A
Adams, David
- Special ArticleBloomsbury report on mouse embryo phenotyping: recommendations from the IMPC workshop on embryonic lethal screeningDavid Adams, Richard Baldock, Shoumo Bhattacharya, Andrew J. Copp, Mary Dickinson, Nicholas D. E. Greene, Mark Henkelman, Monica Justice, Timothy Mohun, Stephen A. Murray, Erwin Pauws, Michael Raess, Janet Rossant, Tom Weaver, David WestDisease Models & Mechanisms 2013 6: 571-579; doi: 10.1242/dmm.011833
Adams, David J.
- EditorialDeciphering the Mechanisms of Developmental Disorders (DMDD): a new programme for phenotyping embryonic lethal miceTimothy Mohun, David J. Adams, Richard Baldock, Shoumo Bhattacharya, Andrew J. Copp, Myriam Hemberger, Corinne Houart, Matt E. Hurles, Elizabeth Robertson, James C. Smith, Tom Weaver, Wolfgang WeningerDisease Models & Mechanisms 2013 6: 562-566; doi: 10.1242/dmm.011957
Adarichev, Vyacheslav A.
- Research ArticleOsteoarticular tissue infection and development of skeletal pathology in murine brucellosisDiogo M. Magnani, Elizabeth T. Lyons, Toni S. Forde, Mohammed T. Shekhani, Vyacheslav A. Adarichev, Gary A. SplitterDisease Models & Mechanisms 2013 6: 811-818; doi: 10.1242/dmm.011056
Ahmed, Jehangir N.
- Research ArticleA murine Zic3 transcript with a premature termination codon evades nonsense-mediated decay during axis formationJehangir N. Ahmed, Radiya G. Ali, Nicholas Warr, Heather M. Wilson, Helen M. Bellchambers, Kristen S. Barratt, Amelia J. Thompson, Ruth M. ArkellDisease Models & Mechanisms 2013 6: 755-767; doi: 10.1242/dmm.011668
Ali, Radiya G.
- Research ArticleA murine Zic3 transcript with a premature termination codon evades nonsense-mediated decay during axis formationJehangir N. Ahmed, Radiya G. Ali, Nicholas Warr, Heather M. Wilson, Helen M. Bellchambers, Kristen S. Barratt, Amelia J. Thompson, Ruth M. ArkellDisease Models & Mechanisms 2013 6: 755-767; doi: 10.1242/dmm.011668
Allan, Kirsten
- Research ArticleIn Drosophila, RhoGEF2 cooperates with activated Ras in tumorigenesis through a pathway involving Rho1–Rok–Myosin-II and JNK signallingPeytee Khoo, Kirsten Allan, Lee Willoughby, Anthony M. Brumby, Helena E. RichardsonDisease Models & Mechanisms 2013 6: 661-678; doi: 10.1242/dmm.010066
André, Cécile
- Research ArticleNeurons and cardiomyocytes derived from induced pluripotent stem cells as a model for mitochondrial defects in Friedreich’s ataxiaAurore Hick, Marie Wattenhofer-Donzé, Satyan Chintawar, Philippe Tropel, Jodie P. Simard, Nadège Vaucamps, David Gall, Laurie Lambot, Cécile André, Laurence Reutenauer, Myriam Rai, Marius Teletin, Nadia Messaddeq, Serge N. Schiffmann, Stéphane Viville, Christopher E. Pearson, Massimo Pandolfo, Hélène PuccioDisease Models & Mechanisms 2013 6: 608-621; doi: 10.1242/dmm.010900
Antin, Parker B.
- Research ArticleOlfactomedin-1 activity identifies a cell invasion checkpoint during epithelial-mesenchymal transition in the chick embryonic heartAlejandro Lencinas, Danny C. Chhun, Kelvin P. Dan, Kristen D. Ross, Elizabeth A. Hoover, Parker B. Antin, Raymond B. RunyanDisease Models & Mechanisms 2013 6: 632-642; doi: 10.1242/dmm.010595
Arkell, Ruth M.
- Research ArticleA murine Zic3 transcript with a premature termination codon evades nonsense-mediated decay during axis formationJehangir N. Ahmed, Radiya G. Ali, Nicholas Warr, Heather M. Wilson, Helen M. Bellchambers, Kristen S. Barratt, Amelia J. Thompson, Ruth M. ArkellDisease Models & Mechanisms 2013 6: 755-767; doi: 10.1242/dmm.011668
Armstrong-James, Darius
- Research ArticleA new and clinically relevant murine model of solid-organ transplant aspergillosisSusanne Herbst, Anand Shah, Martin Carby, Gary Chusney, Naresh Kikkeri, Anthony Dorling, Elaine Bignell, Sunil Shaunak, Darius Armstrong-JamesDisease Models & Mechanisms 2013 6: 643-651; doi: 10.1242/dmm.010330
B
Baldock, Richard
- EditorialDeciphering the Mechanisms of Developmental Disorders (DMDD): a new programme for phenotyping embryonic lethal miceTimothy Mohun, David J. Adams, Richard Baldock, Shoumo Bhattacharya, Andrew J. Copp, Myriam Hemberger, Corinne Houart, Matt E. Hurles, Elizabeth Robertson, James C. Smith, Tom Weaver, Wolfgang WeningerDisease Models & Mechanisms 2013 6: 562-566; doi: 10.1242/dmm.011957
- Special ArticleBloomsbury report on mouse embryo phenotyping: recommendations from the IMPC workshop on embryonic lethal screeningDavid Adams, Richard Baldock, Shoumo Bhattacharya, Andrew J. Copp, Mary Dickinson, Nicholas D. E. Greene, Mark Henkelman, Monica Justice, Timothy Mohun, Stephen A. Murray, Erwin Pauws, Michael Raess, Janet Rossant, Tom Weaver, David WestDisease Models & Mechanisms 2013 6: 571-579; doi: 10.1242/dmm.011833
Barakat-Walter, Ibtissam
- Research ArticleFunctional and histopathological identification of the respiratory failure in a DMSXL transgenic mouse model of myotonic dystrophyPetrica-Adrian Panaite, Thierry Kuntzer, Geneviève Gourdon, Johannes Alexander Lobrinus, Ibtissam Barakat-WalterDisease Models & Mechanisms 2013 6: 622-631; doi: 10.1242/dmm.010512
Barratt, Kristen S.
- Research ArticleA murine Zic3 transcript with a premature termination codon evades nonsense-mediated decay during axis formationJehangir N. Ahmed, Radiya G. Ali, Nicholas Warr, Heather M. Wilson, Helen M. Bellchambers, Kristen S. Barratt, Amelia J. Thompson, Ruth M. ArkellDisease Models & Mechanisms 2013 6: 755-767; doi: 10.1242/dmm.011668
Bassuk, Alexander G.
- Research ArticleMechanisms of prickle1a function in zebrafish epilepsy and retinal neurogenesisXue Mei, Shu Wu, Alexander G. Bassuk, Diane C. SlusarskiDisease Models & Mechanisms 2013 6: 679-688; doi: 10.1242/dmm.010793
Beales, Philip L.
- Research ArticleGeneration and validation of a zebrafish model of EAST (epilepsy, ataxia, sensorineural deafness and tubulopathy) syndromeFahad Mahmood, Monika Mozere, Anselm A. Zdebik, Horia C. Stanescu, Jonathan Tobin, Philip L. Beales, Robert Kleta, Detlef Bockenhauer, Claire RussellDisease Models & Mechanisms 2013 6: 652-660; doi: 10.1242/dmm.009480
Bedard, Karen
- Research ArticleLoss of the E3 ubiquitin ligase LRSAM1 sensitizes peripheral axons to degeneration in a mouse model of Charcot-Marie-Tooth diseaseLaurent P. Bogdanik, James N. Sleigh, Cong Tian, Mark E. Samuels, Karen Bedard, Kevin L. Seburn, Robert W. BurgessDisease Models & Mechanisms 2013 6: 780-792; doi: 10.1242/dmm.010942
Bellchambers, Helen M.
- Research ArticleA murine Zic3 transcript with a premature termination codon evades nonsense-mediated decay during axis formationJehangir N. Ahmed, Radiya G. Ali, Nicholas Warr, Heather M. Wilson, Helen M. Bellchambers, Kristen S. Barratt, Amelia J. Thompson, Ruth M. ArkellDisease Models & Mechanisms 2013 6: 755-767; doi: 10.1242/dmm.011668
Berardinelli, Maria Grazia
- Research ArticleA necrotic stimulus is required to maximize matrix-mediated myogenesis in miceDrew Kuraitis, Maria Grazia Berardinelli, Erik J. Suuronen, Antonio MusaròDisease Models & Mechanisms 2013 6: 793-801; doi: 10.1242/dmm.011072
Bergadà, Laura
- Research ArticleAn inducible knockout mouse to model the cell-autonomous role of PTEN in initiating endometrial, prostate and thyroid neoplasiasCristina Mirantes, Núria Eritja, Maria Alba Dosil, Maria Santacana, Judit Pallares, Sónia Gatius, Laura Bergadà, Oscar Maiques, Xavier Matias-Guiu, Xavier DolcetDisease Models & Mechanisms 2013 6: 710-720; doi: 10.1242/dmm.011445
Beyer, Joseph
- Resource ArticleAn entirely automated method to score DSS-induced colitis in mice by digital image analysis of pathology slidesCleopatra Kozlowski, Surinder Jeet, Joseph Beyer, Steve Guerrero, Justin Lesch, Xiaoting Wang, Jason DeVoss, Lauri DiehlDisease Models & Mechanisms 2013 6: 855-865; doi: 10.1242/dmm.011759
Bhattacharya, Shoumo
- EditorialDeciphering the Mechanisms of Developmental Disorders (DMDD): a new programme for phenotyping embryonic lethal miceTimothy Mohun, David J. Adams, Richard Baldock, Shoumo Bhattacharya, Andrew J. Copp, Myriam Hemberger, Corinne Houart, Matt E. Hurles, Elizabeth Robertson, James C. Smith, Tom Weaver, Wolfgang WeningerDisease Models & Mechanisms 2013 6: 562-566; doi: 10.1242/dmm.011957
- Special ArticleBloomsbury report on mouse embryo phenotyping: recommendations from the IMPC workshop on embryonic lethal screeningDavid Adams, Richard Baldock, Shoumo Bhattacharya, Andrew J. Copp, Mary Dickinson, Nicholas D. E. Greene, Mark Henkelman, Monica Justice, Timothy Mohun, Stephen A. Murray, Erwin Pauws, Michael Raess, Janet Rossant, Tom Weaver, David WestDisease Models & Mechanisms 2013 6: 571-579; doi: 10.1242/dmm.011833
Bignell, Elaine
- Research ArticleA new and clinically relevant murine model of solid-organ transplant aspergillosisSusanne Herbst, Anand Shah, Martin Carby, Gary Chusney, Naresh Kikkeri, Anthony Dorling, Elaine Bignell, Sunil Shaunak, Darius Armstrong-JamesDisease Models & Mechanisms 2013 6: 643-651; doi: 10.1242/dmm.010330
Bitsche, Mario
- Research ArticleSepsis otopathy: experimental sepsis leads to significant hearing impairment due to apoptosis and glutamate excitotoxicity in murine cochleaJoachim Schmutzhard, Rudolf Glueckert, Christian Pritz, Michael J. F. Blumer, Mario Bitsche, Peter Lackner, Manfred Fille, Herbert Riechelmann, Matthias Harkamp, Thongrong Sitthisak, Annelies Schrott-FischerDisease Models & Mechanisms 2013 6: 745-754; doi: 10.1242/dmm.011205
Blanco, Gonzalo
- Research ReportThe fraction of strongly bound cross-bridges is increased in mice that carry the myopathy-linked myosin heavy chain mutation MYH4L342QJohan Lindqvist, Hiroyuki Iwamoto, Gonzalo Blanco, Julien OchalaDisease Models & Mechanisms 2013 6: 834-840; doi: 10.1242/dmm.011155
Blumer, Michael J. F.
