stéphane Viville, Christopher E. Pearson, Massimo Pandolfo, Hélène Puccio
      Disease Models & Mechanisms 2013 6: 608-621; doi: 10.1242/dmm.010900

  3. Lencinas, Alejandro

    1. Research Article
      Olfactomedin-1 activity identifies a cell invasion checkpoint during epithelial-mesenchymal transition in the chick embryonic heart
      Alejandro Lencinas, Danny C. Chhun, Kelvin P. Dan, Kristen D. Ross, Elizabeth A. Hoover, Parker B. Antin, Raymond B. Runyan
      Disease Models & Mechanisms 2013 6: 632-642; doi: 10.1242/dmm.010595

  4. Lesch, Justin

    1. Resource Article
      An entirely automated method to score DSS-induced colitis in mice by digital image analysis of pathology slides
      Cleopatra Kozlowski, Surinder Jeet, Joseph Beyer, Steve Guerrero, Justin Lesch, Xiaoting Wang, Jason DeVoss, Lauri Diehl
      Disease Models & Mechanisms 2013 6: 855-865; doi: 10.1242/dmm.011759

  5. Levin, Michael

    1. Research Article
      Transmembrane voltage potential is an essential cellular parameter for the detection and control of tumor development in a Xenopus model
      Brook T. Chernet, Michael Levin
      Disease Models & Mechanisms 2013 6: 595-607; doi: 10.1242/dmm.010835

  6. Li, Rongbo

    1. Research Report
      piggyBac as a high-capacity transgenesis and gene-therapy vector in human cells and mice
      Rongbo Li, Yuan Zhuang, Min Han, Tian Xu, Xiaohui Wu
      Disease Models & Mechanisms 2013 6: 828-833; doi: 10.1242/dmm.010827

  7. Lindqvist, Johan

    1. Research Report
      The fraction of strongly bound cross-bridges is increased in mice that carry the myopathy-linked myosin heavy chain mutation MYH4L342Q
      Johan Lindqvist, Hiroyuki Iwamoto, Gonzalo Blanco, Julien Ochala
      Disease Models & Mechanisms 2013 6: 834-840; doi: 10.1242/dmm.011155

  8. Lobrinus, Johannes Alexander

    1. Research Article
      Functional and histopathological identification of the respiratory failure in a DMSXL transgenic mouse model of myotonic dystrophy
      Petrica-Adrian Panaite, Thierry Kuntzer, Geneviève Gourdon, Johannes Alexander Lobrinus, Ibtissam Barakat-Walter
      Disease Models & Mechanisms 2013 6: 622-631; doi: 10.1242/dmm.010512

  9. Lyons, Elizabeth T.

    1. Research Article
      Osteoarticular tissue infection and development of skeletal pathology in murine brucellosis
      Diogo M. Magnani, Elizabeth T. Lyons, Toni S. Forde, Mohammed T. Shekhani, Vyacheslav A. Adarichev, Gary A. Splitter
      Disease Models & Mechanisms 2013 6: 811-818; doi: 10.1242/dmm.011056

M

  1. Magnani, Diogo M.

    1. Research Article
      Osteoarticular tissue infection and development of skeletal pathology in murine brucellosis
      Diogo M. Magnani, Elizabeth T. Lyons, Toni S. Forde, Mohammed T. Shekhani, Vyacheslav A. Adarichev, Gary A. Splitter
      Disease Models & Mechanisms 2013 6: 811-818; doi: 10.1242/dmm.011056

  2. Mahmood, Fahad

    1. Research Article
      Generation and validation of a zebrafish model of EAST (epilepsy, ataxia, sensorineural deafness and tubulopathy) syndrome
      Fahad Mahmood, Monika Mozere, Anselm A. Zdebik, Horia C. Stanescu, Jonathan Tobin, Philip L. Beales, Robert Kleta, Detlef Bockenhauer, Claire Russell
      Disease Models & Mechanisms 2013 6: 652-660; doi: 10.1242/dmm.009480

  3. Maiques, Oscar

    1. Research Article
      An inducible knockout mouse to model the cell-autonomous role of PTEN in initiating endometrial, prostate and thyroid neoplasias
      Cristina Mirantes, Núria Eritja, Maria Alba Dosil, Maria Santacana, Judit Pallares, Sónia Gatius, Laura Bergadà, Oscar Maiques, Xavier Matias-Guiu, Xavier Dolcet
      Disease Models & Mechanisms 2013 6: 710-720; doi: 10.1242/dmm.011445

  4. Martínez-Abadías, Neus

    1. Research Article
      From shape to cells: mouse models reveal mechanisms altering palate development in Apert syndrome
      Neus Martínez-Abadías, Greg Holmes, Talia Pankratz, Yingli Wang, Xueyan Zhou, Ethylin Wang Jabs, Joan T. Richtsmeier
      Disease Models & Mechanisms 2013 6: 768-779; doi: 10.1242/dmm.010397

  5. Matias-Guiu, Xavier

    1. Research Article
      An inducible knockout mouse to model the cell-autonomous role of PTEN in initiating endometrial, prostate and thyroid neoplasias
      Cristina Mirantes, Núria Eritja, Maria Alba Dosil, Maria Santacana, Judit Pallares, Sónia Gatius, Laura Bergadà, Oscar Maiques, Xavier Matias-Guiu, Xavier Dolcet
      Disease Models & Mechanisms 2013 6: 710-720; doi: 10.1242/dmm.011445

  6. Mccallum, Abigail P.

    1. Research Article
      Motor neurons and glia exhibit specific individualized responses to TDP-43 expression in a Drosophila model of amyotrophic lateral sclerosis
      Patricia S. Estes, Scott G. Daniel, Abigail P. Mccallum, Ashley V. Boehringer, Alona S. Sukhina, Rebecca A. Zwick, Daniela C. Zarnescu
      Disease Models & Mechanisms 2013 6: 721-733; doi: 10.1242/dmm.010710

  7. Mei, Xue

    1. Research Article
      Mechanisms of prickle1a function in zebrafish epilepsy and retinal neurogenesis
      Xue Mei, Shu Wu, Alexander G. Bassuk, Diane C. Slusarski
      Disease Models & Mechanisms 2013 6: 679-688; doi: 10.1242/dmm.010793

  8. Meijer, Annemarie H.

    1. Resource Article
      Functional analysis of a zebrafish myd88 mutant identifies key transcriptional components of the innate immune system
      Michiel van der Vaart, Joost J. van Soest, Herman P. Spaink, Annemarie H. Meijer
      Disease Models & Mechanisms 2013 6: 841-854; doi: 10.1242/dmm.010843

