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March 1, 2012; 5 (2)

A

  1. Aalto-Setälä, Katriina

    1. Research Article
      Model for long QT syndrome type 2 using human iPS cells demonstrates arrhythmogenic characteristics in cell culture
      Anna L. Lahti, Ville J. Kujala, Hugh Chapman, Ari-Pekka Koivisto, Mari Pekkanen-Mattila, Erja Kerkelä, Jari Hyttinen, Kimmo Kontula, Heikki Swan, Bruce R. Conklin, Shinya Yamanaka, Olli Silvennoinen, Katriina Aalto-Setälä
      Disease Models & Mechanisms 2012 5: 220-230; doi: 10.1242/dmm.008409

C

  1. Chaieb, Leila

    1. Research Article
      Conserved valproic-acid-induced lipid droplet formation in Dictyostelium and human hepatocytes identifies structurally active compounds
      Lucy M. Elphick, Nadine Pawolleck, Irina A. Guschina, Leila Chaieb, Daniel Eikel, Heinz Nau, John L. Harwood, Nick J. Plant, Robin S. B. Williams
      Disease Models & Mechanisms 2012 5: 231-240; doi: 10.1242/dmm.008391

  2. Chan, Chun-Hung

    1. Research Article
      BTN1, the Saccharomyces cerevisiae homolog to the human Batten disease gene, is involved in phospholipid distribution
      Sergio Padilla-López, Deanna Langager, Chun-Hung Chan, David A. Pearce
      Disease Models & Mechanisms 2012 5: 191-199; doi: 10.1242/dmm.008490

  3. Chapman, Hugh

    1. Research Article
      Model for long QT syndrome type 2 using human iPS cells demonstrates arrhythmogenic characteristics in cell culture
      Anna L. Lahti, Ville J. Kujala, Hugh Chapman, Ari-Pekka Koivisto, Mari Pekkanen-Mattila, Erja Kerkelä, Jari Hyttinen, Kimmo Kontula, Heikki Swan, Bruce R. Conklin, Shinya Yamanaka, Olli Silvennoinen, Katriina Aalto-Setälä
      Disease Models & Mechanisms 2012 5: 220-230; doi: 10.1242/dmm.008409

  4. Choorapoikayil, Suma

    1. Research Article
      Haploinsufficiency of the genes encoding the tumor suppressor Pten predisposes zebrafish to hemangiosarcoma
      Suma Choorapoikayil, Raoul V. Kuiper, Alain de Bruin, Jeroen den Hertog
      Disease Models & Mechanisms 2012 5: 241-247; doi: 10.1242/dmm.008326

  5. Conklin, Bruce R.

    1. Research Article
      Model for long QT syndrome type 2 using human iPS cells demonstrates arrhythmogenic characteristics in cell culture
      Anna L. Lahti, Ville J. Kujala, Hugh Chapman, Ari-Pekka Koivisto, Mari Pekkanen-Mattila, Erja Kerkelä, Jari Hyttinen, Kimmo Kontula, Heikki Swan, Bruce R. Conklin, Shinya Yamanaka, Olli Silvennoinen, Katriina Aalto-Setälä
      Disease Models & Mechanisms 2012 5: 220-230; doi: 10.1242/dmm.008409

D

  1. de Bruin, Alain

    1. Research Article
      Haploinsufficiency of the genes encoding the tumor suppressor Pten predisposes zebrafish to hemangiosarcoma
      Suma Choorapoikayil, Raoul V. Kuiper, Alain de Bruin, Jeroen den Hertog
      Disease Models & Mechanisms 2012 5: 241-247; doi: 10.1242/dmm.008326

  2. De la Rosa, Mitche

    1. Research Article
      Excessive activity of cathepsin K is associated with cartilage defects in a zebrafish model of mucolipidosis II
      Aaron C. Petrey, Heather Flanagan-Steet, Steven Johnson, Xiang Fan, Mitche De la Rosa, Mark E. Haskins, Alison V. Nairn, Kelley W. Moremen, Richard Steet
      Disease Models & Mechanisms 2012 5: 177-190; doi: 10.1242/dmm.008219

  3. den Hertog, Jeroen

    1. Research Article
      Haploinsufficiency of the genes encoding the tumor suppressor Pten predisposes zebrafish to hemangiosarcoma
      Suma Choorapoikayil, Raoul V. Kuiper, Alain de Bruin, Jeroen den Hertog
      Disease Models & Mechanisms 2012 5: 241-247; doi: 10.1242/dmm.008326