- Research ArticleSepsis otopathy: experimental sepsis leads to significant hearing impairment due to apoptosis and glutamate excitotoxicity in murine cochleaJoachim Schmutzhard, Rudolf Glueckert, Christian Pritz, Michael J. F. Blumer, Mario Bitsche, Peter Lackner, Manfred Fille, Herbert Riechelmann, Matthias Harkamp, Thongrong Sitthisak, Annelies Schrott-FischerDisease Models & Mechanisms 2013 6: 745-754; doi: 10.1242/dmm.011205
Bockenhauer, Detlef
- Research ArticleGeneration and validation of a zebrafish model of EAST (epilepsy, ataxia, sensorineural deafness and tubulopathy) syndromeFahad Mahmood, Monika Mozere, Anselm A. Zdebik, Horia C. Stanescu, Jonathan Tobin, Philip L. Beales, Robert Kleta, Detlef Bockenhauer, Claire RussellDisease Models & Mechanisms 2013 6: 652-660; doi: 10.1242/dmm.009480
Boehringer, Ashley V.
- Research ArticleMotor neurons and glia exhibit specific individualized responses to TDP-43 expression in a Drosophila model of amyotrophic lateral sclerosisPatricia S. Estes, Scott G. Daniel, Abigail P. Mccallum, Ashley V. Boehringer, Alona S. Sukhina, Rebecca A. Zwick, Daniela C. ZarnescuDisease Models & Mechanisms 2013 6: 721-733; doi: 10.1242/dmm.010710
Bogdanik, Laurent P.
- Research ArticleLoss of the E3 ubiquitin ligase LRSAM1 sensitizes peripheral axons to degeneration in a mouse model of Charcot-Marie-Tooth diseaseLaurent P. Bogdanik, James N. Sleigh, Cong Tian, Mark E. Samuels, Karen Bedard, Kevin L. Seburn, Robert W. BurgessDisease Models & Mechanisms 2013 6: 780-792; doi: 10.1242/dmm.010942
Brumby, Anthony M.
- Research ArticleIn Drosophila, RhoGEF2 cooperates with activated Ras in tumorigenesis through a pathway involving Rho1–Rok–Myosin-II and JNK signallingPeytee Khoo, Kirsten Allan, Lee Willoughby, Anthony M. Brumby, Helena E. RichardsonDisease Models & Mechanisms 2013 6: 661-678; doi: 10.1242/dmm.010066
Burgess, Robert W.
- Research ArticleLoss of the E3 ubiquitin ligase LRSAM1 sensitizes peripheral axons to degeneration in a mouse model of Charcot-Marie-Tooth diseaseLaurent P. Bogdanik, James N. Sleigh, Cong Tian, Mark E. Samuels, Karen Bedard, Kevin L. Seburn, Robert W. BurgessDisease Models & Mechanisms 2013 6: 780-792; doi: 10.1242/dmm.010942
C
Cagan, Ross L.
- EditorialBridging the gap between basic and applied biology: towards preclinical translationRoss L. Cagan, Monica J. Justice, George F. TidmarshDisease Models & Mechanisms 2013 6: 559-561; doi: 10.1242/dmm.012450
Carby, Martin
- Research ArticleA new and clinically relevant murine model of solid-organ transplant aspergillosisSusanne Herbst, Anand Shah, Martin Carby, Gary Chusney, Naresh Kikkeri, Anthony Dorling, Elaine Bignell, Sunil Shaunak, Darius Armstrong-JamesDisease Models & Mechanisms 2013 6: 643-651; doi: 10.1242/dmm.010330
Chernet, Brook T.
- Research ArticleTransmembrane voltage potential is an essential cellular parameter for the detection and control of tumor development in a Xenopus modelBrook T. Chernet, Michael LevinDisease Models & Mechanisms 2013 6: 595-607; doi: 10.1242/dmm.010835
Chhun, Danny C.
- Research ArticleOlfactomedin-1 activity identifies a cell invasion checkpoint during epithelial-mesenchymal transition in the chick embryonic heartAlejandro Lencinas, Danny C. Chhun, Kelvin P. Dan, Kristen D. Ross, Elizabeth A. Hoover, Parker B. Antin, Raymond B. RunyanDisease Models & Mechanisms 2013 6: 632-642; doi: 10.1242/dmm.010595
Chintawar, Satyan
- Research ArticleNeurons and cardiomyocytes derived from induced pluripotent stem cells as a model for mitochondrial defects in Friedreich’s ataxiaAurore Hick, Marie Wattenhofer-Donzé, Satyan Chintawar, Philippe Tropel, Jodie P. Simard, Nadège Vaucamps, David Gall, Laurie Lambot, Cécile André, Laurence Reutenauer, Myriam Rai, Marius Teletin, Nadia Messaddeq, Serge N. Schiffmann, Stéphane Viville, Christopher E. Pearson, Massimo Pandolfo, Hélène PuccioDisease Models & Mechanisms 2013 6: 608-621; doi: 10.1242/dmm.010900
Chusney, Gary
- Research ArticleA new and clinically relevant murine model of solid-organ transplant aspergillosisSusanne Herbst, Anand Shah, Martin Carby, Gary Chusney, Naresh Kikkeri, Anthony Dorling, Elaine Bignell, Sunil Shaunak, Darius Armstrong-JamesDisease Models & Mechanisms 2013 6: 643-651; doi: 10.1242/dmm.010330
Collino, Massimo
- Research ArticlePharmacological preconditioning with erythropoietin attenuates the organ injury and dysfunction induced in a rat model of hemorrhagic shockKiran K. Nandra, Massimo Collino, Mara Rogazzo, Roberto Fantozzi, Nimesh S. A. Patel, Christoph ThiemermannDisease Models & Mechanisms 2013 6: 701-709; doi: 10.1242/dmm.011353
Copp, Andrew J.
- EditorialDeciphering the Mechanisms of Developmental Disorders (DMDD): a new programme for phenotyping embryonic lethal miceTimothy Mohun, David J. Adams, Richard Baldock, Shoumo Bhattacharya, Andrew J. Copp, Myriam Hemberger, Corinne Houart, Matt E. Hurles, Elizabeth Robertson, James C. Smith, Tom Weaver, Wolfgang WeningerDisease Models & Mechanisms 2013 6: 562-566; doi: 10.1242/dmm.011957
- Special ArticleBloomsbury report on mouse embryo phenotyping: recommendations from the IMPC workshop on embryonic lethal screeningDavid Adams, Richard Baldock, Shoumo Bhattacharya, Andrew J. Copp, Mary Dickinson, Nicholas D. E. Greene, Mark Henkelman, Monica Justice, Timothy Mohun, Stephen A. Murray, Erwin Pauws, Michael Raess, Janet Rossant, Tom Weaver, David WestDisease Models & Mechanisms 2013 6: 571-579; doi: 10.1242/dmm.011833
D
Dan, Kelvin P.
- Research ArticleOlfactomedin-1 activity identifies a cell invasion checkpoint during epithelial-mesenchymal transition in the chick embryonic heartAlejandro Lencinas, Danny C. Chhun, Kelvin P. Dan, Kristen D. Ross, Elizabeth A. Hoover, Parker B. Antin, Raymond B. RunyanDisease Models & Mechanisms 2013 6: 632-642; doi: 10.1242/dmm.010595
Daniel, Scott G.
- Research ArticleMotor neurons and glia exhibit specific individualized responses to TDP-43 expression in a Drosophila model of amyotrophic lateral sclerosisPatricia S. Estes, Scott G. Daniel, Abigail P. Mccallum, Ashley V. Boehringer, Alona S. Sukhina, Rebecca A. Zwick, Daniela C. ZarnescuDisease Models & Mechanisms 2013 6: 721-733; doi: 10.1242/dmm.010710
DeVoss, Jason
- Resource ArticleAn entirely automated method to score DSS-induced colitis in mice by digital image analysis of pathology slidesCleopatra Kozlowski, Surinder Jeet, Joseph Beyer, Steve Guerrero, Justin Lesch, Xiaoting Wang, Jason DeVoss, Lauri DiehlDisease Models & Mechanisms 2013 6: 855-865; doi: 10.1242/dmm.011759
Dickinson, Mary
- Special ArticleBloomsbury report on mouse embryo phenotyping: recommendations from the IMPC workshop on embryonic lethal screeningDavid Adams, Richard Baldock, Shoumo Bhattacharya, Andrew J. Copp, Mary Dickinson, Nicholas D. E. Greene, Mark Henkelman, Monica Justice, Timothy Mohun, Stephen A. Murray, Erwin Pauws, Michael Raess, Janet Rossant, Tom Weaver, David WestDisease Models & Mechanisms 2013 6: 571-579; doi: 10.1242/dmm.011833
Diehl, Lauri
- Resource ArticleAn entirely automated method to score DSS-induced colitis in mice by digital image analysis of pathology slidesCleopatra Kozlowski, Surinder Jeet, Joseph Beyer, Steve Guerrero, Justin Lesch, Xiaoting Wang, Jason DeVoss, Lauri DiehlDisease Models & Mechanisms 2013 6: 855-865; doi: 10.1242/dmm.011759
Dolcet, Xavier
- Research ArticleAn inducible knockout mouse to model the cell-autonomous role of PTEN in initiating endometrial, prostate and thyroid neoplasiasCristina Mirantes, Núria Eritja, Maria Alba Dosil, Maria Santacana, Judit Pallares, Sónia Gatius, Laura Bergadà, Oscar Maiques, Xavier Matias-Guiu, Xavier DolcetDisease Models & Mechanisms 2013 6: 710-720; doi: 10.1242/dmm.011445
Dorling, Anthony
- Research ArticleA new and clinically relevant murine model of solid-organ transplant aspergillosisSusanne Herbst, Anand Shah, Martin Carby, Gary Chusney, Naresh Kikkeri, Anthony Dorling, Elaine Bignell, Sunil Shaunak, Darius Armstrong-JamesDisease Models & Mechanisms 2013 6: 643-651; doi: 10.1242/dmm.010330
Dosil, Maria Alba
- Research ArticleAn inducible knockout mouse to model the cell-autonomous role of PTEN in initiating endometrial, prostate and thyroid neoplasiasCristina Mirantes, Núria Eritja, Maria Alba Dosil, Maria Santacana, Judit Pallares, Sónia Gatius, Laura Bergadà, Oscar Maiques, Xavier Matias-Guiu, Xavier DolcetDisease Models & Mechanisms 2013 6: 710-720; doi: 10.1242/dmm.011445
E
Egeblad, Mikala
- ReviewCaught in the act: revealing the metastatic process by live imagingMiriam R. Fein, Mikala EgebladDisease Models & Mechanisms 2013 6: 580-593; doi: 10.1242/dmm.009282
Eritja, Núria
- Research ArticleAn inducible knockout mouse to model the cell-autonomous role of PTEN in initiating endometrial, prostate and thyroid neoplasiasCristina Mirantes, Núria Eritja, Maria Alba Dosil, Maria Santacana, Judit Pallares, Sónia Gatius, Laura Bergadà, Oscar Maiques, Xavier Matias-Guiu, Xavier DolcetDisease Models & Mechanisms 2013 6: 710-720; doi: 10.1242/dmm.011445
Estes, Patricia S.