  9. Messaddeq, Nadia

    1. Research Article
      Neurons and cardiomyocytes derived from induced pluripotent stem cells as a model for mitochondrial defects in Friedreich’s ataxia
      Aurore Hick, Marie Wattenhofer-Donzé, Satyan Chintawar, Philippe Tropel, Jodie P. Simard, Nadège Vaucamps, David Gall, Laurie Lambot, Cécile André, Laurence Reutenauer, Myriam Rai, Marius Teletin, Nadia Messaddeq, Serge N. Schiffmann, Stéphane Viville, Christopher E. Pearson, Massimo Pandolfo, Hélène Puccio
      Disease Models & Mechanisms 2013 6: 608-621; doi: 10.1242/dmm.010900

  10. Metya, Suman Kumar

    1. Research Article
      Altered lipid homeostasis in Drosophila InsP3 receptor mutants leads to obesity and hyperphagia
      Manivannan Subramanian, Suman Kumar Metya, Sufia Sadaf, Satish Kumar, Dominik Schwudke, Gaiti Hasan
      Disease Models & Mechanisms 2013 6: 734-744; doi: 10.1242/dmm.010017

  11. Mirantes, Cristina

    1. Research Article
      An inducible knockout mouse to model the cell-autonomous role of PTEN in initiating endometrial, prostate and thyroid neoplasias
      Cristina Mirantes, Núria Eritja, Maria Alba Dosil, Maria Santacana, Judit Pallares, Sónia Gatius, Laura Bergadà, Oscar Maiques, Xavier Matias-Guiu, Xavier Dolcet
      Disease Models & Mechanisms 2013 6: 710-720; doi: 10.1242/dmm.011445

  12. Mohun, Timothy

    1. Editorial
      Deciphering the Mechanisms of Developmental Disorders (DMDD): a new programme for phenotyping embryonic lethal mice
      Timothy Mohun, David J. Adams, Richard Baldock, Shoumo Bhattacharya, Andrew J. Copp, Myriam Hemberger, Corinne Houart, Matt E. Hurles, Elizabeth Robertson, James C. Smith, Tom Weaver, Wolfgang Weninger
      Disease Models & Mechanisms 2013 6: 562-566; doi: 10.1242/dmm.011957
    2. Special Article
      Bloomsbury report on mouse embryo phenotyping: recommendations from the IMPC workshop on embryonic lethal screening
      David Adams, Richard Baldock, Shoumo Bhattacharya, Andrew J. Copp, Mary Dickinson, Nicholas D. E. Greene, Mark Henkelman, Monica Justice, Timothy Mohun, Stephen A. Murray, Erwin Pauws, Michael Raess, Janet Rossant, Tom Weaver, David West
      Disease Models & Mechanisms 2013 6: 571-579; doi: 10.1242/dmm.011833

  13. Mozere, Monika

    1. Research Article
      Generation and validation of a zebrafish model of EAST (epilepsy, ataxia, sensorineural deafness and tubulopathy) syndrome
      Fahad Mahmood, Monika Mozere, Anselm A. Zdebik, Horia C. Stanescu, Jonathan Tobin, Philip L. Beales, Robert Kleta, Detlef Bockenhauer, Claire Russell
      Disease Models & Mechanisms 2013 6: 652-660; doi: 10.1242/dmm.009480

  14. Murray, Stephen A.

    1. Special Article
      Bloomsbury report on mouse embryo phenotyping: recommendations from the IMPC workshop on embryonic lethal screening
      David Adams, Richard Baldock, Shoumo Bhattacharya, Andrew J. Copp, Mary Dickinson, Nicholas D. E. Greene, Mark Henkelman, Monica Justice, Timothy Mohun, Stephen A. Murray, Erwin Pauws, Michael Raess, Janet Rossant, Tom Weaver, David West
      Disease Models & Mechanisms 2013 6: 571-579; doi: 10.1242/dmm.011833

  15. Musarò, Antonio

    1. Research Article
      A necrotic stimulus is required to maximize matrix-mediated myogenesis in mice
      Drew Kuraitis, Maria Grazia Berardinelli, Erik J. Suuronen, Antonio Musarò
      Disease Models & Mechanisms 2013 6: 793-801; doi: 10.1242/dmm.011072

N

  1. Nandra, Kiran K.

    1. Research Article
      Pharmacological preconditioning with erythropoietin attenuates the organ injury and dysfunction induced in a rat model of hemorrhagic shock
      Kiran K. Nandra, Massimo Collino, Mara Rogazzo, Roberto Fantozzi, Nimesh S. A. Patel, Christoph Thiemermann
      Disease Models & Mechanisms 2013 6: 701-709; doi: 10.1242/dmm.011353

  2. Neal, James T.

    1. Research Article
      H. pylori virulence factor CagA increases intestinal cell proliferation by Wnt pathway activation in a transgenic zebrafish model
      James T. Neal, Tracy S. Peterson, Michael L. Kent, Karen Guillemin
      Disease Models & Mechanisms 2013 6: 802-810; doi: 10.1242/dmm.011163

O

  1. Ochala, Julien

    1. Research Report
      The fraction of strongly bound cross-bridges is increased in mice that carry the myopathy-linked myosin heavy chain mutation MYH4L342Q
      Johan Lindqvist, Hiroyuki Iwamoto, Gonzalo Blanco, Julien Ochala
      Disease Models & Mechanisms 2013 6: 834-840; doi: 10.1242/dmm.011155

P

  1. Pallares, Judit

    1. Research Article
      An inducible knockout mouse to model the cell-autonomous role of PTEN in initiating endometrial, prostate and thyroid neoplasias
      Cristina Mirantes, Núria Eritja, Maria Alba Dosil, Maria Santacana, Judit Pallares, Sónia Gatius, Laura Bergadà, Oscar Maiques, Xavier Matias-Guiu, Xavier Dolcet
      Disease Models & Mechanisms 2013 6: 710-720; doi: 10.1242/dmm.011445

  2. Panaite, Petrica-Adrian

    1. Research Article
      Functional and histopathological identification of the respiratory failure in a DMSXL transgenic mouse model of myotonic dystrophy
      Petrica-Adrian Panaite, Thierry Kuntzer, Geneviève Gourdon, Johannes Alexander Lobrinus, Ibtissam Barakat-Walter
      Disease Models & Mechanisms 2013 6: 622-631; doi: 10.1242/dmm.010512