  4. Downes, Gerald B.

    1. Research Article
      Mutation of zebrafish dihydrolipoamide branched-chain transacylase E2 results in motor dysfunction and models maple syrup urine disease
      Timo Friedrich, Aaron M. Lambert, Mark A. Masino, Gerald B. Downes
      Disease Models & Mechanisms 2012 5: 248-258; doi: 10.1242/dmm.008383

E

  1. Eikel, Daniel

    1. Research Article
      Conserved valproic-acid-induced lipid droplet formation in Dictyostelium and human hepatocytes identifies structurally active compounds
      Lucy M. Elphick, Nadine Pawolleck, Irina A. Guschina, Leila Chaieb, Daniel Eikel, Heinz Nau, John L. Harwood, Nick J. Plant, Robin S. B. Williams
      Disease Models & Mechanisms 2012 5: 231-240; doi: 10.1242/dmm.008391

  2. Elphick, Lucy M.

    1. Research Article
      Conserved valproic-acid-induced lipid droplet formation in Dictyostelium and human hepatocytes identifies structurally active compounds
      Lucy M. Elphick, Nadine Pawolleck, Irina A. Guschina, Leila Chaieb, Daniel Eikel, Heinz Nau, John L. Harwood, Nick J. Plant, Robin S. B. Williams
      Disease Models & Mechanisms 2012 5: 231-240; doi: 10.1242/dmm.008391

F

  1. Fan, Xiang

    1. Research Article
      Excessive activity of cathepsin K is associated with cartilage defects in a zebrafish model of mucolipidosis II
      Aaron C. Petrey, Heather Flanagan-Steet, Steven Johnson, Xiang Fan, Mitche De la Rosa, Mark E. Haskins, Alison V. Nairn, Kelley W. Moremen, Richard Steet
      Disease Models & Mechanisms 2012 5: 177-190; doi: 10.1242/dmm.008219

  2. Flanagan-Steet, Heather

    1. Research Article
      Excessive activity of cathepsin K is associated with cartilage defects in a zebrafish model of mucolipidosis II
      Aaron C. Petrey, Heather Flanagan-Steet, Steven Johnson, Xiang Fan, Mitche De la Rosa, Mark E. Haskins, Alison V. Nairn, Kelley W. Moremen, Richard Steet
      Disease Models & Mechanisms 2012 5: 177-190; doi: 10.1242/dmm.008219

  3. Friedrich, Timo

    1. Research Article
      Mutation of zebrafish dihydrolipoamide branched-chain transacylase E2 results in motor dysfunction and models maple syrup urine disease
      Timo Friedrich, Aaron M. Lambert, Mark A. Masino, Gerald B. Downes
      Disease Models & Mechanisms 2012 5: 248-258; doi: 10.1242/dmm.008383

G

  1. Giniger, Edward

    1. Research Article
      Absence of the Cdk5 activator p35 causes adult-onset neurodegeneration in the central brain of Drosophila
      Svetlana Trunova, Edward Giniger
      Disease Models & Mechanisms 2012 5: 210-219; doi: 10.1242/dmm.008847

  2. Guschina, Irina A.

    1. Research Article
      Conserved valproic-acid-induced lipid droplet formation in Dictyostelium and human hepatocytes identifies structurally active compounds
      Lucy M. Elphick, Nadine Pawolleck, Irina A. Guschina, Leila Chaieb, Daniel Eikel, Heinz Nau, John L. Harwood, Nick J. Plant, Robin S. B. Williams
      Disease Models & Mechanisms 2012 5: 231-240; doi: 10.1242/dmm.008391

H

  1. Harwood, John L.

    1. Research Article
      Conserved valproic-acid-induced lipid droplet formation in Dictyostelium and human hepatocytes identifies structurally active compounds
      Lucy M. Elphick, Nadine Pawolleck, Irina A. Guschina, Leila Chaieb, Daniel Eikel, Heinz Nau, John L. Harwood, Nick J. Plant, Robin S. B. Williams
      Disease Models & Mechanisms 2012 5: 231-240; doi: 10.1242/dmm.008391

  2. Haskins, Mark E.

    1. Research Article
      Excessive activity of cathepsin K is associated with cartilage defects in a zebrafish model of mucolipidosis II
      Aaron C. Petrey, Heather Flanagan-Steet, Steven Johnson, Xiang Fan, Mitche De la Rosa, Mark E. Haskins, Alison V. Nairn, Kelley W. Moremen, Richard Steet
      Disease Models & Mechanisms 2012 5: 177-190; doi: 10.1242/dmm.008219