- Research ArticleMotor neurons and glia exhibit specific individualized responses to TDP-43 expression in a Drosophila model of amyotrophic lateral sclerosisPatricia S. Estes, Scott G. Daniel, Abigail P. Mccallum, Ashley V. Boehringer, Alona S. Sukhina, Rebecca A. Zwick, Daniela C. ZarnescuDisease Models & Mechanisms 2013 6: 721-733; doi: 10.1242/dmm.010710
F
Fantozzi, Roberto
- Research ArticlePharmacological preconditioning with erythropoietin attenuates the organ injury and dysfunction induced in a rat model of hemorrhagic shockKiran K. Nandra, Massimo Collino, Mara Rogazzo, Roberto Fantozzi, Nimesh S. A. Patel, Christoph ThiemermannDisease Models & Mechanisms 2013 6: 701-709; doi: 10.1242/dmm.011353
Fein, Miriam R.
- ReviewCaught in the act: revealing the metastatic process by live imagingMiriam R. Fein, Mikala EgebladDisease Models & Mechanisms 2013 6: 580-593; doi: 10.1242/dmm.009282
Fille, Manfred
- Research ArticleSepsis otopathy: experimental sepsis leads to significant hearing impairment due to apoptosis and glutamate excitotoxicity in murine cochleaJoachim Schmutzhard, Rudolf Glueckert, Christian Pritz, Michael J. F. Blumer, Mario Bitsche, Peter Lackner, Manfred Fille, Herbert Riechelmann, Matthias Harkamp, Thongrong Sitthisak, Annelies Schrott-FischerDisease Models & Mechanisms 2013 6: 745-754; doi: 10.1242/dmm.011205
Forde, Toni S.
- Research ArticleOsteoarticular tissue infection and development of skeletal pathology in murine brucellosisDiogo M. Magnani, Elizabeth T. Lyons, Toni S. Forde, Mohammed T. Shekhani, Vyacheslav A. Adarichev, Gary A. SplitterDisease Models & Mechanisms 2013 6: 811-818; doi: 10.1242/dmm.011056
Fumagalli, Arianna
- Research ArticleElevated expression of the V-ATPase C subunit triggers JNK-dependent cell invasion and overgrowth in a Drosophila epitheliumAstrid G. Petzoldt, Eva Maria Gleixner, Arianna Fumagalli, Thomas Vaccari, Matias SimonsDisease Models & Mechanisms 2013 6: 689-700; doi: 10.1242/dmm.010660
G
Gall, David
- Research ArticleNeurons and cardiomyocytes derived from induced pluripotent stem cells as a model for mitochondrial defects in Friedreich’s ataxiaAurore Hick, Marie Wattenhofer-Donzé, Satyan Chintawar, Philippe Tropel, Jodie P. Simard, Nadège Vaucamps, David Gall, Laurie Lambot, Cécile André, Laurence Reutenauer, Myriam Rai, Marius Teletin, Nadia Messaddeq, Serge N. Schiffmann, Stéphane Viville, Christopher E. Pearson, Massimo Pandolfo, Hélène PuccioDisease Models & Mechanisms 2013 6: 608-621; doi: 10.1242/dmm.010900
Gatius, Sónia
- Research ArticleAn inducible knockout mouse to model the cell-autonomous role of PTEN in initiating endometrial, prostate and thyroid neoplasiasCristina Mirantes, Núria Eritja, Maria Alba Dosil, Maria Santacana, Judit Pallares, Sónia Gatius, Laura Bergadà, Oscar Maiques, Xavier Matias-Guiu, Xavier DolcetDisease Models & Mechanisms 2013 6: 710-720; doi: 10.1242/dmm.011445
Gleixner, Eva Maria
- Research ArticleElevated expression of the V-ATPase C subunit triggers JNK-dependent cell invasion and overgrowth in a Drosophila epitheliumAstrid G. Petzoldt, Eva Maria Gleixner, Arianna Fumagalli, Thomas Vaccari, Matias SimonsDisease Models & Mechanisms 2013 6: 689-700; doi: 10.1242/dmm.010660
Glueckert, Rudolf
- Research ArticleSepsis otopathy: experimental sepsis leads to significant hearing impairment due to apoptosis and glutamate excitotoxicity in murine cochleaJoachim Schmutzhard, Rudolf Glueckert, Christian Pritz, Michael J. F. Blumer, Mario Bitsche, Peter Lackner, Manfred Fille, Herbert Riechelmann, Matthias Harkamp, Thongrong Sitthisak, Annelies Schrott-FischerDisease Models & Mechanisms 2013 6: 745-754; doi: 10.1242/dmm.011205
Gourdon, Geneviève
- Research ArticleFunctional and histopathological identification of the respiratory failure in a DMSXL transgenic mouse model of myotonic dystrophyPetrica-Adrian Panaite, Thierry Kuntzer, Geneviève Gourdon, Johannes Alexander Lobrinus, Ibtissam Barakat-WalterDisease Models & Mechanisms 2013 6: 622-631; doi: 10.1242/dmm.010512
Greene, Nicholas D. E.
- Special ArticleBloomsbury report on mouse embryo phenotyping: recommendations from the IMPC workshop on embryonic lethal screeningDavid Adams, Richard Baldock, Shoumo Bhattacharya, Andrew J. Copp, Mary Dickinson, Nicholas D. E. Greene, Mark Henkelman, Monica Justice, Timothy Mohun, Stephen A. Murray, Erwin Pauws, Michael Raess, Janet Rossant, Tom Weaver, David WestDisease Models & Mechanisms 2013 6: 571-579; doi: 10.1242/dmm.011833
Guerrero, Steve
- Resource ArticleAn entirely automated method to score DSS-induced colitis in mice by digital image analysis of pathology slidesCleopatra Kozlowski, Surinder Jeet, Joseph Beyer, Steve Guerrero, Justin Lesch, Xiaoting Wang, Jason DeVoss, Lauri DiehlDisease Models & Mechanisms 2013 6: 855-865; doi: 10.1242/dmm.011759
Guillemin, Karen
- Research ArticleH. pylori virulence factor CagA increases intestinal cell proliferation by Wnt pathway activation in a transgenic zebrafish modelJames T. Neal, Tracy S. Peterson, Michael L. Kent, Karen GuilleminDisease Models & Mechanisms 2013 6: 802-810; doi: 10.1242/dmm.011163
H
Han, Min
- Research ReportpiggyBac as a high-capacity transgenesis and gene-therapy vector in human cells and miceRongbo Li, Yuan Zhuang, Min Han, Tian Xu, Xiaohui WuDisease Models & Mechanisms 2013 6: 828-833; doi: 10.1242/dmm.010827
Harkamp, Matthias
- Research ArticleSepsis otopathy: experimental sepsis leads to significant hearing impairment due to apoptosis and glutamate excitotoxicity in murine cochleaJoachim Schmutzhard, Rudolf Glueckert, Christian Pritz, Michael J. F. Blumer, Mario Bitsche, Peter Lackner, Manfred Fille, Herbert Riechelmann, Matthias Harkamp, Thongrong Sitthisak, Annelies Schrott-FischerDisease Models & Mechanisms 2013 6: 745-754; doi: 10.1242/dmm.011205
Hasan, Gaiti
- Research ArticleAltered lipid homeostasis in Drosophila InsP3 receptor mutants leads to obesity and hyperphagiaManivannan Subramanian, Suman Kumar Metya, Sufia Sadaf, Satish Kumar, Dominik Schwudke, Gaiti HasanDisease Models & Mechanisms 2013 6: 734-744; doi: 10.1242/dmm.010017
Havrda, Matthew C.
- Research ReportBehavioral abnormalities and Parkinson’s-like histological changes resulting from Id2 inactivation in miceMatthew C. Havrda, Brenton R. Paolella, Nora M. Ward, Kathryn B. HolroydDisease Models & Mechanisms 2013 6: 819-827; doi: 10.1242/dmm.010041
Hemberger, Myriam
- EditorialDeciphering the Mechanisms of Developmental Disorders (DMDD): a new programme for phenotyping embryonic lethal miceTimothy Mohun, David J. Adams, Richard Baldock, Shoumo Bhattacharya, Andrew J. Copp, Myriam Hemberger, Corinne Houart, Matt E. Hurles, Elizabeth Robertson, James C. Smith, Tom Weaver, Wolfgang WeningerDisease Models & Mechanisms 2013 6: 562-566; doi: 10.1242/dmm.011957
Henkelman, Mark
- Special ArticleBloomsbury report on mouse embryo phenotyping: recommendations from the IMPC workshop on embryonic lethal screeningDavid Adams, Richard Baldock, Shoumo Bhattacharya, Andrew J. Copp, Mary Dickinson, Nicholas D. E. Greene, Mark Henkelman, Monica Justice, Timothy Mohun, Stephen A. Murray, Erwin Pauws, Michael Raess, Janet Rossant, Tom Weaver, David WestDisease Models & Mechanisms 2013 6: 571-579; doi: 10.1242/dmm.011833
Herbst, Susanne
- Research ArticleA new and clinically relevant murine model of solid-organ transplant aspergillosisSusanne Herbst, Anand Shah, Martin Carby, Gary Chusney, Naresh Kikkeri, Anthony Dorling, Elaine Bignell, Sunil Shaunak, Darius Armstrong-JamesDisease Models & Mechanisms 2013 6: 643-651; doi: 10.1242/dmm.010330
Hick, Aurore
- Research ArticleNeurons and cardiomyocytes derived from induced pluripotent stem cells as a model for mitochondrial defects in Friedreich’s ataxiaAurore Hick, Marie Wattenhofer-Donzé, Satyan Chintawar, Philippe Tropel, Jodie P. Simard, Nadège Vaucamps, David Gall, Laurie Lambot, Cécile André, Laurence Reutenauer, Myriam Rai, Marius Teletin, Nadia Messaddeq, Serge N. Schiffmann, Stéphane Viville, Christopher E. Pearson, Massimo Pandolfo, Hélène PuccioDisease Models & Mechanisms 2013 6: 608-621; doi: 10.1242/dmm.010900
Holmes, Greg
- Research ArticleFrom shape to cells: mouse models reveal mechanisms altering palate development in Apert syndromeNeus Martínez-Abadías, Greg Holmes, Talia Pankratz, Yingli Wang, Xueyan Zhou, Ethylin Wang Jabs, Joan T. RichtsmeierDisease Models & Mechanisms 2013 6: 768-779; doi: 10.1242/dmm.010397
Holroyd, Kathryn B.
- Research ReportBehavioral abnormalities and Parkinson’s-like histological changes resulting from Id2 inactivation in miceMatthew C. Havrda, Brenton R. Paolella, Nora M. Ward, Kathryn B. HolroydDisease Models & Mechanisms 2013 6: 819-827; doi: 10.1242/dmm.010041
Hoover, Elizabeth A.
- Research ArticleOlfactomedin-1 activity identifies a cell invasion checkpoint during epithelial-mesenchymal transition in the chick embryonic heartAlejandro Lencinas, Danny C. Chhun, Kelvin P. Dan, Kristen D. Ross, Elizabeth A. Hoover, Parker B. Antin, Raymond B. RunyanDisease Models & Mechanisms 2013 6: 632-642; doi: 10.1242/dmm.010595
Houart, Corinne
- EditorialDeciphering the Mechanisms of Developmental Disorders (DMDD): a new programme for phenotyping embryonic lethal miceTimothy Mohun, David J. Adams, Richard Baldock, Shoumo Bhattacharya, Andrew J. Copp, Myriam Hemberger, Corinne Houart, Matt E. Hurles, Elizabeth Robertson, James C. Smith, Tom Weaver, Wolfgang WeningerDisease Models & Mechanisms 2013 6: 562-566; doi: 10.1242/dmm.011957
Hurles, Matt E.