  3. Pandolfo, Massimo

    1. Research Article
      Neurons and cardiomyocytes derived from induced pluripotent stem cells as a model for mitochondrial defects in Friedreich’s ataxia
      Aurore Hick, Marie Wattenhofer-Donzé, Satyan Chintawar, Philippe Tropel, Jodie P. Simard, Nadège Vaucamps, David Gall, Laurie Lambot, Cécile André, Laurence Reutenauer, Myriam Rai, Marius Teletin, Nadia Messaddeq, Serge N. Schiffmann, Stéphane Viville, Christopher E. Pearson, Massimo Pandolfo, Hélène Puccio
      Disease Models & Mechanisms 2013 6: 608-621; doi: 10.1242/dmm.010900

  4. Pankratz, Talia

    1. Research Article
      From shape to cells: mouse models reveal mechanisms altering palate development in Apert syndrome
      Neus Martínez-Abadías, Greg Holmes, Talia Pankratz, Yingli Wang, Xueyan Zhou, Ethylin Wang Jabs, Joan T. Richtsmeier
      Disease Models & Mechanisms 2013 6: 768-779; doi: 10.1242/dmm.010397

  5. Paolella, Brenton R.

    1. Research Report
      Behavioral abnormalities and Parkinson’s-like histological changes resulting from Id2 inactivation in mice
      Matthew C. Havrda, Brenton R. Paolella, Nora M. Ward, Kathryn B. Holroyd
      Disease Models & Mechanisms 2013 6: 819-827; doi: 10.1242/dmm.010041

  6. Patel, Nimesh S. A.

    1. Research Article
      Pharmacological preconditioning with erythropoietin attenuates the organ injury and dysfunction induced in a rat model of hemorrhagic shock
      Kiran K. Nandra, Massimo Collino, Mara Rogazzo, Roberto Fantozzi, Nimesh S. A. Patel, Christoph Thiemermann
      Disease Models & Mechanisms 2013 6: 701-709; doi: 10.1242/dmm.011353

  7. Pauws, Erwin

    1. Special Article
      Bloomsbury report on mouse embryo phenotyping: recommendations from the IMPC workshop on embryonic lethal screening
      David Adams, Richard Baldock, Shoumo Bhattacharya, Andrew J. Copp, Mary Dickinson, Nicholas D. E. Greene, Mark Henkelman, Monica Justice, Timothy Mohun, Stephen A. Murray, Erwin Pauws, Michael Raess, Janet Rossant, Tom Weaver, David West
      Disease Models & Mechanisms 2013 6: 571-579; doi: 10.1242/dmm.011833

  8. Pearson, Christopher E.

    1. Research Article
      Neurons and cardiomyocytes derived from induced pluripotent stem cells as a model for mitochondrial defects in Friedreich’s ataxia
      Aurore Hick, Marie Wattenhofer-Donzé, Satyan Chintawar, Philippe Tropel, Jodie P. Simard, Nadège Vaucamps, David Gall, Laurie Lambot, Cécile André, Laurence Reutenauer, Myriam Rai, Marius Teletin, Nadia Messaddeq, Serge N. Schiffmann, Stéphane Viville, Christopher E. Pearson, Massimo Pandolfo, Hélène Puccio
      Disease Models & Mechanisms 2013 6: 608-621; doi: 10.1242/dmm.010900

  9. Peterson, Tracy S.

    1. Research Article
      H. pylori virulence factor CagA increases intestinal cell proliferation by Wnt pathway activation in a transgenic zebrafish model
      James T. Neal, Tracy S. Peterson, Michael L. Kent, Karen Guillemin
      Disease Models & Mechanisms 2013 6: 802-810; doi: 10.1242/dmm.011163

  10. Petzoldt, Astrid G.

    1. Research Article
      Elevated expression of the V-ATPase C subunit triggers JNK-dependent cell invasion and overgrowth in a Drosophila epithelium
      Astrid G. Petzoldt, Eva Maria Gleixner, Arianna Fumagalli, Thomas Vaccari, Matias Simons
      Disease Models & Mechanisms 2013 6: 689-700; doi: 10.1242/dmm.010660

  11. Pritz, Christian

    1. Research Article
      Sepsis otopathy: experimental sepsis leads to significant hearing impairment due to apoptosis and glutamate excitotoxicity in murine cochlea
      Joachim Schmutzhard, Rudolf Glueckert, Christian Pritz, Michael J. F. Blumer, Mario Bitsche, Peter Lackner, Manfred Fille, Herbert Riechelmann, Matthias Harkamp, Thongrong Sitthisak, Annelies Schrott-Fischer
      Disease Models & Mechanisms 2013 6: 745-754; doi: 10.1242/dmm.011205

  12. Puccio, Hélène

    1. Research Article
      Neurons and cardiomyocytes derived from induced pluripotent stem cells as a model for mitochondrial defects in Friedreich’s ataxia
      Aurore Hick, Marie Wattenhofer-Donzé, Satyan Chintawar, Philippe Tropel, Jodie P. Simard, Nadège Vaucamps, David Gall, Laurie Lambot, Cécile André, Laurence Reutenauer, Myriam Rai, Marius Teletin, Nadia Messaddeq, Serge N. Schiffmann, Stéphane Viville, Christopher E. Pearson, Massimo Pandolfo, Hélène Puccio
      Disease Models & Mechanisms 2013 6: 608-621; doi: 10.1242/dmm.010900

R

  1. Raess, Michael

    1. Special Article
      Bloomsbury report on mouse embryo phenotyping: recommendations from the IMPC workshop on embryonic lethal screening
      David Adams, Richard Baldock, Shoumo Bhattacharya, Andrew J. Copp, Mary Dickinson, Nicholas D. E. Greene, Mark Henkelman, Monica Justice, Timothy Mohun, Stephen A. Murray, Erwin Pauws, Michael Raess, Janet Rossant, Tom Weaver, David West
      Disease Models & Mechanisms 2013 6: 571-579; doi: 10.1242/dmm.011833

  2. Rai, Myriam

    1. Research Article
      Neurons and cardiomyocytes derived from induced pluripotent stem cells as a model for mitochondrial defects in Friedreich’s ataxia
      Aurore Hick, Marie Wattenhofer-Donzé, Satyan Chintawar, Philippe Tropel, Jodie P. Simard, Nadège Vaucamps, David Gall, Laurie Lambot, Cécile André, Laurence Reutenauer, Myriam Rai, Marius Teletin, Nadia Messaddeq, Serge N. Schiffmann, Stéphane Viville, Christopher E. Pearson, Massimo Pandolfo, Hélène Puccio
      Disease Models & Mechanisms 2013 6: 608-621; doi: 10.1242/dmm.010900