  3. Hori, Motohide

    1. Resource Article
      Unraveling the ischemic brain transcriptome in a permanent middle cerebral artery occlusion mouse model by DNA microarray analysis
      Motohide Hori, Tomoya Nakamachi, Randeep Rakwal, Junko Shibato, Keisuke Nakamura, Yoshihiro Wada, Daisuke Tsuchikawa, Akira Yoshikawa, Keiji Tamaki, Seiji Shioda
      Disease Models & Mechanisms 2012 5: 270-283; doi: 10.1242/dmm.008276

  4. Hyttinen, Jari

    1. Research Article
      Model for long QT syndrome type 2 using human iPS cells demonstrates arrhythmogenic characteristics in cell culture
      Anna L. Lahti, Ville J. Kujala, Hugh Chapman, Ari-Pekka Koivisto, Mari Pekkanen-Mattila, Erja Kerkelä, Jari Hyttinen, Kimmo Kontula, Heikki Swan, Bruce R. Conklin, Shinya Yamanaka, Olli Silvennoinen, Katriina Aalto-Setälä
      Disease Models & Mechanisms 2012 5: 220-230; doi: 10.1242/dmm.008409

J

  1. Johnson, Steven

    1. Research Article
      Excessive activity of cathepsin K is associated with cartilage defects in a zebrafish model of mucolipidosis II
      Aaron C. Petrey, Heather Flanagan-Steet, Steven Johnson, Xiang Fan, Mitche De la Rosa, Mark E. Haskins, Alison V. Nairn, Kelley W. Moremen, Richard Steet
      Disease Models & Mechanisms 2012 5: 177-190; doi: 10.1242/dmm.008219

K

  1. Kerkelä, Erja

    1. Research Article
      Model for long QT syndrome type 2 using human iPS cells demonstrates arrhythmogenic characteristics in cell culture
      Anna L. Lahti, Ville J. Kujala, Hugh Chapman, Ari-Pekka Koivisto, Mari Pekkanen-Mattila, Erja Kerkelä, Jari Hyttinen, Kimmo Kontula, Heikki Swan, Bruce R. Conklin, Shinya Yamanaka, Olli Silvennoinen, Katriina Aalto-Setälä
      Disease Models & Mechanisms 2012 5: 220-230; doi: 10.1242/dmm.008409

  2. Kishimoto, Norihito

    1. Research Article
      Neuronal regeneration in a zebrafish model of adult brain injury
      Norihito Kishimoto, Kohei Shimizu, Kazunobu Sawamoto
      Disease Models & Mechanisms 2012 5: 200-209; doi: 10.1242/dmm.007336

  3. Koivisto, Ari-Pekka

    1. Research Article
      Model for long QT syndrome type 2 using human iPS cells demonstrates arrhythmogenic characteristics in cell culture
      Anna L. Lahti, Ville J. Kujala, Hugh Chapman, Ari-Pekka Koivisto, Mari Pekkanen-Mattila, Erja Kerkelä, Jari Hyttinen, Kimmo Kontula, Heikki Swan, Bruce R. Conklin, Shinya Yamanaka, Olli Silvennoinen, Katriina Aalto-Setälä
      Disease Models & Mechanisms 2012 5: 220-230; doi: 10.1242/dmm.008409

  4. Kontula, Kimmo

    1. Research Article
      Model for long QT syndrome type 2 using human iPS cells demonstrates arrhythmogenic characteristics in cell culture
      Anna L. Lahti, Ville J. Kujala, Hugh Chapman, Ari-Pekka Koivisto, Mari Pekkanen-Mattila, Erja Kerkelä, Jari Hyttinen, Kimmo Kontula, Heikki Swan, Bruce R. Conklin, Shinya Yamanaka, Olli Silvennoinen, Katriina Aalto-Setälä
      Disease Models & Mechanisms 2012 5: 220-230; doi: 10.1242/dmm.008409

  5. Kuiper, Raoul V.

    1. Research Article
      Haploinsufficiency of the genes encoding the tumor suppressor Pten predisposes zebrafish to hemangiosarcoma
      Suma Choorapoikayil, Raoul V. Kuiper, Alain de Bruin, Jeroen den Hertog
      Disease Models & Mechanisms 2012 5: 241-247; doi: 10.1242/dmm.008326

  6. Kujala, Ville J.

    1. Research Article
      Model for long QT syndrome type 2 using human iPS cells demonstrates arrhythmogenic characteristics in cell culture
      Anna L. Lahti, Ville J. Kujala, Hugh Chapman, Ari-Pekka Koivisto, Mari Pekkanen-Mattila, Erja Kerkelä, Jari Hyttinen, Kimmo Kontula, Heikki Swan, Bruce R. Conklin, Shinya Yamanaka, Olli Silvennoinen, Katriina Aalto-Setälä
      Disease Models & Mechanisms 2012 5: 220-230; doi: 10.1242/dmm.008409