- EditorialDeciphering the Mechanisms of Developmental Disorders (DMDD): a new programme for phenotyping embryonic lethal miceTimothy Mohun, David J. Adams, Richard Baldock, Shoumo Bhattacharya, Andrew J. Copp, Myriam Hemberger, Corinne Houart, Matt E. Hurles, Elizabeth Robertson, James C. Smith, Tom Weaver, Wolfgang WeningerDisease Models & Mechanisms 2013 6: 562-566; doi: 10.1242/dmm.011957
I
Iwamoto, Hiroyuki
- Research ReportThe fraction of strongly bound cross-bridges is increased in mice that carry the myopathy-linked myosin heavy chain mutation MYH4L342QJohan Lindqvist, Hiroyuki Iwamoto, Gonzalo Blanco, Julien OchalaDisease Models & Mechanisms 2013 6: 834-840; doi: 10.1242/dmm.011155
J
Jabs, Ethylin Wang
- Research ArticleFrom shape to cells: mouse models reveal mechanisms altering palate development in Apert syndromeNeus Martínez-Abadías, Greg Holmes, Talia Pankratz, Yingli Wang, Xueyan Zhou, Ethylin Wang Jabs, Joan T. RichtsmeierDisease Models & Mechanisms 2013 6: 768-779; doi: 10.1242/dmm.010397
Jeet, Surinder
- Resource ArticleAn entirely automated method to score DSS-induced colitis in mice by digital image analysis of pathology slidesCleopatra Kozlowski, Surinder Jeet, Joseph Beyer, Steve Guerrero, Justin Lesch, Xiaoting Wang, Jason DeVoss, Lauri DiehlDisease Models & Mechanisms 2013 6: 855-865; doi: 10.1242/dmm.011759
Justice, Monica
- Special ArticleBloomsbury report on mouse embryo phenotyping: recommendations from the IMPC workshop on embryonic lethal screeningDavid Adams, Richard Baldock, Shoumo Bhattacharya, Andrew J. Copp, Mary Dickinson, Nicholas D. E. Greene, Mark Henkelman, Monica Justice, Timothy Mohun, Stephen A. Murray, Erwin Pauws, Michael Raess, Janet Rossant, Tom Weaver, David WestDisease Models & Mechanisms 2013 6: 571-579; doi: 10.1242/dmm.011833
Justice, Monica J.
- EditorialBridging the gap between basic and applied biology: towards preclinical translationRoss L. Cagan, Monica J. Justice, George F. TidmarshDisease Models & Mechanisms 2013 6: 559-561; doi: 10.1242/dmm.012450
K
Kent, Michael L.
- Research ArticleH. pylori virulence factor CagA increases intestinal cell proliferation by Wnt pathway activation in a transgenic zebrafish modelJames T. Neal, Tracy S. Peterson, Michael L. Kent, Karen GuilleminDisease Models & Mechanisms 2013 6: 802-810; doi: 10.1242/dmm.011163
Khoo, Peytee
- Research ArticleIn Drosophila, RhoGEF2 cooperates with activated Ras in tumorigenesis through a pathway involving Rho1–Rok–Myosin-II and JNK signallingPeytee Khoo, Kirsten Allan, Lee Willoughby, Anthony M. Brumby, Helena E. RichardsonDisease Models & Mechanisms 2013 6: 661-678; doi: 10.1242/dmm.010066
Kikkeri, Naresh
- Research ArticleA new and clinically relevant murine model of solid-organ transplant aspergillosisSusanne Herbst, Anand Shah, Martin Carby, Gary Chusney, Naresh Kikkeri, Anthony Dorling, Elaine Bignell, Sunil Shaunak, Darius Armstrong-JamesDisease Models & Mechanisms 2013 6: 643-651; doi: 10.1242/dmm.010330
Kleta, Robert
- Research ArticleGeneration and validation of a zebrafish model of EAST (epilepsy, ataxia, sensorineural deafness and tubulopathy) syndromeFahad Mahmood, Monika Mozere, Anselm A. Zdebik, Horia C. Stanescu, Jonathan Tobin, Philip L. Beales, Robert Kleta, Detlef Bockenhauer, Claire RussellDisease Models & Mechanisms 2013 6: 652-660; doi: 10.1242/dmm.009480
Kozlowski, Cleopatra
- Resource ArticleAn entirely automated method to score DSS-induced colitis in mice by digital image analysis of pathology slidesCleopatra Kozlowski, Surinder Jeet, Joseph Beyer, Steve Guerrero, Justin Lesch, Xiaoting Wang, Jason DeVoss, Lauri DiehlDisease Models & Mechanisms 2013 6: 855-865; doi: 10.1242/dmm.011759
Kumar, Satish
- Research ArticleAltered lipid homeostasis in Drosophila InsP3 receptor mutants leads to obesity and hyperphagiaManivannan Subramanian, Suman Kumar Metya, Sufia Sadaf, Satish Kumar, Dominik Schwudke, Gaiti HasanDisease Models & Mechanisms 2013 6: 734-744; doi: 10.1242/dmm.010017
Kuntzer, Thierry
- Research ArticleFunctional and histopathological identification of the respiratory failure in a DMSXL transgenic mouse model of myotonic dystrophyPetrica-Adrian Panaite, Thierry Kuntzer, Geneviève Gourdon, Johannes Alexander Lobrinus, Ibtissam Barakat-WalterDisease Models & Mechanisms 2013 6: 622-631; doi: 10.1242/dmm.010512
Kuraitis, Drew
- Research ArticleA necrotic stimulus is required to maximize matrix-mediated myogenesis in miceDrew Kuraitis, Maria Grazia Berardinelli, Erik J. Suuronen, Antonio MusaròDisease Models & Mechanisms 2013 6: 793-801; doi: 10.1242/dmm.011072
L
Lackner, Peter
- Research ArticleSepsis otopathy: experimental sepsis leads to significant hearing impairment due to apoptosis and glutamate excitotoxicity in murine cochleaJoachim Schmutzhard, Rudolf Glueckert, Christian Pritz, Michael J. F. Blumer, Mario Bitsche, Peter Lackner, Manfred Fille, Herbert Riechelmann, Matthias Harkamp, Thongrong Sitthisak, Annelies Schrott-FischerDisease Models & Mechanisms 2013 6: 745-754; doi: 10.1242/dmm.011205
Lambot, Laurie
- Research ArticleNeurons and cardiomyocytes derived from induced pluripotent stem cells as a model for mitochondrial defects in Friedreich’s ataxiaAurore Hick, Marie Wattenhofer-Donzé, Satyan Chintawar, Philippe Tropel, Jodie P. Simard, Nadège Vaucamps, David Gall, Laurie Lambot, Cécile André, Laurence Reutenauer, Myriam Rai, Marius Teletin, Nadia Messaddeq, Serge N. Schiffmann, Stéphane Viville, Christopher E. Pearson, Massimo Pandolfo, Hélène PuccioDisease Models & Mechanisms 2013 6: 608-621; doi: 10.1242/dmm.010900
Lencinas, Alejandro
- Research ArticleOlfactomedin-1 activity identifies a cell invasion checkpoint during epithelial-mesenchymal transition in the chick embryonic heartAlejandro Lencinas, Danny C. Chhun, Kelvin P. Dan, Kristen D. Ross, Elizabeth A. Hoover, Parker B. Antin, Raymond B. RunyanDisease Models & Mechanisms 2013 6: 632-642; doi: 10.1242/dmm.010595
Lesch, Justin
- Resource ArticleAn entirely automated method to score DSS-induced colitis in mice by digital image analysis of pathology slidesCleopatra Kozlowski, Surinder Jeet, Joseph Beyer, Steve Guerrero, Justin Lesch, Xiaoting Wang, Jason DeVoss, Lauri DiehlDisease Models & Mechanisms 2013 6: 855-865; doi: 10.1242/dmm.011759
Levin, Michael
- Research ArticleTransmembrane voltage potential is an essential cellular parameter for the detection and control of tumor development in a Xenopus modelBrook T. Chernet, Michael LevinDisease Models & Mechanisms 2013 6: 595-607; doi: 10.1242/dmm.010835
Li, Rongbo
- Research ReportpiggyBac as a high-capacity transgenesis and gene-therapy vector in human cells and miceRongbo Li, Yuan Zhuang, Min Han, Tian Xu, Xiaohui WuDisease Models & Mechanisms 2013 6: 828-833; doi: 10.1242/dmm.010827
Lindqvist, Johan
- Research ReportThe fraction of strongly bound cross-bridges is increased in mice that carry the myopathy-linked myosin heavy chain mutation MYH4L342QJohan Lindqvist, Hiroyuki Iwamoto, Gonzalo Blanco, Julien OchalaDisease Models & Mechanisms 2013 6: 834-840; doi: 10.1242/dmm.011155
Lobrinus, Johannes Alexander
- Research ArticleFunctional and histopathological identification of the respiratory failure in a DMSXL transgenic mouse model of myotonic dystrophyPetrica-Adrian Panaite, Thierry Kuntzer, Geneviève Gourdon, Johannes Alexander Lobrinus, Ibtissam Barakat-WalterDisease Models & Mechanisms 2013 6: 622-631; doi: 10.1242/dmm.010512
Lyons, Elizabeth T.
- Research ArticleOsteoarticular tissue infection and development of skeletal pathology in murine brucellosisDiogo M. Magnani, Elizabeth T. Lyons, Toni S. Forde, Mohammed T. Shekhani, Vyacheslav A. Adarichev, Gary A. SplitterDisease Models & Mechanisms 2013 6: 811-818; doi: 10.1242/dmm.011056
M
Magnani, Diogo M.
- Research ArticleOsteoarticular tissue infection and development of skeletal pathology in murine brucellosisDiogo M. Magnani, Elizabeth T. Lyons, Toni S. Forde, Mohammed T. Shekhani, Vyacheslav A. Adarichev, Gary A. SplitterDisease Models & Mechanisms 2013 6: 811-818; doi: 10.1242/dmm.011056
Mahmood, Fahad
- Research ArticleGeneration and validation of a zebrafish model of EAST (epilepsy, ataxia, sensorineural deafness and tubulopathy) syndromeFahad Mahmood, Monika Mozere, Anselm A. Zdebik, Horia C. Stanescu, Jonathan Tobin, Philip L. Beales, Robert Kleta, Detlef Bockenhauer, Claire RussellDisease Models & Mechanisms 2013 6: 652-660; doi: 10.1242/dmm.009480
Maiques, Oscar
- Research ArticleAn inducible knockout mouse to model the cell-autonomous role of PTEN in initiating endometrial, prostate and thyroid neoplasiasCristina Mirantes, Núria Eritja, Maria Alba Dosil, Maria Santacana, Judit Pallares, Sónia Gatius, Laura Bergadà, Oscar Maiques, Xavier Matias-Guiu, Xavier DolcetDisease Models & Mechanisms 2013 6: 710-720; doi: 10.1242/dmm.011445
Martínez-Abadías, Neus
- Research ArticleFrom shape to cells: mouse models reveal mechanisms altering palate development in Apert syndromeNeus Martínez-Abadías, Greg Holmes, Talia Pankratz, Yingli Wang, Xueyan Zhou, Ethylin Wang Jabs, Joan T. RichtsmeierDisease Models & Mechanisms 2013 6: 768-779; doi: 10.1242/dmm.010397
Matias-Guiu, Xavier
- Research ArticleAn inducible knockout mouse to model the cell-autonomous role of PTEN in initiating endometrial, prostate and thyroid neoplasiasCristina Mirantes, Núria Eritja, Maria Alba Dosil, Maria Santacana, Judit Pallares, Sónia Gatius, Laura Bergadà, Oscar Maiques, Xavier Matias-Guiu, Xavier DolcetDisease Models & Mechanisms 2013 6: 710-720; doi: 10.1242/dmm.011445
Mccallum, Abigail P.