  3. Reutenauer, Laurence

    1. Research Article
      Neurons and cardiomyocytes derived from induced pluripotent stem cells as a model for mitochondrial defects in Friedreich’s ataxia
      Aurore Hick, Marie Wattenhofer-Donzé, Satyan Chintawar, Philippe Tropel, Jodie P. Simard, Nadège Vaucamps, David Gall, Laurie Lambot, Cécile André, Laurence Reutenauer, Myriam Rai, Marius Teletin, Nadia Messaddeq, Serge N. Schiffmann, Stéphane Viville, Christopher E. Pearson, Massimo Pandolfo, Hélène Puccio
      Disease Models & Mechanisms 2013 6: 608-621; doi: 10.1242/dmm.010900

  4. Richardson, Helena E.

    1. Research Article
      In Drosophila, RhoGEF2 cooperates with activated Ras in tumorigenesis through a pathway involving Rho1–Rok–Myosin-II and JNK signalling
      Peytee Khoo, Kirsten Allan, Lee Willoughby, Anthony M. Brumby, Helena E. Richardson
      Disease Models & Mechanisms 2013 6: 661-678; doi: 10.1242/dmm.010066

  5. Richtsmeier, Joan T.

    1. Research Article
      From shape to cells: mouse models reveal mechanisms altering palate development in Apert syndrome
      Neus Martínez-Abadías, Greg Holmes, Talia Pankratz, Yingli Wang, Xueyan Zhou, Ethylin Wang Jabs, Joan T. Richtsmeier
      Disease Models & Mechanisms 2013 6: 768-779; doi: 10.1242/dmm.010397

  6. Riechelmann, Herbert

    1. Research Article
      Sepsis otopathy: experimental sepsis leads to significant hearing impairment due to apoptosis and glutamate excitotoxicity in murine cochlea
      Joachim Schmutzhard, Rudolf Glueckert, Christian Pritz, Michael J. F. Blumer, Mario Bitsche, Peter Lackner, Manfred Fille, Herbert Riechelmann, Matthias Harkamp, Thongrong Sitthisak, Annelies Schrott-Fischer
      Disease Models & Mechanisms 2013 6: 745-754; doi: 10.1242/dmm.011205

  7. Robertson, Elizabeth

    1. Editorial
      Deciphering the Mechanisms of Developmental Disorders (DMDD): a new programme for phenotyping embryonic lethal mice
      Timothy Mohun, David J. Adams, Richard Baldock, Shoumo Bhattacharya, Andrew J. Copp, Myriam Hemberger, Corinne Houart, Matt E. Hurles, Elizabeth Robertson, James C. Smith, Tom Weaver, Wolfgang Weninger
      Disease Models & Mechanisms 2013 6: 562-566; doi: 10.1242/dmm.011957

  8. Rogazzo, Mara

    1. Research Article
      Pharmacological preconditioning with erythropoietin attenuates the organ injury and dysfunction induced in a rat model of hemorrhagic shock
      Kiran K. Nandra, Massimo Collino, Mara Rogazzo, Roberto Fantozzi, Nimesh S. A. Patel, Christoph Thiemermann
      Disease Models & Mechanisms 2013 6: 701-709; doi: 10.1242/dmm.011353

  9. Ross, Kristen D.

    1. Research Article
      Olfactomedin-1 activity identifies a cell invasion checkpoint during epithelial-mesenchymal transition in the chick embryonic heart
      Alejandro Lencinas, Danny C. Chhun, Kelvin P. Dan, Kristen D. Ross, Elizabeth A. Hoover, Parker B. Antin, Raymond B. Runyan
      Disease Models & Mechanisms 2013 6: 632-642; doi: 10.1242/dmm.010595

  10. Rossant, Janet

    1. Special Article
      Bloomsbury report on mouse embryo phenotyping: recommendations from the IMPC workshop on embryonic lethal screening
      David Adams, Richard Baldock, Shoumo Bhattacharya, Andrew J. Copp, Mary Dickinson, Nicholas D. E. Greene, Mark Henkelman, Monica Justice, Timothy Mohun, Stephen A. Murray, Erwin Pauws, Michael Raess, Janet Rossant, Tom Weaver, David West
      Disease Models & Mechanisms 2013 6: 571-579; doi: 10.1242/dmm.011833

  11. Runyan, Raymond B.

    1. Research Article
      Olfactomedin-1 activity identifies a cell invasion checkpoint during epithelial-mesenchymal transition in the chick embryonic heart
      Alejandro Lencinas, Danny C. Chhun, Kelvin P. Dan, Kristen D. Ross, Elizabeth A. Hoover, Parker B. Antin, Raymond B. Runyan
      Disease Models & Mechanisms 2013 6: 632-642; doi: 10.1242/dmm.010595

  12. Russell, Claire

    1. Research Article
      Generation and validation of a zebrafish model of EAST (epilepsy, ataxia, sensorineural deafness and tubulopathy) syndrome
      Fahad Mahmood, Monika Mozere, Anselm A. Zdebik, Horia C. Stanescu, Jonathan Tobin, Philip L. Beales, Robert Kleta, Detlef Bockenhauer, Claire Russell
      Disease Models & Mechanisms 2013 6: 652-660; doi: 10.1242/dmm.009480

S

  1. Sadaf, Sufia

    1. Research Article
      Altered lipid homeostasis in Drosophila InsP3 receptor mutants leads to obesity and hyperphagia
      Manivannan Subramanian, Suman Kumar Metya, Sufia Sadaf, Satish Kumar, Dominik Schwudke, Gaiti Hasan
      Disease Models & Mechanisms 2013 6: 734-744; doi: 10.1242/dmm.010017

  2. Samuels, Mark E.

    1. Research Article
      Loss of the E3 ubiquitin ligase LRSAM1 sensitizes peripheral axons to degeneration in a mouse model of Charcot-Marie-Tooth disease
      Laurent P. Bogdanik, James N. Sleigh, Cong Tian, Mark E. Samuels, Karen Bedard, Kevin L. Seburn, Robert W. Burgess
      Disease Models & Mechanisms 2013 6: 780-792; doi: 10.1242/dmm.010942

  3. Santacana, Maria

    1. Research Article
      An inducible knockout mouse to model the cell-autonomous role of PTEN in initiating endometrial, prostate and thyroid neoplasias
      Cristina Mirantes, Núria Eritja, Maria Alba Dosil, Maria Santacana, Judit Pallares, Sónia Gatius, Laura Bergadà, Oscar Maiques, Xavier Matias-Guiu, Xavier Dolcet
      Disease Models & Mechanisms 2013 6: 710-720; doi: 10.1242/dmm.011445