L

  1. Lahti, Anna L.

    1. Research Article
      Model for long QT syndrome type 2 using human iPS cells demonstrates arrhythmogenic characteristics in cell culture
      Anna L. Lahti, Ville J. Kujala, Hugh Chapman, Ari-Pekka Koivisto, Mari Pekkanen-Mattila, Erja Kerkelä, Jari Hyttinen, Kimmo Kontula, Heikki Swan, Bruce R. Conklin, Shinya Yamanaka, Olli Silvennoinen, Katriina Aalto-Setälä
      Disease Models & Mechanisms 2012 5: 220-230; doi: 10.1242/dmm.008409

  2. Lambert, Aaron M.

    1. Research Article
      Mutation of zebrafish dihydrolipoamide branched-chain transacylase E2 results in motor dysfunction and models maple syrup urine disease
      Timo Friedrich, Aaron M. Lambert, Mark A. Masino, Gerald B. Downes
      Disease Models & Mechanisms 2012 5: 248-258; doi: 10.1242/dmm.008383

  3. Langager, Deanna

    1. Research Article
      BTN1, the Saccharomyces cerevisiae homolog to the human Batten disease gene, is involved in phospholipid distribution
      Sergio Padilla-López, Deanna Langager, Chun-Hung Chan, David A. Pearce
      Disease Models & Mechanisms 2012 5: 191-199; doi: 10.1242/dmm.008490

M

  1. Martelli, Alain

    1. Perspective
      Understanding the genetic and molecular pathogenesis of Friedreich’s ataxia through animal and cellular models
      Alain Martelli, Marek Napierala, Hélène Puccio
      Disease Models & Mechanisms 2012 5: 165-176; doi: 10.1242/dmm.008706

  2. Masino, Mark A.

    1. Research Article
      Mutation of zebrafish dihydrolipoamide branched-chain transacylase E2 results in motor dysfunction and models maple syrup urine disease
      Timo Friedrich, Aaron M. Lambert, Mark A. Masino, Gerald B. Downes
      Disease Models & Mechanisms 2012 5: 248-258; doi: 10.1242/dmm.008383

  3. Moremen, Kelley W.

    1. Research Article
      Excessive activity of cathepsin K is associated with cartilage defects in a zebrafish model of mucolipidosis II
      Aaron C. Petrey, Heather Flanagan-Steet, Steven Johnson, Xiang Fan, Mitche De la Rosa, Mark E. Haskins, Alison V. Nairn, Kelley W. Moremen, Richard Steet
      Disease Models & Mechanisms 2012 5: 177-190; doi: 10.1242/dmm.008219

N

  1. Nairn, Alison V.

    1. Research Article
      Excessive activity of cathepsin K is associated with cartilage defects in a zebrafish model of mucolipidosis II
      Aaron C. Petrey, Heather Flanagan-Steet, Steven Johnson, Xiang Fan, Mitche De la Rosa, Mark E. Haskins, Alison V. Nairn, Kelley W. Moremen, Richard Steet
      Disease Models & Mechanisms 2012 5: 177-190; doi: 10.1242/dmm.008219

  2. Nakamachi, Tomoya

    1. Resource Article
      Unraveling the ischemic brain transcriptome in a permanent middle cerebral artery occlusion mouse model by DNA microarray analysis
      Motohide Hori, Tomoya Nakamachi, Randeep Rakwal, Junko Shibato, Keisuke Nakamura, Yoshihiro Wada, Daisuke Tsuchikawa, Akira Yoshikawa, Keiji Tamaki, Seiji Shioda
      Disease Models & Mechanisms 2012 5: 270-283; doi: 10.1242/dmm.008276

  3. Nakamura, Keisuke

    1. Resource Article
      Unraveling the ischemic brain transcriptome in a permanent middle cerebral artery occlusion mouse model by DNA microarray analysis
      Motohide Hori, Tomoya Nakamachi, Randeep Rakwal, Junko Shibato, Keisuke Nakamura, Yoshihiro Wada, Daisuke Tsuchikawa, Akira Yoshikawa, Keiji Tamaki, Seiji Shioda
      Disease Models & Mechanisms 2012 5: 270-283; doi: 10.1242/dmm.008276

  4. Napierala, Marek

    1. Perspective
      Understanding the genetic and molecular pathogenesis of Friedreich’s ataxia through animal and cellular models
      Alain Martelli, Marek Napierala, Hélène Puccio
      Disease Models & Mechanisms 2012 5: 165-176; doi: 10.1242/dmm.008706