- Research ArticleMotor neurons and glia exhibit specific individualized responses to TDP-43 expression in a Drosophila model of amyotrophic lateral sclerosisPatricia S. Estes, Scott G. Daniel, Abigail P. Mccallum, Ashley V. Boehringer, Alona S. Sukhina, Rebecca A. Zwick, Daniela C. ZarnescuDisease Models & Mechanisms 2013 6: 721-733; doi: 10.1242/dmm.010710
Mei, Xue
- Research ArticleMechanisms of prickle1a function in zebrafish epilepsy and retinal neurogenesisXue Mei, Shu Wu, Alexander G. Bassuk, Diane C. SlusarskiDisease Models & Mechanisms 2013 6: 679-688; doi: 10.1242/dmm.010793
Meijer, Annemarie H.
- Resource ArticleFunctional analysis of a zebrafish myd88 mutant identifies key transcriptional components of the innate immune systemMichiel van der Vaart, Joost J. van Soest, Herman P. Spaink, Annemarie H. MeijerDisease Models & Mechanisms 2013 6: 841-854; doi: 10.1242/dmm.010843
Messaddeq, Nadia
- Research ArticleNeurons and cardiomyocytes derived from induced pluripotent stem cells as a model for mitochondrial defects in Friedreich’s ataxiaAurore Hick, Marie Wattenhofer-Donzé, Satyan Chintawar, Philippe Tropel, Jodie P. Simard, Nadège Vaucamps, David Gall, Laurie Lambot, Cécile André, Laurence Reutenauer, Myriam Rai, Marius Teletin, Nadia Messaddeq, Serge N. Schiffmann, Stéphane Viville, Christopher E. Pearson, Massimo Pandolfo, Hélène PuccioDisease Models & Mechanisms 2013 6: 608-621; doi: 10.1242/dmm.010900
Metya, Suman Kumar
- Research ArticleAltered lipid homeostasis in Drosophila InsP3 receptor mutants leads to obesity and hyperphagiaManivannan Subramanian, Suman Kumar Metya, Sufia Sadaf, Satish Kumar, Dominik Schwudke, Gaiti HasanDisease Models & Mechanisms 2013 6: 734-744; doi: 10.1242/dmm.010017
Mirantes, Cristina
- Research ArticleAn inducible knockout mouse to model the cell-autonomous role of PTEN in initiating endometrial, prostate and thyroid neoplasiasCristina Mirantes, Núria Eritja, Maria Alba Dosil, Maria Santacana, Judit Pallares, Sónia Gatius, Laura Bergadà, Oscar Maiques, Xavier Matias-Guiu, Xavier DolcetDisease Models & Mechanisms 2013 6: 710-720; doi: 10.1242/dmm.011445
Mohun, Timothy
- EditorialDeciphering the Mechanisms of Developmental Disorders (DMDD): a new programme for phenotyping embryonic lethal miceTimothy Mohun, David J. Adams, Richard Baldock, Shoumo Bhattacharya, Andrew J. Copp, Myriam Hemberger, Corinne Houart, Matt E. Hurles, Elizabeth Robertson, James C. Smith, Tom Weaver, Wolfgang WeningerDisease Models & Mechanisms 2013 6: 562-566; doi: 10.1242/dmm.011957
- Special ArticleBloomsbury report on mouse embryo phenotyping: recommendations from the IMPC workshop on embryonic lethal screeningDavid Adams, Richard Baldock, Shoumo Bhattacharya, Andrew J. Copp, Mary Dickinson, Nicholas D. E. Greene, Mark Henkelman, Monica Justice, Timothy Mohun, Stephen A. Murray, Erwin Pauws, Michael Raess, Janet Rossant, Tom Weaver, David WestDisease Models & Mechanisms 2013 6: 571-579; doi: 10.1242/dmm.011833
Mozere, Monika
- Research ArticleGeneration and validation of a zebrafish model of EAST (epilepsy, ataxia, sensorineural deafness and tubulopathy) syndromeFahad Mahmood, Monika Mozere, Anselm A. Zdebik, Horia C. Stanescu, Jonathan Tobin, Philip L. Beales, Robert Kleta, Detlef Bockenhauer, Claire RussellDisease Models & Mechanisms 2013 6: 652-660; doi: 10.1242/dmm.009480
Murray, Stephen A.
- Special ArticleBloomsbury report on mouse embryo phenotyping: recommendations from the IMPC workshop on embryonic lethal screeningDavid Adams, Richard Baldock, Shoumo Bhattacharya, Andrew J. Copp, Mary Dickinson, Nicholas D. E. Greene, Mark Henkelman, Monica Justice, Timothy Mohun, Stephen A. Murray, Erwin Pauws, Michael Raess, Janet Rossant, Tom Weaver, David WestDisease Models & Mechanisms 2013 6: 571-579; doi: 10.1242/dmm.011833
Musarò, Antonio
- Research ArticleA necrotic stimulus is required to maximize matrix-mediated myogenesis in miceDrew Kuraitis, Maria Grazia Berardinelli, Erik J. Suuronen, Antonio MusaròDisease Models & Mechanisms 2013 6: 793-801; doi: 10.1242/dmm.011072
N
Nandra, Kiran K.
- Research ArticlePharmacological preconditioning with erythropoietin attenuates the organ injury and dysfunction induced in a rat model of hemorrhagic shockKiran K. Nandra, Massimo Collino, Mara Rogazzo, Roberto Fantozzi, Nimesh S. A. Patel, Christoph ThiemermannDisease Models & Mechanisms 2013 6: 701-709; doi: 10.1242/dmm.011353
Neal, James T.
- Research ArticleH. pylori virulence factor CagA increases intestinal cell proliferation by Wnt pathway activation in a transgenic zebrafish modelJames T. Neal, Tracy S. Peterson, Michael L. Kent, Karen GuilleminDisease Models & Mechanisms 2013 6: 802-810; doi: 10.1242/dmm.011163
O
Ochala, Julien
- Research ReportThe fraction of strongly bound cross-bridges is increased in mice that carry the myopathy-linked myosin heavy chain mutation MYH4L342QJohan Lindqvist, Hiroyuki Iwamoto, Gonzalo Blanco, Julien OchalaDisease Models & Mechanisms 2013 6: 834-840; doi: 10.1242/dmm.011155
P
Pallares, Judit
- Research ArticleAn inducible knockout mouse to model the cell-autonomous role of PTEN in initiating endometrial, prostate and thyroid neoplasiasCristina Mirantes, Núria Eritja, Maria Alba Dosil, Maria Santacana, Judit Pallares, Sónia Gatius, Laura Bergadà, Oscar Maiques, Xavier Matias-Guiu, Xavier DolcetDisease Models & Mechanisms 2013 6: 710-720; doi: 10.1242/dmm.011445
Panaite, Petrica-Adrian
- Research ArticleFunctional and histopathological identification of the respiratory failure in a DMSXL transgenic mouse model of myotonic dystrophyPetrica-Adrian Panaite, Thierry Kuntzer, Geneviève Gourdon, Johannes Alexander Lobrinus, Ibtissam Barakat-WalterDisease Models & Mechanisms 2013 6: 622-631; doi: 10.1242/dmm.010512
Pandolfo, Massimo
- Research ArticleNeurons and cardiomyocytes derived from induced pluripotent stem cells as a model for mitochondrial defects in Friedreich’s ataxiaAurore Hick, Marie Wattenhofer-Donzé, Satyan Chintawar, Philippe Tropel, Jodie P. Simard, Nadège Vaucamps, David Gall, Laurie Lambot, Cécile André, Laurence Reutenauer, Myriam Rai, Marius Teletin, Nadia Messaddeq, Serge N. Schiffmann, Stéphane Viville, Christopher E. Pearson, Massimo Pandolfo, Hélène PuccioDisease Models & Mechanisms 2013 6: 608-621; doi: 10.1242/dmm.010900
Pankratz, Talia
- Research ArticleFrom shape to cells: mouse models reveal mechanisms altering palate development in Apert syndromeNeus Martínez-Abadías, Greg Holmes, Talia Pankratz, Yingli Wang, Xueyan Zhou, Ethylin Wang Jabs, Joan T. RichtsmeierDisease Models & Mechanisms 2013 6: 768-779; doi: 10.1242/dmm.010397
Paolella, Brenton R.
- Research ReportBehavioral abnormalities and Parkinson’s-like histological changes resulting from Id2 inactivation in miceMatthew C. Havrda, Brenton R. Paolella, Nora M. Ward, Kathryn B. HolroydDisease Models & Mechanisms 2013 6: 819-827; doi: 10.1242/dmm.010041
Patel, Nimesh S. A.
- Research ArticlePharmacological preconditioning with erythropoietin attenuates the organ injury and dysfunction induced in a rat model of hemorrhagic shockKiran K. Nandra, Massimo Collino, Mara Rogazzo, Roberto Fantozzi, Nimesh S. A. Patel, Christoph ThiemermannDisease Models & Mechanisms 2013 6: 701-709; doi: 10.1242/dmm.011353
Pauws, Erwin
- Special ArticleBloomsbury report on mouse embryo phenotyping: recommendations from the IMPC workshop on embryonic lethal screeningDavid Adams, Richard Baldock, Shoumo Bhattacharya, Andrew J. Copp, Mary Dickinson, Nicholas D. E. Greene, Mark Henkelman, Monica Justice, Timothy Mohun, Stephen A. Murray, Erwin Pauws, Michael Raess, Janet Rossant, Tom Weaver, David WestDisease Models & Mechanisms 2013 6: 571-579; doi: 10.1242/dmm.011833
Pearson, Christopher E.
- Research ArticleNeurons and cardiomyocytes derived from induced pluripotent stem cells as a model for mitochondrial defects in Friedreich’s ataxiaAurore Hick, Marie Wattenhofer-Donzé, Satyan Chintawar, Philippe Tropel, Jodie P. Simard, Nadège Vaucamps, David Gall, Laurie Lambot, Cécile André, Laurence Reutenauer, Myriam Rai, Marius Teletin, Nadia Messaddeq, Serge N. Schiffmann, Stéphane Viville, Christopher E. Pearson, Massimo Pandolfo, Hélène PuccioDisease Models & Mechanisms 2013 6: 608-621; doi: 10.1242/dmm.010900
Peterson, Tracy S.
- Research ArticleH. pylori virulence factor CagA increases intestinal cell proliferation by Wnt pathway activation in a transgenic zebrafish modelJames T. Neal, Tracy S. Peterson, Michael L. Kent, Karen GuilleminDisease Models & Mechanisms 2013 6: 802-810; doi: 10.1242/dmm.011163
Petzoldt, Astrid G.