  4. Schiffmann, Serge N.

    1. Research Article
      Neurons and cardiomyocytes derived from induced pluripotent stem cells as a model for mitochondrial defects in Friedreich’s ataxia
      Aurore Hick, Marie Wattenhofer-Donzé, Satyan Chintawar, Philippe Tropel, Jodie P. Simard, Nadège Vaucamps, David Gall, Laurie Lambot, Cécile André, Laurence Reutenauer, Myriam Rai, Marius Teletin, Nadia Messaddeq, Serge N. Schiffmann, Stéphane Viville, Christopher E. Pearson, Massimo Pandolfo, Hélène Puccio
      Disease Models & Mechanisms 2013 6: 608-621; doi: 10.1242/dmm.010900

  5. Schmutzhard, Joachim

    1. Research Article
      Sepsis otopathy: experimental sepsis leads to significant hearing impairment due to apoptosis and glutamate excitotoxicity in murine cochlea
      Joachim Schmutzhard, Rudolf Glueckert, Christian Pritz, Michael J. F. Blumer, Mario Bitsche, Peter Lackner, Manfred Fille, Herbert Riechelmann, Matthias Harkamp, Thongrong Sitthisak, Annelies Schrott-Fischer
      Disease Models & Mechanisms 2013 6: 745-754; doi: 10.1242/dmm.011205

  6. Schrott-Fischer, Annelies

    1. Research Article
      Sepsis otopathy: experimental sepsis leads to significant hearing impairment due to apoptosis and glutamate excitotoxicity in murine cochlea
      Joachim Schmutzhard, Rudolf Glueckert, Christian Pritz, Michael J. F. Blumer, Mario Bitsche, Peter Lackner, Manfred Fille, Herbert Riechelmann, Matthias Harkamp, Thongrong Sitthisak, Annelies Schrott-Fischer
      Disease Models & Mechanisms 2013 6: 745-754; doi: 10.1242/dmm.011205

  7. Schwudke, Dominik

    1. Research Article
      Altered lipid homeostasis in Drosophila InsP3 receptor mutants leads to obesity and hyperphagia
      Manivannan Subramanian, Suman Kumar Metya, Sufia Sadaf, Satish Kumar, Dominik Schwudke, Gaiti Hasan
      Disease Models & Mechanisms 2013 6: 734-744; doi: 10.1242/dmm.010017

  8. Seburn, Kevin L.

    1. Research Article
      Loss of the E3 ubiquitin ligase LRSAM1 sensitizes peripheral axons to degeneration in a mouse model of Charcot-Marie-Tooth disease
      Laurent P. Bogdanik, James N. Sleigh, Cong Tian, Mark E. Samuels, Karen Bedard, Kevin L. Seburn, Robert W. Burgess
      Disease Models & Mechanisms 2013 6: 780-792; doi: 10.1242/dmm.010942

  9. Shah, Anand

    1. Research Article
      A new and clinically relevant murine model of solid-organ transplant aspergillosis
      Susanne Herbst, Anand Shah, Martin Carby, Gary Chusney, Naresh Kikkeri, Anthony Dorling, Elaine Bignell, Sunil Shaunak, Darius Armstrong-James
      Disease Models & Mechanisms 2013 6: 643-651; doi: 10.1242/dmm.010330

  10. Shaunak, Sunil

    1. Research Article
      A new and clinically relevant murine model of solid-organ transplant aspergillosis
      Susanne Herbst, Anand Shah, Martin Carby, Gary Chusney, Naresh Kikkeri, Anthony Dorling, Elaine Bignell, Sunil Shaunak, Darius Armstrong-James
      Disease Models & Mechanisms 2013 6: 643-651; doi: 10.1242/dmm.010330

  11. Shekhani, Mohammed T.

    1. Research Article
      Osteoarticular tissue infection and development of skeletal pathology in murine brucellosis
      Diogo M. Magnani, Elizabeth T. Lyons, Toni S. Forde, Mohammed T. Shekhani, Vyacheslav A. Adarichev, Gary A. Splitter
      Disease Models & Mechanisms 2013 6: 811-818; doi: 10.1242/dmm.011056

  12. Siegel, Vivian

    1. Editorial
      Provoking progress: a new chapter
      Vivian Siegel Founding Editor-in-Chief
      Disease Models & Mechanisms 2013 6: 557-558; doi: 10.1242/dmm.012419

  13. Simard, Jodie P.

    1. Research Article
      Neurons and cardiomyocytes derived from induced pluripotent stem cells as a model for mitochondrial defects in Friedreich’s ataxia
      Aurore Hick, Marie Wattenhofer-Donzé, Satyan Chintawar, Philippe Tropel, Jodie P. Simard, Nadège Vaucamps, David Gall, Laurie Lambot, Cécile André, Laurence Reutenauer, Myriam Rai, Marius Teletin, Nadia Messaddeq, Serge N. Schiffmann, Stéphane Viville, Christopher E. Pearson, Massimo Pandolfo, Hélène Puccio
      Disease Models & Mechanisms 2013 6: 608-621; doi: 10.1242/dmm.010900

  14. Simons, Matias

    1. Research Article
      Elevated expression of the V-ATPase C subunit triggers JNK-dependent cell invasion and overgrowth in a Drosophila epithelium
      Astrid G. Petzoldt, Eva Maria Gleixner, Arianna Fumagalli, Thomas Vaccari, Matias Simons
      Disease Models & Mechanisms 2013 6: 689-700; doi: 10.1242/dmm.010660

  15. Sitthisak, Thongrong

    1. Research Article
      Sepsis otopathy: experimental sepsis leads to significant hearing impairment due to apoptosis and glutamate excitotoxicity in murine cochlea
      Joachim Schmutzhard, Rudolf Glueckert, Christian Pritz, Michael J. F. Blumer, Mario Bitsche, Peter Lackner, Manfred Fille, Herbert Riechelmann, Matthias Harkamp, Thongrong Sitthisak, Annelies Schrott-Fischer
      Disease Models & Mechanisms 2013 6: 745-754; doi: 10.1242/dmm.011205

  16. Sleigh, James N.

    1. Research Article
      Loss of the E3 ubiquitin ligase LRSAM1 sensitizes peripheral axons to degeneration in a mouse model of Charcot-Marie-Tooth disease
      Laurent P. Bogdanik, James N. Sleigh, Cong Tian, Mark E. Samuels, Karen Bedard, Kevin L. Seburn, Robert W. Burgess
      Disease Models & Mechanisms 2013 6: 780-792; doi: 10.1242/dmm.010942

  17. Slusarski, Diane C.

    1. Research Article
      Mechanisms of prickle1a function in zebrafish epilepsy and retinal neurogenesis
      Xue Mei, Shu Wu, Alexander G. Bassuk, Diane C. Slusarski
      Disease Models & Mechanisms 2013 6: 679-688; doi: 10.1242/dmm.010793