- Research ArticleElevated expression of the V-ATPase C subunit triggers JNK-dependent cell invasion and overgrowth in a Drosophila epitheliumAstrid G. Petzoldt, Eva Maria Gleixner, Arianna Fumagalli, Thomas Vaccari, Matias SimonsDisease Models & Mechanisms 2013 6: 689-700; doi: 10.1242/dmm.010660
Pritz, Christian
- Research ArticleSepsis otopathy: experimental sepsis leads to significant hearing impairment due to apoptosis and glutamate excitotoxicity in murine cochleaJoachim Schmutzhard, Rudolf Glueckert, Christian Pritz, Michael J. F. Blumer, Mario Bitsche, Peter Lackner, Manfred Fille, Herbert Riechelmann, Matthias Harkamp, Thongrong Sitthisak, Annelies Schrott-FischerDisease Models & Mechanisms 2013 6: 745-754; doi: 10.1242/dmm.011205
Puccio, Hélène
- Research ArticleNeurons and cardiomyocytes derived from induced pluripotent stem cells as a model for mitochondrial defects in Friedreich’s ataxiaAurore Hick, Marie Wattenhofer-Donzé, Satyan Chintawar, Philippe Tropel, Jodie P. Simard, Nadège Vaucamps, David Gall, Laurie Lambot, Cécile André, Laurence Reutenauer, Myriam Rai, Marius Teletin, Nadia Messaddeq, Serge N. Schiffmann, Stéphane Viville, Christopher E. Pearson, Massimo Pandolfo, Hélène PuccioDisease Models & Mechanisms 2013 6: 608-621; doi: 10.1242/dmm.010900
R
Raess, Michael
- Special ArticleBloomsbury report on mouse embryo phenotyping: recommendations from the IMPC workshop on embryonic lethal screeningDavid Adams, Richard Baldock, Shoumo Bhattacharya, Andrew J. Copp, Mary Dickinson, Nicholas D. E. Greene, Mark Henkelman, Monica Justice, Timothy Mohun, Stephen A. Murray, Erwin Pauws, Michael Raess, Janet Rossant, Tom Weaver, David WestDisease Models & Mechanisms 2013 6: 571-579; doi: 10.1242/dmm.011833
Rai, Myriam
- Research ArticleNeurons and cardiomyocytes derived from induced pluripotent stem cells as a model for mitochondrial defects in Friedreich’s ataxiaAurore Hick, Marie Wattenhofer-Donzé, Satyan Chintawar, Philippe Tropel, Jodie P. Simard, Nadège Vaucamps, David Gall, Laurie Lambot, Cécile André, Laurence Reutenauer, Myriam Rai, Marius Teletin, Nadia Messaddeq, Serge N. Schiffmann, Stéphane Viville, Christopher E. Pearson, Massimo Pandolfo, Hélène PuccioDisease Models & Mechanisms 2013 6: 608-621; doi: 10.1242/dmm.010900
Reutenauer, Laurence
- Research ArticleNeurons and cardiomyocytes derived from induced pluripotent stem cells as a model for mitochondrial defects in Friedreich’s ataxiaAurore Hick, Marie Wattenhofer-Donzé, Satyan Chintawar, Philippe Tropel, Jodie P. Simard, Nadège Vaucamps, David Gall, Laurie Lambot, Cécile André, Laurence Reutenauer, Myriam Rai, Marius Teletin, Nadia Messaddeq, Serge N. Schiffmann, Stéphane Viville, Christopher E. Pearson, Massimo Pandolfo, Hélène PuccioDisease Models & Mechanisms 2013 6: 608-621; doi: 10.1242/dmm.010900
Richardson, Helena E.
- Research ArticleIn Drosophila, RhoGEF2 cooperates with activated Ras in tumorigenesis through a pathway involving Rho1–Rok–Myosin-II and JNK signallingPeytee Khoo, Kirsten Allan, Lee Willoughby, Anthony M. Brumby, Helena E. RichardsonDisease Models & Mechanisms 2013 6: 661-678; doi: 10.1242/dmm.010066
Richtsmeier, Joan T.
- Research ArticleFrom shape to cells: mouse models reveal mechanisms altering palate development in Apert syndromeNeus Martínez-Abadías, Greg Holmes, Talia Pankratz, Yingli Wang, Xueyan Zhou, Ethylin Wang Jabs, Joan T. RichtsmeierDisease Models & Mechanisms 2013 6: 768-779; doi: 10.1242/dmm.010397
Riechelmann, Herbert
- Research ArticleSepsis otopathy: experimental sepsis leads to significant hearing impairment due to apoptosis and glutamate excitotoxicity in murine cochleaJoachim Schmutzhard, Rudolf Glueckert, Christian Pritz, Michael J. F. Blumer, Mario Bitsche, Peter Lackner, Manfred Fille, Herbert Riechelmann, Matthias Harkamp, Thongrong Sitthisak, Annelies Schrott-FischerDisease Models & Mechanisms 2013 6: 745-754; doi: 10.1242/dmm.011205
Robertson, Elizabeth
- EditorialDeciphering the Mechanisms of Developmental Disorders (DMDD): a new programme for phenotyping embryonic lethal miceTimothy Mohun, David J. Adams, Richard Baldock, Shoumo Bhattacharya, Andrew J. Copp, Myriam Hemberger, Corinne Houart, Matt E. Hurles, Elizabeth Robertson, James C. Smith, Tom Weaver, Wolfgang WeningerDisease Models & Mechanisms 2013 6: 562-566; doi: 10.1242/dmm.011957
Rogazzo, Mara
- Research ArticlePharmacological preconditioning with erythropoietin attenuates the organ injury and dysfunction induced in a rat model of hemorrhagic shockKiran K. Nandra, Massimo Collino, Mara Rogazzo, Roberto Fantozzi, Nimesh S. A. Patel, Christoph ThiemermannDisease Models & Mechanisms 2013 6: 701-709; doi: 10.1242/dmm.011353
Ross, Kristen D.
- Research ArticleOlfactomedin-1 activity identifies a cell invasion checkpoint during epithelial-mesenchymal transition in the chick embryonic heartAlejandro Lencinas, Danny C. Chhun, Kelvin P. Dan, Kristen D. Ross, Elizabeth A. Hoover, Parker B. Antin, Raymond B. RunyanDisease Models & Mechanisms 2013 6: 632-642; doi: 10.1242/dmm.010595
Rossant, Janet
- Special ArticleBloomsbury report on mouse embryo phenotyping: recommendations from the IMPC workshop on embryonic lethal screeningDavid Adams, Richard Baldock, Shoumo Bhattacharya, Andrew J. Copp, Mary Dickinson, Nicholas D. E. Greene, Mark Henkelman, Monica Justice, Timothy Mohun, Stephen A. Murray, Erwin Pauws, Michael Raess, Janet Rossant, Tom Weaver, David WestDisease Models & Mechanisms 2013 6: 571-579; doi: 10.1242/dmm.011833
Runyan, Raymond B.
- Research ArticleOlfactomedin-1 activity identifies a cell invasion checkpoint during epithelial-mesenchymal transition in the chick embryonic heartAlejandro Lencinas, Danny C. Chhun, Kelvin P. Dan, Kristen D. Ross, Elizabeth A. Hoover, Parker B. Antin, Raymond B. RunyanDisease Models & Mechanisms 2013 6: 632-642; doi: 10.1242/dmm.010595
Russell, Claire
- Research ArticleGeneration and validation of a zebrafish model of EAST (epilepsy, ataxia, sensorineural deafness and tubulopathy) syndromeFahad Mahmood, Monika Mozere, Anselm A. Zdebik, Horia C. Stanescu, Jonathan Tobin, Philip L. Beales, Robert Kleta, Detlef Bockenhauer, Claire RussellDisease Models & Mechanisms 2013 6: 652-660; doi: 10.1242/dmm.009480
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Sadaf, Sufia
- Research ArticleAltered lipid homeostasis in Drosophila InsP3 receptor mutants leads to obesity and hyperphagiaManivannan Subramanian, Suman Kumar Metya, Sufia Sadaf, Satish Kumar, Dominik Schwudke, Gaiti HasanDisease Models & Mechanisms 2013 6: 734-744; doi: 10.1242/dmm.010017
Samuels, Mark E.
- Research ArticleLoss of the E3 ubiquitin ligase LRSAM1 sensitizes peripheral axons to degeneration in a mouse model of Charcot-Marie-Tooth diseaseLaurent P. Bogdanik, James N. Sleigh, Cong Tian, Mark E. Samuels, Karen Bedard, Kevin L. Seburn, Robert W. BurgessDisease Models & Mechanisms 2013 6: 780-792; doi: 10.1242/dmm.010942
Santacana, Maria
- Research ArticleAn inducible knockout mouse to model the cell-autonomous role of PTEN in initiating endometrial, prostate and thyroid neoplasiasCristina Mirantes, Núria Eritja, Maria Alba Dosil, Maria Santacana, Judit Pallares, Sónia Gatius, Laura Bergadà, Oscar Maiques, Xavier Matias-Guiu, Xavier DolcetDisease Models & Mechanisms 2013 6: 710-720; doi: 10.1242/dmm.011445
Schiffmann, Serge N.
- Research ArticleNeurons and cardiomyocytes derived from induced pluripotent stem cells as a model for mitochondrial defects in Friedreich’s ataxiaAurore Hick, Marie Wattenhofer-Donzé, Satyan Chintawar, Philippe Tropel, Jodie P. Simard, Nadège Vaucamps, David Gall, Laurie Lambot, Cécile André, Laurence Reutenauer, Myriam Rai, Marius Teletin, Nadia Messaddeq, Serge N. Schiffmann, Stéphane Viville, Christopher E. Pearson, Massimo Pandolfo, Hélène PuccioDisease Models & Mechanisms 2013 6: 608-621; doi: 10.1242/dmm.010900
Schmutzhard, Joachim
- Research ArticleSepsis otopathy: experimental sepsis leads to significant hearing impairment due to apoptosis and glutamate excitotoxicity in murine cochleaJoachim Schmutzhard, Rudolf Glueckert, Christian Pritz, Michael J. F. Blumer, Mario Bitsche, Peter Lackner, Manfred Fille, Herbert Riechelmann, Matthias Harkamp, Thongrong Sitthisak, Annelies Schrott-FischerDisease Models & Mechanisms 2013 6: 745-754; doi: 10.1242/dmm.011205
Schrott-Fischer, Annelies
- Research ArticleSepsis otopathy: experimental sepsis leads to significant hearing impairment due to apoptosis and glutamate excitotoxicity in murine cochleaJoachim Schmutzhard, Rudolf Glueckert, Christian Pritz, Michael J. F. Blumer, Mario Bitsche, Peter Lackner, Manfred Fille, Herbert Riechelmann, Matthias Harkamp, Thongrong Sitthisak, Annelies Schrott-FischerDisease Models & Mechanisms 2013 6: 745-754; doi: 10.1242/dmm.011205
Schwudke, Dominik
- Research ArticleAltered lipid homeostasis in Drosophila InsP3 receptor mutants leads to obesity and hyperphagiaManivannan Subramanian, Suman Kumar Metya, Sufia Sadaf, Satish Kumar, Dominik Schwudke, Gaiti HasanDisease Models & Mechanisms 2013 6: 734-744; doi: 10.1242/dmm.010017
Seburn, Kevin L.
- Research ArticleLoss of the E3 ubiquitin ligase LRSAM1 sensitizes peripheral axons to degeneration in a mouse model of Charcot-Marie-Tooth diseaseLaurent P. Bogdanik, James N. Sleigh, Cong Tian, Mark E. Samuels, Karen Bedard, Kevin L. Seburn, Robert W. BurgessDisease Models & Mechanisms 2013 6: 780-792; doi: 10.1242/dmm.010942
Shah, Anand
- Research ArticleA new and clinically relevant murine model of solid-organ transplant aspergillosisSusanne Herbst, Anand Shah, Martin Carby, Gary Chusney, Naresh Kikkeri, Anthony Dorling, Elaine Bignell, Sunil Shaunak, Darius Armstrong-JamesDisease Models & Mechanisms 2013 6: 643-651; doi: 10.1242/dmm.010330
Shaunak, Sunil
- Research ArticleA new and clinically relevant murine model of solid-organ transplant aspergillosisSusanne Herbst, Anand Shah, Martin Carby, Gary Chusney, Naresh Kikkeri, Anthony Dorling, Elaine Bignell, Sunil Shaunak, Darius Armstrong-JamesDisease Models & Mechanisms 2013 6: 643-651; doi: 10.1242/dmm.010330
Shekhani, Mohammed T.
- Research ArticleOsteoarticular tissue infection and development of skeletal pathology in murine brucellosisDiogo M. Magnani, Elizabeth T. Lyons, Toni S. Forde, Mohammed T. Shekhani, Vyacheslav A. Adarichev, Gary A. SplitterDisease Models & Mechanisms 2013 6: 811-818; doi: 10.1242/dmm.011056
Siegel, Vivian
- EditorialProvoking progress: a new chapterVivian Siegel Founding Editor-in-ChiefDisease Models & Mechanisms 2013 6: 557-558; doi: 10.1242/dmm.012419
Simard, Jodie P.
- Research ArticleNeurons and cardiomyocytes derived from induced pluripotent stem cells as a model for mitochondrial defects in Friedreich’s ataxiaAurore Hick, Marie Wattenhofer-Donzé, Satyan Chintawar, Philippe Tropel, Jodie P. Simard, Nadège Vaucamps, David Gall, Laurie Lambot, Cécile André, Laurence Reutenauer, Myriam Rai, Marius Teletin, Nadia Messaddeq, Serge N. Schiffmann, Stéphane Viville, Christopher E. Pearson, Massimo Pandolfo, Hélène PuccioDisease Models & Mechanisms 2013 6: 608-621; doi: 10.1242/dmm.010900
Simons, Matias
- Research ArticleElevated expression of the V-ATPase C subunit triggers JNK-dependent cell invasion and overgrowth in a Drosophila epitheliumAstrid G. Petzoldt, Eva Maria Gleixner, Arianna Fumagalli, Thomas Vaccari, Matias SimonsDisease Models & Mechanisms 2013 6: 689-700; doi: 10.1242/dmm.010660
Sitthisak, Thongrong
- Research ArticleSepsis otopathy: experimental sepsis leads to significant hearing impairment due to apoptosis and glutamate excitotoxicity in murine cochleaJoachim Schmutzhard, Rudolf Glueckert, Christian Pritz, Michael J. F. Blumer, Mario Bitsche, Peter Lackner, Manfred Fille, Herbert Riechelmann, Matthias Harkamp, Thongrong Sitthisak, Annelies Schrott-FischerDisease Models & Mechanisms 2013 6: 745-754; doi: 10.1242/dmm.011205
Sleigh, James N.
- Research ArticleLoss of the E3 ubiquitin ligase LRSAM1 sensitizes peripheral axons to degeneration in a mouse model of Charcot-Marie-Tooth diseaseLaurent P. Bogdanik, James N. Sleigh, Cong Tian, Mark E. Samuels, Karen Bedard, Kevin L. Seburn, Robert W. BurgessDisease Models & Mechanisms 2013 6: 780-792; doi: 10.1242/dmm.010942
Slusarski, Diane C.
- Research ArticleMechanisms of prickle1a function in zebrafish epilepsy and retinal neurogenesisXue Mei, Shu Wu, Alexander G. Bassuk, Diane C. SlusarskiDisease Models & Mechanisms 2013 6: 679-688; doi: 10.1242/dmm.010793
Smith, James C.
- EditorialDeciphering the Mechanisms of Developmental Disorders (DMDD): a new programme for phenotyping embryonic lethal miceTimothy Mohun, David J. Adams, Richard Baldock, Shoumo Bhattacharya, Andrew J. Copp, Myriam Hemberger, Corinne Houart, Matt E. Hurles, Elizabeth Robertson, James C. Smith, Tom Weaver, Wolfgang WeningerDisease Models & Mechanisms 2013 6: 562-566; doi: 10.1242/dmm.011957
Spaink, Herman P.
- Resource ArticleFunctional analysis of a zebrafish myd88 mutant identifies key transcriptional components of the innate immune systemMichiel van der Vaart, Joost J. van Soest, Herman P. Spaink, Annemarie H. MeijerDisease Models & Mechanisms 2013 6: 841-854; doi: 10.1242/dmm.010843
Splitter, Gary A.
- Research ArticleOsteoarticular tissue infection and development of skeletal pathology in murine brucellosisDiogo M. Magnani, Elizabeth T. Lyons, Toni S. Forde, Mohammed T. Shekhani, Vyacheslav A. Adarichev, Gary A. SplitterDisease Models & Mechanisms 2013 6: 811-818; doi: 10.1242/dmm.011056
Stanescu, Horia C.
- Research ArticleGeneration and validation of a zebrafish model of EAST (epilepsy, ataxia, sensorineural deafness and tubulopathy) syndromeFahad Mahmood, Monika Mozere, Anselm A. Zdebik, Horia C. Stanescu, Jonathan Tobin, Philip L. Beales, Robert Kleta, Detlef Bockenhauer, Claire RussellDisease Models & Mechanisms 2013 6: 652-660; doi: 10.1242/dmm.009480
Subramanian, Manivannan
- Research ArticleAltered lipid homeostasis in Drosophila InsP3 receptor mutants leads to obesity and hyperphagiaManivannan Subramanian, Suman Kumar Metya, Sufia Sadaf, Satish Kumar, Dominik Schwudke, Gaiti HasanDisease Models & Mechanisms 2013 6: 734-744; doi: 10.1242/dmm.010017
Sukhina, Alona S.
- Research ArticleMotor neurons and glia exhibit specific individualized responses to TDP-43 expression in a Drosophila model of amyotrophic lateral sclerosisPatricia S. Estes, Scott G. Daniel, Abigail P. Mccallum, Ashley V. Boehringer, Alona S. Sukhina, Rebecca A. Zwick, Daniela C. ZarnescuDisease Models & Mechanisms 2013 6: 721-733; doi: 10.1242/dmm.010710
Suuronen, Erik J.
- Research ArticleA necrotic stimulus is required to maximize matrix-mediated myogenesis in miceDrew Kuraitis, Maria Grazia Berardinelli, Erik J. Suuronen, Antonio MusaròDisease Models & Mechanisms 2013 6: 793-801; doi: 10.1242/dmm.011072
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Teletin, Marius
- Research ArticleNeurons and cardiomyocytes derived from induced pluripotent stem cells as a model for mitochondrial defects in Friedreich’s ataxiaAurore Hick, Marie Wattenhofer-Donzé, Satyan Chintawar, Philippe Tropel, Jodie P. Simard, Nadège Vaucamps, David Gall, Laurie Lambot, Cécile André, Laurence Reutenauer, Myriam Rai, Marius Teletin, Nadia Messaddeq, Serge N. Schiffmann, Stéphane Viville, Christopher E. Pearson, Massimo Pandolfo, Hélène PuccioDisease Models & Mechanisms 2013 6: 608-621; doi: 10.1242/dmm.010900
Thiemermann, Christoph
- Research ArticlePharmacological preconditioning with erythropoietin attenuates the organ injury and dysfunction induced in a rat model of hemorrhagic shockKiran K. Nandra, Massimo Collino, Mara Rogazzo, Roberto Fantozzi, Nimesh S. A. Patel, Christoph ThiemermannDisease Models & Mechanisms 2013 6: 701-709; doi: 10.1242/dmm.011353
Thompson, Amelia J.
- Research ArticleA murine Zic3 transcript with a premature termination codon evades nonsense-mediated decay during axis formationJehangir N. Ahmed, Radiya G. Ali, Nicholas Warr, Heather M. Wilson, Helen M. Bellchambers, Kristen S. Barratt, Amelia J. Thompson, Ruth M. ArkellDisease Models & Mechanisms 2013 6: 755-767; doi: 10.1242/dmm.011668
Tian, Cong
- Research ArticleLoss of the E3 ubiquitin ligase LRSAM1 sensitizes peripheral axons to degeneration in a mouse model of Charcot-Marie-Tooth diseaseLaurent P. Bogdanik, James N. Sleigh, Cong Tian, Mark E. Samuels, Karen Bedard, Kevin L. Seburn, Robert W. BurgessDisease Models & Mechanisms 2013 6: 780-792; doi: 10.1242/dmm.010942
Tidmarsh, George F.
- EditorialBridging the gap between basic and applied biology: towards preclinical translationRoss L. Cagan, Monica J. Justice, George F. TidmarshDisease Models & Mechanisms 2013 6: 559-561; doi: 10.1242/dmm.012450
Tobin, Jonathan
- Research ArticleGeneration and validation of a zebrafish model of EAST (epilepsy, ataxia, sensorineural deafness and tubulopathy) syndromeFahad Mahmood, Monika Mozere, Anselm A. Zdebik, Horia C. Stanescu, Jonathan Tobin, Philip L. Beales, Robert Kleta, Detlef Bockenhauer, Claire RussellDisease Models & Mechanisms 2013 6: 652-660; doi: 10.1242/dmm.009480
Tropel, Philippe
- Research ArticleNeurons and cardiomyocytes derived from induced pluripotent stem cells as a model for mitochondrial defects in Friedreich’s ataxiaAurore Hick, Marie Wattenhofer-Donzé, Satyan Chintawar, Philippe Tropel, Jodie P. Simard, Nadège Vaucamps, David Gall, Laurie Lambot, Cécile André, Laurence Reutenauer, Myriam Rai, Marius Teletin, Nadia Messaddeq, Serge N. Schiffmann, Stéphane Viville, Christopher E. Pearson, Massimo Pandolfo, Hélène PuccioDisease Models & Mechanisms 2013 6: 608-621; doi: 10.1242/dmm.010900
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Vaccari, Thomas
- Research ArticleElevated expression of the V-ATPase C subunit triggers JNK-dependent cell invasion and overgrowth in a Drosophila epitheliumAstrid G. Petzoldt, Eva Maria Gleixner, Arianna Fumagalli, Thomas Vaccari, Matias SimonsDisease Models & Mechanisms 2013 6: 689-700; doi: 10.1242/dmm.010660
van der Vaart, Michiel
- Resource ArticleFunctional analysis of a zebrafish myd88 mutant identifies key transcriptional components of the innate immune systemMichiel van der Vaart, Joost J. van Soest, Herman P. Spaink, Annemarie H. MeijerDisease Models & Mechanisms 2013 6: 841-854; doi: 10.1242/dmm.010843
van Soest, Joost J.
- Resource ArticleFunctional analysis of a zebrafish myd88 mutant identifies key transcriptional components of the innate immune systemMichiel van der Vaart, Joost J. van Soest, Herman P. Spaink, Annemarie H. MeijerDisease Models & Mechanisms 2013 6: 841-854; doi: 10.1242/dmm.010843
Vaucamps, Nadège
- Research ArticleNeurons and cardiomyocytes derived from induced pluripotent stem cells as a model for mitochondrial defects in Friedreich’s ataxiaAurore Hick, Marie Wattenhofer-Donzé, Satyan Chintawar, Philippe Tropel, Jodie P. Simard, Nadège Vaucamps, David Gall, Laurie Lambot, Cécile André, Laurence Reutenauer, Myriam Rai, Marius Teletin, Nadia Messaddeq, Serge N. Schiffmann, Stéphane Viville, Christopher E. Pearson, Massimo Pandolfo, Hélène PuccioDisease Models & Mechanisms 2013 6: 608-621; doi: 10.1242/dmm.010900
Viville, Stéphane
- Research ArticleNeurons and cardiomyocytes derived from induced pluripotent stem cells as a model for mitochondrial defects in Friedreich’s ataxiaAurore Hick, Marie Wattenhofer-Donzé, Satyan Chintawar, Philippe Tropel, Jodie P. Simard, Nadège Vaucamps, David Gall, Laurie Lambot, Cécile André, Laurence Reutenauer, Myriam Rai, Marius Teletin, Nadia Messaddeq, Serge N. Schiffmann, Stéphane Viville, Christopher E. Pearson, Massimo Pandolfo, Hélène PuccioDisease Models & Mechanisms 2013 6: 608-621; doi: 10.1242/dmm.010900
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Wang, Xiaoting
- Resource ArticleAn entirely automated method to score DSS-induced colitis in mice by digital image analysis of pathology slidesCleopatra Kozlowski, Surinder Jeet, Joseph Beyer, Steve Guerrero, Justin Lesch, Xiaoting Wang, Jason DeVoss, Lauri DiehlDisease Models & Mechanisms 2013 6: 855-865; doi: 10.1242/dmm.011759
Wang, Yingli
- Research ArticleFrom shape to cells: mouse models reveal mechanisms altering palate development in Apert syndromeNeus Martínez-Abadías, Greg Holmes, Talia Pankratz, Yingli Wang, Xueyan Zhou, Ethylin Wang Jabs, Joan T. RichtsmeierDisease Models & Mechanisms 2013 6: 768-779; doi: 10.1242/dmm.010397
Ward, Nora M.