  18. Smith, James C.

    1. Editorial
      Deciphering the Mechanisms of Developmental Disorders (DMDD): a new programme for phenotyping embryonic lethal mice
      Timothy Mohun, David J. Adams, Richard Baldock, Shoumo Bhattacharya, Andrew J. Copp, Myriam Hemberger, Corinne Houart, Matt E. Hurles, Elizabeth Robertson, James C. Smith, Tom Weaver, Wolfgang Weninger
      Disease Models & Mechanisms 2013 6: 562-566; doi: 10.1242/dmm.011957

  19. Spaink, Herman P.

    1. Resource Article
      Functional analysis of a zebrafish myd88 mutant identifies key transcriptional components of the innate immune system
      Michiel van der Vaart, Joost J. van Soest, Herman P. Spaink, Annemarie H. Meijer
      Disease Models & Mechanisms 2013 6: 841-854; doi: 10.1242/dmm.010843

  20. Splitter, Gary A.

    1. Research Article
      Osteoarticular tissue infection and development of skeletal pathology in murine brucellosis
      Diogo M. Magnani, Elizabeth T. Lyons, Toni S. Forde, Mohammed T. Shekhani, Vyacheslav A. Adarichev, Gary A. Splitter
      Disease Models & Mechanisms 2013 6: 811-818; doi: 10.1242/dmm.011056

  21. Stanescu, Horia C.

    1. Research Article
      Generation and validation of a zebrafish model of EAST (epilepsy, ataxia, sensorineural deafness and tubulopathy) syndrome
      Fahad Mahmood, Monika Mozere, Anselm A. Zdebik, Horia C. Stanescu, Jonathan Tobin, Philip L. Beales, Robert Kleta, Detlef Bockenhauer, Claire Russell
      Disease Models & Mechanisms 2013 6: 652-660; doi: 10.1242/dmm.009480

  22. Subramanian, Manivannan

    1. Research Article
      Altered lipid homeostasis in Drosophila InsP3 receptor mutants leads to obesity and hyperphagia
      Manivannan Subramanian, Suman Kumar Metya, Sufia Sadaf, Satish Kumar, Dominik Schwudke, Gaiti Hasan
      Disease Models & Mechanisms 2013 6: 734-744; doi: 10.1242/dmm.010017

  23. Sukhina, Alona S.

    1. Research Article
      Motor neurons and glia exhibit specific individualized responses to TDP-43 expression in a Drosophila model of amyotrophic lateral sclerosis
      Patricia S. Estes, Scott G. Daniel, Abigail P. Mccallum, Ashley V. Boehringer, Alona S. Sukhina, Rebecca A. Zwick, Daniela C. Zarnescu
      Disease Models & Mechanisms 2013 6: 721-733; doi: 10.1242/dmm.010710

  24. Suuronen, Erik J.

    1. Research Article
      A necrotic stimulus is required to maximize matrix-mediated myogenesis in mice
      Drew Kuraitis, Maria Grazia Berardinelli, Erik J. Suuronen, Antonio Musarò
      Disease Models & Mechanisms 2013 6: 793-801; doi: 10.1242/dmm.011072

T

  1. Teletin, Marius

    1. Research Article
      Neurons and cardiomyocytes derived from induced pluripotent stem cells as a model for mitochondrial defects in Friedreich’s ataxia
      Aurore Hick, Marie Wattenhofer-Donzé, Satyan Chintawar, Philippe Tropel, Jodie P. Simard, Nadège Vaucamps, David Gall, Laurie Lambot, Cécile André, Laurence Reutenauer, Myriam Rai, Marius Teletin, Nadia Messaddeq, Serge N. Schiffmann, Stéphane Viville, Christopher E. Pearson, Massimo Pandolfo, Hélène Puccio
      Disease Models & Mechanisms 2013 6: 608-621; doi: 10.1242/dmm.010900

  2. Thiemermann, Christoph

    1. Research Article
      Pharmacological preconditioning with erythropoietin attenuates the organ injury and dysfunction induced in a rat model of hemorrhagic shock
      Kiran K. Nandra, Massimo Collino, Mara Rogazzo, Roberto Fantozzi, Nimesh S. A. Patel, Christoph Thiemermann
      Disease Models & Mechanisms 2013 6: 701-709; doi: 10.1242/dmm.011353

  3. Thompson, Amelia J.

    1. Research Article
      A murine Zic3 transcript with a premature termination codon evades nonsense-mediated decay during axis formation
      Jehangir N. Ahmed, Radiya G. Ali, Nicholas Warr, Heather M. Wilson, Helen M. Bellchambers, Kristen S. Barratt, Amelia J. Thompson, Ruth M. Arkell
      Disease Models & Mechanisms 2013 6: 755-767; doi: 10.1242/dmm.011668

  4. Tian, Cong

    1. Research Article
      Loss of the E3 ubiquitin ligase LRSAM1 sensitizes peripheral axons to degeneration in a mouse model of Charcot-Marie-Tooth disease
      Laurent P. Bogdanik, James N. Sleigh, Cong Tian, Mark E. Samuels, Karen Bedard, Kevin L. Seburn, Robert W. Burgess
      Disease Models & Mechanisms 2013 6: 780-792; doi: 10.1242/dmm.010942

  5. Tidmarsh, George F.

    1. Editorial
      Bridging the gap between basic and applied biology: towards preclinical translation
      Ross L. Cagan, Monica J. Justice, George F. Tidmarsh
      Disease Models & Mechanisms 2013 6: 559-561; doi: 10.1242/dmm.012450

  6. Tobin, Jonathan

    1. Research Article
      Generation and validation of a zebrafish model of EAST (epilepsy, ataxia, sensorineural deafness and tubulopathy) syndrome
      Fahad Mahmood, Monika Mozere, Anselm A. Zdebik, Horia C. Stanescu, Jonathan Tobin, Philip L. Beales, Robert Kleta, Detlef Bockenhauer, Claire Russell
      Disease Models & Mechanisms 2013 6: 652-660; doi: 10.1242/dmm.009480

  7. Tropel, Philippe

    1. Research Article
      Neurons and cardiomyocytes derived from induced pluripotent stem cells as a model for mitochondrial defects in Friedreich’s ataxia
      Aurore Hick, Marie Wattenhofer-Donzé, Satyan Chintawar, Philippe Tropel, Jodie P. Simard, Nadège Vaucamps, David Gall, Laurie Lambot, Cécile André, Laurence Reutenauer, Myriam Rai, Marius Teletin, Nadia Messaddeq, Serge N. Schiffmann, Stéphane Viville, Christopher E. Pearson, Massimo Pandolfo, Hélène Puccio
      Disease Models & Mechanisms 2013 6: 608-621; doi: 10.1242/dmm.010900

V

  1. Vaccari, Thomas

    1. Research Article
      Elevated expression of the V-ATPase C subunit triggers JNK-dependent cell invasion and overgrowth in a Drosophila epithelium
      Astrid G. Petzoldt, Eva Maria Gleixner, Arianna Fumagalli, Thomas Vaccari, Matias Simons
      Disease Models & Mechanisms 2013 6: 689-700; doi: 10.1242/dmm.010660

  2. van der Vaart, Michiel

    1. Resource Article
      Functional analysis of a zebrafish myd88 mutant identifies key transcriptional components of the innate immune system
      Michiel van der Vaart, Joost J. van Soest, Herman P. Spaink, Annemarie H. Meijer
      Disease Models & Mechanisms 2013 6: 841-854; doi: 10.1242/dmm.010843

  3. van Soest, Joost J.