- Research ReportBehavioral abnormalities and Parkinson’s-like histological changes resulting from Id2 inactivation in miceMatthew C. Havrda, Brenton R. Paolella, Nora M. Ward, Kathryn B. HolroydDisease Models & Mechanisms 2013 6: 819-827; doi: 10.1242/dmm.010041
Warr, Nicholas
- Research ArticleA murine Zic3 transcript with a premature termination codon evades nonsense-mediated decay during axis formationJehangir N. Ahmed, Radiya G. Ali, Nicholas Warr, Heather M. Wilson, Helen M. Bellchambers, Kristen S. Barratt, Amelia J. Thompson, Ruth M. ArkellDisease Models & Mechanisms 2013 6: 755-767; doi: 10.1242/dmm.011668
Wattenhofer-Donzé, Marie
- Research ArticleNeurons and cardiomyocytes derived from induced pluripotent stem cells as a model for mitochondrial defects in Friedreich’s ataxiaAurore Hick, Marie Wattenhofer-Donzé, Satyan Chintawar, Philippe Tropel, Jodie P. Simard, Nadège Vaucamps, David Gall, Laurie Lambot, Cécile André, Laurence Reutenauer, Myriam Rai, Marius Teletin, Nadia Messaddeq, Serge N. Schiffmann, Stéphane Viville, Christopher E. Pearson, Massimo Pandolfo, Hélène PuccioDisease Models & Mechanisms 2013 6: 608-621; doi: 10.1242/dmm.010900
Weaver, Tom
- EditorialDeciphering the Mechanisms of Developmental Disorders (DMDD): a new programme for phenotyping embryonic lethal miceTimothy Mohun, David J. Adams, Richard Baldock, Shoumo Bhattacharya, Andrew J. Copp, Myriam Hemberger, Corinne Houart, Matt E. Hurles, Elizabeth Robertson, James C. Smith, Tom Weaver, Wolfgang WeningerDisease Models & Mechanisms 2013 6: 562-566; doi: 10.1242/dmm.011957
- Special ArticleBloomsbury report on mouse embryo phenotyping: recommendations from the IMPC workshop on embryonic lethal screeningDavid Adams, Richard Baldock, Shoumo Bhattacharya, Andrew J. Copp, Mary Dickinson, Nicholas D. E. Greene, Mark Henkelman, Monica Justice, Timothy Mohun, Stephen A. Murray, Erwin Pauws, Michael Raess, Janet Rossant, Tom Weaver, David WestDisease Models & Mechanisms 2013 6: 571-579; doi: 10.1242/dmm.011833
Weninger, Wolfgang
- EditorialDeciphering the Mechanisms of Developmental Disorders (DMDD): a new programme for phenotyping embryonic lethal miceTimothy Mohun, David J. Adams, Richard Baldock, Shoumo Bhattacharya, Andrew J. Copp, Myriam Hemberger, Corinne Houart, Matt E. Hurles, Elizabeth Robertson, James C. Smith, Tom Weaver, Wolfgang WeningerDisease Models & Mechanisms 2013 6: 562-566; doi: 10.1242/dmm.011957
West, David
- Special ArticleBloomsbury report on mouse embryo phenotyping: recommendations from the IMPC workshop on embryonic lethal screeningDavid Adams, Richard Baldock, Shoumo Bhattacharya, Andrew J. Copp, Mary Dickinson, Nicholas D. E. Greene, Mark Henkelman, Monica Justice, Timothy Mohun, Stephen A. Murray, Erwin Pauws, Michael Raess, Janet Rossant, Tom Weaver, David WestDisease Models & Mechanisms 2013 6: 571-579; doi: 10.1242/dmm.011833
Willoughby, Lee
- Research ArticleIn Drosophila, RhoGEF2 cooperates with activated Ras in tumorigenesis through a pathway involving Rho1–Rok–Myosin-II and JNK signallingPeytee Khoo, Kirsten Allan, Lee Willoughby, Anthony M. Brumby, Helena E. RichardsonDisease Models & Mechanisms 2013 6: 661-678; doi: 10.1242/dmm.010066
Wilson, Heather M.
- Research ArticleA murine Zic3 transcript with a premature termination codon evades nonsense-mediated decay during axis formationJehangir N. Ahmed, Radiya G. Ali, Nicholas Warr, Heather M. Wilson, Helen M. Bellchambers, Kristen S. Barratt, Amelia J. Thompson, Ruth M. ArkellDisease Models & Mechanisms 2013 6: 755-767; doi: 10.1242/dmm.011668
Wu, Shu
- Research ArticleMechanisms of prickle1a function in zebrafish epilepsy and retinal neurogenesisXue Mei, Shu Wu, Alexander G. Bassuk, Diane C. SlusarskiDisease Models & Mechanisms 2013 6: 679-688; doi: 10.1242/dmm.010793
Wu, Xiaohui
- Research ReportpiggyBac as a high-capacity transgenesis and gene-therapy vector in human cells and miceRongbo Li, Yuan Zhuang, Min Han, Tian Xu, Xiaohui WuDisease Models & Mechanisms 2013 6: 828-833; doi: 10.1242/dmm.010827
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Xu, Tian
- Research ReportpiggyBac as a high-capacity transgenesis and gene-therapy vector in human cells and miceRongbo Li, Yuan Zhuang, Min Han, Tian Xu, Xiaohui WuDisease Models & Mechanisms 2013 6: 828-833; doi: 10.1242/dmm.010827
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Zarnescu, Daniela C.
- Research ArticleMotor neurons and glia exhibit specific individualized responses to TDP-43 expression in a Drosophila model of amyotrophic lateral sclerosisPatricia S. Estes, Scott G. Daniel, Abigail P. Mccallum, Ashley V. Boehringer, Alona S. Sukhina, Rebecca A. Zwick, Daniela C. ZarnescuDisease Models & Mechanisms 2013 6: 721-733; doi: 10.1242/dmm.010710
Zdebik, Anselm A.
- Research ArticleGeneration and validation of a zebrafish model of EAST (epilepsy, ataxia, sensorineural deafness and tubulopathy) syndromeFahad Mahmood, Monika Mozere, Anselm A. Zdebik, Horia C. Stanescu, Jonathan Tobin, Philip L. Beales, Robert Kleta, Detlef Bockenhauer, Claire RussellDisease Models & Mechanisms 2013 6: 652-660; doi: 10.1242/dmm.009480
Zhou, Xueyan
- Research ArticleFrom shape to cells: mouse models reveal mechanisms altering palate development in Apert syndromeNeus Martínez-Abadías, Greg Holmes, Talia Pankratz, Yingli Wang, Xueyan Zhou, Ethylin Wang Jabs, Joan T. RichtsmeierDisease Models & Mechanisms 2013 6: 768-779; doi: 10.1242/dmm.010397
Zhuang, Yuan
- Research ReportpiggyBac as a high-capacity transgenesis and gene-therapy vector in human cells and miceRongbo Li, Yuan Zhuang, Min Han, Tian Xu, Xiaohui WuDisease Models & Mechanisms 2013 6: 828-833; doi: 10.1242/dmm.010827
Zwick, Rebecca A.
- Research ArticleMotor neurons and glia exhibit specific individualized responses to TDP-43 expression in a Drosophila model of amyotrophic lateral sclerosisPatricia S. Estes, Scott G. Daniel, Abigail P. Mccallum, Ashley V. Boehringer, Alona S. Sukhina, Rebecca A. Zwick, Daniela C. ZarnescuDisease Models & Mechanisms 2013 6: 721-733; doi: 10.1242/dmm.010710

- Open Access
Altered cytoskeletal arrangement in induced pluripotent stem cells (iPSCs) and motor neurons from patients with riboflavin transporter deficiency
Alessia Niceforo, Chiara Marioli, Fiorella Colasuonno, Stefania Petrini, Keith Massey, Marco Tartaglia, Enrico Bertini, Sandra Moreno, Claudia Compagnucci - Open Access
Genetic background modifies vulnerability to glaucoma related phenotypes in Lmx1b mutant mice
N. G. Tolman, R. Balasubramanian, D. G. Macalinao, A. L. Kearney, K. H. MacNicoll, C. L. Montgomery, W. N. de Vries, I. J. Jackson, S. H. Cross, K. Kizhatil, K. S. Nair, S. W. M. John - Open Access
Neural crest-specific deletion of Bmp7 leads to midfacial hypoplasia, nasal airway obstruction, and disordered breathing modelling Obstructive Sleep Apnea
Pranidhi Baddam, Vivian Biancardi, Daniela M. Roth, Farah Eaton, Claudine Thereza-Bussolaro, Rupasri Mandal, David S. Wishart, Amy Barr, Joanna MacLean, Carlos Flores-Mir, Silvia Pagliardini, Daniel Graf - Open Access
Inducible expression of human C9ORF72 36x G4C2 hexanucleotide repeats is sufficient to cause RAN translation and rapid muscular atrophy in mice
F. W. Riemslagh, E. C. van der Toorn, R. F. M. Verhagen, A. Maas, L. W. J. Bosman, R. K. Hukema, R. Willemsen - Open Access
A muscle growth promoting treatment based on the attenuation of activin/myostatin signalling in young mice results in long-term testicular abnormalities
Danielle Vaughan, Robert Mitchell, Oliver Kretz, David Chambers, Maciej Lalowski, Helge Amthor, Olli Ritvos, Arja Pasternack, Antonios Matsakas, Sakthivel Vaiyapuri, Tobias B. Huber, Bernd Denecke, Abir Mukherjee, Darius Widera, Ketan Patel
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DMM and COVID-19
We are aware that the COVID-19 pandemic is having an unprecedented impact on researchers worldwide. The Editors of all The Company of Biologists’ journals have been considering ways in which we can alleviate concerns that members of our community may have around publishing activities during this time. Read about the actions we are taking at this time.
Please don’t hesitate to contact the Editorial Office if you have any questions or concerns.
Professor Elizabeth Patton appointed as DMM’s next Editor-in-Chief
We are pleased to announce that The Company of Biologists directors have appointed Professor Elizabeth Patton as DMM's new Editor-in-Chief. As Paresh Vyas writes in his Editorial, Liz ‘brings vitality and a passion for the remit of DMM, and is deeply embedded in the community.’
Did you know DMM Conference Travel Grants can be used for online meetings?
With travel restrictions still in place, we want to continue supporting early-career researchers in their careers. DMM’s Conference Travel Grants can now be used to attend virtual and online scientific meetings, workshops, conferences and training courses.
The current application round closes on 8 February 2021 – find out more.
Identification of MYOM2 as a candidate gene in hypertrophic cardiomyopathy and Tetralogy of Fallot, and its functional evaluation in the Drosophila heart
Research from Silke Sperling and colleagues uses Drosophila to identify MYOM2 as a candidate gene in congenital heart malformations in this issue’s Editor’s choice.
C. elegans as a disease model
A new Research article from Doyle et al., models spinal muscular atrophy in C. elegans to show that that targeting therapies to muscle cells is more effective than neuronal delivery. Find more research using C. elegans as a disease model in our latest subject collection.
Call for papers – The RAS Pathway: Diseases, Therapeutics and Beyond
Our upcoming special issue is now welcoming submissions until 1 April 2021. Guest-edited by Donita Brady (Perelman School of Medicine at the University of Pennsylvania, USA) and Arvin Dar (Icahn School of Medicine at Mount Sinai, USA), the issue will focus on the targeting the RAS pathway. Find out more about the issue and how to submit your manuscript.
Interview – Kim Landry-Truchon and Nicolas Houde
In an interview, first authors Kim Landry-Truchon and Nicolas Houde discuss their mouse model of the early stages of pleuropulmonary blastoma, reflecting on the implications of their work and the future of their field.