    1. Resource Article
      Functional analysis of a zebrafish myd88 mutant identifies key transcriptional components of the innate immune system
      Michiel van der Vaart, Joost J. van Soest, Herman P. Spaink, Annemarie H. Meijer
      Disease Models & Mechanisms 2013 6: 841-854; doi: 10.1242/dmm.010843

  4. Vaucamps, Nadège

    1. Research Article
      Neurons and cardiomyocytes derived from induced pluripotent stem cells as a model for mitochondrial defects in Friedreich’s ataxia
      Aurore Hick, Marie Wattenhofer-Donzé, Satyan Chintawar, Philippe Tropel, Jodie P. Simard, Nadège Vaucamps, David Gall, Laurie Lambot, Cécile André, Laurence Reutenauer, Myriam Rai, Marius Teletin, Nadia Messaddeq, Serge N. Schiffmann, Stéphane Viville, Christopher E. Pearson, Massimo Pandolfo, Hélène Puccio
      Disease Models & Mechanisms 2013 6: 608-621; doi: 10.1242/dmm.010900

  5. Viville, Stéphane

    1. Research Article
      Neurons and cardiomyocytes derived from induced pluripotent stem cells as a model for mitochondrial defects in Friedreich’s ataxia
      Aurore Hick, Marie Wattenhofer-Donzé, Satyan Chintawar, Philippe Tropel, Jodie P. Simard, Nadège Vaucamps, David Gall, Laurie Lambot, Cécile André, Laurence Reutenauer, Myriam Rai, Marius Teletin, Nadia Messaddeq, Serge N. Schiffmann, Stéphane Viville, Christopher E. Pearson, Massimo Pandolfo, Hélène Puccio
      Disease Models & Mechanisms 2013 6: 608-621; doi: 10.1242/dmm.010900

W

  1. Wang, Xiaoting

    1. Resource Article
      An entirely automated method to score DSS-induced colitis in mice by digital image analysis of pathology slides
      Cleopatra Kozlowski, Surinder Jeet, Joseph Beyer, Steve Guerrero, Justin Lesch, Xiaoting Wang, Jason DeVoss, Lauri Diehl
      Disease Models & Mechanisms 2013 6: 855-865; doi: 10.1242/dmm.011759

  2. Wang, Yingli

    1. Research Article
      From shape to cells: mouse models reveal mechanisms altering palate development in Apert syndrome
      Neus Martínez-Abadías, Greg Holmes, Talia Pankratz, Yingli Wang, Xueyan Zhou, Ethylin Wang Jabs, Joan T. Richtsmeier
      Disease Models & Mechanisms 2013 6: 768-779; doi: 10.1242/dmm.010397

  3. Ward, Nora M.

    1. Research Report
      Behavioral abnormalities and Parkinson’s-like histological changes resulting from Id2 inactivation in mice
      Matthew C. Havrda, Brenton R. Paolella, Nora M. Ward, Kathryn B. Holroyd
      Disease Models & Mechanisms 2013 6: 819-827; doi: 10.1242/dmm.010041

  4. Warr, Nicholas

    1. Research Article
      A murine Zic3 transcript with a premature termination codon evades nonsense-mediated decay during axis formation
      Jehangir N. Ahmed, Radiya G. Ali, Nicholas Warr, Heather M. Wilson, Helen M. Bellchambers, Kristen S. Barratt, Amelia J. Thompson, Ruth M. Arkell
      Disease Models & Mechanisms 2013 6: 755-767; doi: 10.1242/dmm.011668

  5. Wattenhofer-Donzé, Marie

    1. Research Article
      Neurons and cardiomyocytes derived from induced pluripotent stem cells as a model for mitochondrial defects in Friedreich’s ataxia
      Aurore Hick, Marie Wattenhofer-Donzé, Satyan Chintawar, Philippe Tropel, Jodie P. Simard, Nadège Vaucamps, David Gall, Laurie Lambot, Cécile André, Laurence Reutenauer, Myriam Rai, Marius Teletin, Nadia Messaddeq, Serge N. Schiffmann, Stéphane Viville, Christopher E. Pearson, Massimo Pandolfo, Hélène Puccio
      Disease Models & Mechanisms 2013 6: 608-621; doi: 10.1242/dmm.010900

  6. Weaver, Tom

    1. Editorial
      Deciphering the Mechanisms of Developmental Disorders (DMDD): a new programme for phenotyping embryonic lethal mice
      Timothy Mohun, David J. Adams, Richard Baldock, Shoumo Bhattacharya, Andrew J. Copp, Myriam Hemberger, Corinne Houart, Matt E. Hurles, Elizabeth Robertson, James C. Smith, Tom Weaver, Wolfgang Weninger
      Disease Models & Mechanisms 2013 6: 562-566; doi: 10.1242/dmm.011957
    2. Special Article
      Bloomsbury report on mouse embryo phenotyping: recommendations from the IMPC workshop on embryonic lethal screening
      David Adams, Richard Baldock, Shoumo Bhattacharya, Andrew J. Copp, Mary Dickinson, Nicholas D. E. Greene, Mark Henkelman, Monica Justice, Timothy Mohun, Stephen A. Murray, Erwin Pauws, Michael Raess, Janet Rossant, Tom Weaver, David West
      Disease Models & Mechanisms 2013 6: 571-579; doi: 10.1242/dmm.011833

  7. Weninger, Wolfgang

    1. Editorial
      Deciphering the Mechanisms of Developmental Disorders (DMDD): a new programme for phenotyping embryonic lethal mice
      Timothy Mohun, David J. Adams, Richard Baldock, Shoumo Bhattacharya, Andrew J. Copp, Myriam Hemberger, Corinne Houart, Matt E. Hurles, Elizabeth Robertson, James C. Smith, Tom Weaver, Wolfgang Weninger
      Disease Models & Mechanisms 2013 6: 562-566; doi: 10.1242/dmm.011957

  8. West, David

    1. Special Article
      Bloomsbury report on mouse embryo phenotyping: recommendations from the IMPC workshop on embryonic lethal screening
      David Adams, Richard Baldock, Shoumo Bhattacharya, Andrew J. Copp, Mary Dickinson, Nicholas D. E. Greene, Mark Henkelman, Monica Justice, Timothy Mohun, Stephen A. Murray, Erwin Pauws, Michael Raess, Janet Rossant, Tom Weaver, David West
      Disease Models & Mechanisms 2013 6: 571-579; doi: 10.1242/dmm.011833

  9. Willoughby, Lee

    1. Research Article
      In Drosophila, RhoGEF2 cooperates with activated Ras in tumorigenesis through a pathway involving Rho1–Rok–Myosin-II and JNK signalling
      Peytee Khoo, Kirsten Allan, Lee Willoughby, Anthony M. Brumby, Helena E. Richardson
      Disease Models & Mechanisms 2013 6: 661-678; doi: 10.1242/dmm.010066

  10. Wilson, Heather M.

    1. Research Article
      A murine Zic3 transcript with a premature termination codon evades nonsense-mediated decay during axis formation
      Jehangir N. Ahmed, Radiya G. Ali, Nicholas Warr, Heather M. Wilson, Helen M. Bellchambers, Kristen S. Barratt, Amelia J. Thompson, Ruth M. Arkell
      Disease Models & Mechanisms 2013 6: 755-767; doi: 10.1242/dmm.011668

  11. Wu, Shu

    1. Research Article
      Mechanisms of prickle1a function in zebrafish epilepsy and retinal neurogenesis
      Xue Mei, Shu Wu, Alexander G. Bassuk, Diane C. Slusarski
      Disease Models & Mechanisms 2013 6: 679-688; doi: 10.1242/dmm.010793

  12. Wu, Xiaohui

    1. Research Report
      piggyBac as a high-capacity transgenesis and gene-therapy vector in human cells and mice
      Rongbo Li, Yuan Zhuang, Min Han, Tian Xu, Xiaohui Wu
      Disease Models & Mechanisms 2013 6: 828-833; doi: 10.1242/dmm.010827

X

  1. Xu, Tian

    1. Research Report
      piggyBac as a high-capacity transgenesis and gene-therapy vector in human cells and mice
      Rongbo Li, Yuan Zhuang, Min Han, Tian Xu, Xiaohui Wu
      Disease Models & Mechanisms 2013 6: 828-833; doi: 10.1242/dmm.010827

Z

  1. Zarnescu, Daniela C.

    1. Research Article
      Motor neurons and glia exhibit specific individualized responses to TDP-43 expression in a Drosophila model of amyotrophic lateral sclerosis
      Patricia S. Estes, Scott G. Daniel, Abigail P. Mccallum, Ashley V. Boehringer, Alona S. Sukhina, Rebecca A. Zwick, Daniela C. Zarnescu
      Disease Models & Mechanisms 2013 6: 721-733; doi: 10.1242/dmm.010710

  2. Zdebik, Anselm A.

    1. Research Article
      Generation and validation of a zebrafish model of EAST (epilepsy, ataxia, sensorineural deafness and tubulopathy) syndrome
      Fahad Mahmood, Monika Mozere, Anselm A. Zdebik, Horia C. Stanescu, Jonathan Tobin, Philip L. Beales, Robert Kleta, Detlef Bockenhauer, Claire Russell
      Disease Models & Mechanisms 2013 6: 652-660; doi: 10.1242/dmm.009480

  3. Zhou, Xueyan

    1. Research Article
      From shape to cells: mouse models reveal mechanisms altering palate development in Apert syndrome
      Neus Martínez-Abadías, Greg Holmes, Talia Pankratz, Yingli Wang, Xueyan Zhou, Ethylin Wang Jabs, Joan T. Richtsmeier
      Disease Models & Mechanisms 2013 6: 768-779; doi: 10.1242/dmm.010397

  4. Zhuang, Yuan

    1. Research Report
      piggyBac as a high-capacity transgenesis and gene-therapy vector in human cells and mice
      Rongbo Li, Yuan Zhuang, Min Han, Tian Xu, Xiaohui Wu
      Disease Models & Mechanisms 2013 6: 828-833; doi: 10.1242/dmm.010827

  5. Zwick, Rebecca A.

    1. Research Article
      Motor neurons and glia exhibit specific individualized responses to TDP-43 expression in a Drosophila model of amyotrophic lateral sclerosis
      Patricia S. Estes, Scott G. Daniel, Abigail P. Mccallum, Ashley V. Boehringer, Alona S. Sukhina, Rebecca A. Zwick, Daniela C. Zarnescu
      Disease Models & Mechanisms 2013 6: 721-733; doi: 10.1242/dmm.010710
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DMM and COVID-19

We are aware that the COVID-19 pandemic is having an unprecedented impact on researchers worldwide. The Editors of all The Company of Biologists’ journals have been considering ways in which we can alleviate concerns that members of our community may have around publishing activities during this time. Read about the actions we are taking at this time.

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Alessandro Bailetti is awarded the DMM Outstanding Paper Prize 2019

The annual prize is awarded to the first author of the paper that is judged by the journal’s editors to be the most outstanding contribution to the journal that year. Alessandro Bailetti's winning paper presents results that indicate a possible connection between E(Pc) and the Tip60 complex, and leukemia. Find out more about Alessandro and read the winning paper.

Find DMM online

We may not be meeting you in person this year, but we’re always here to chat about DMM and The Company of Biologists. Join the conversation over on Twitter, email us or catch Scientific Editor Julija Hmeljak at these upcoming virtual meetings:

MRC Human Genetics Unit (Virtual) Symposium: Aberrant Cell State Transitions in Human Disease
23-24 September

Genomic Imprinting – from Biology to Disease
28 September – 1 October

ZDMS Virtual webinar series
Throughout September – December

Interview - Mohd. Salman

First author Mohd. Salman studies traumatic brain injury. In an interview, he takes us through his latest research in DMM, explaining the potential implications of the findings, and discussing Wistar rats as a model system and life as a early-career researcher. 

Call for papers - The RAS Pathway: Diseases, Therapeutics and Beyond

DMM invites you to submit original research for a special issue focused on targeting the RAS pathway. The submission deadline is 1 March 2021. Find out more and showcase your breakthrough research in this special collection. 

It’s a time of turmoil for young scientists

“My students are my priority – they are on the brink of their careers.”

Dr Jodie Rummer (ARC Centre of Excellence for Coral Reef Studies at James Cook University) talks about the importance of her role as a supervisor in supporting graduate students and post docs financially, intellectually and emotionally during this period of uncertainty.