  5. Nau, Heinz

    1. Research Article
      Conserved valproic-acid-induced lipid droplet formation in Dictyostelium and human hepatocytes identifies structurally active compounds
      Lucy M. Elphick, Nadine Pawolleck, Irina A. Guschina, Leila Chaieb, Daniel Eikel, Heinz Nau, John L. Harwood, Nick J. Plant, Robin S. B. Williams
      Disease Models & Mechanisms 2012 5: 231-240; doi: 10.1242/dmm.008391

P

  1. Padilla-López, Sergio

    1. Research Article
      BTN1, the Saccharomyces cerevisiae homolog to the human Batten disease gene, is involved in phospholipid distribution
      Sergio Padilla-López, Deanna Langager, Chun-Hung Chan, David A. Pearce
      Disease Models & Mechanisms 2012 5: 191-199; doi: 10.1242/dmm.008490

  2. Pawolleck, Nadine

    1. Research Article
      Conserved valproic-acid-induced lipid droplet formation in Dictyostelium and human hepatocytes identifies structurally active compounds
      Lucy M. Elphick, Nadine Pawolleck, Irina A. Guschina, Leila Chaieb, Daniel Eikel, Heinz Nau, John L. Harwood, Nick J. Plant, Robin S. B. Williams
      Disease Models & Mechanisms 2012 5: 231-240; doi: 10.1242/dmm.008391

  3. Pearce, David A.

    1. Research Article
      BTN1, the Saccharomyces cerevisiae homolog to the human Batten disease gene, is involved in phospholipid distribution
      Sergio Padilla-López, Deanna Langager, Chun-Hung Chan, David A. Pearce
      Disease Models & Mechanisms 2012 5: 191-199; doi: 10.1242/dmm.008490

  4. Pekkanen-Mattila, Mari

    1. Research Article
      Model for long QT syndrome type 2 using human iPS cells demonstrates arrhythmogenic characteristics in cell culture
      Anna L. Lahti, Ville J. Kujala, Hugh Chapman, Ari-Pekka Koivisto, Mari Pekkanen-Mattila, Erja Kerkelä, Jari Hyttinen, Kimmo Kontula, Heikki Swan, Bruce R. Conklin, Shinya Yamanaka, Olli Silvennoinen, Katriina Aalto-Setälä
      Disease Models & Mechanisms 2012 5: 220-230; doi: 10.1242/dmm.008409

  5. Petrey, Aaron C.

    1. Research Article
      Excessive activity of cathepsin K is associated with cartilage defects in a zebrafish model of mucolipidosis II
      Aaron C. Petrey, Heather Flanagan-Steet, Steven Johnson, Xiang Fan, Mitche De la Rosa, Mark E. Haskins, Alison V. Nairn, Kelley W. Moremen, Richard Steet
      Disease Models & Mechanisms 2012 5: 177-190; doi: 10.1242/dmm.008219

  6. Plant, Nick J.

    1. Research Article
      Conserved valproic-acid-induced lipid droplet formation in Dictyostelium and human hepatocytes identifies structurally active compounds
      Lucy M. Elphick, Nadine Pawolleck, Irina A. Guschina, Leila Chaieb, Daniel Eikel, Heinz Nau, John L. Harwood, Nick J. Plant, Robin S. B. Williams
      Disease Models & Mechanisms 2012 5: 231-240; doi: 10.1242/dmm.008391

  7. Poppe, Andrea

    1. Research Article
      Metformin differentially activates ER stress signaling pathways without inducing apoptosis
      Thomas Quentin, Michael Steinmetz, Andrea Poppe, Sven Thoms
      Disease Models & Mechanisms 2012 5: 259-269; doi: 10.1242/dmm.008110

  8. Puccio, Hélène

    1. Perspective
      Understanding the genetic and molecular pathogenesis of Friedreich’s ataxia through animal and cellular models
      Alain Martelli, Marek Napierala, Hélène Puccio
      Disease Models & Mechanisms 2012 5: 165-176; doi: 10.1242/dmm.008706

Q

  1. Quentin, Thomas

    1. Research Article
      Metformin differentially activates ER stress signaling pathways without inducing apoptosis
      Thomas Quentin, Michael Steinmetz, Andrea Poppe, Sven Thoms
      Disease Models & Mechanisms 2012 5: 259-269; doi: 10.1242/dmm.008110

R

  1. Rakwal, Randeep

    1. Resource Article
      Unraveling the ischemic brain transcriptome in a permanent middle cerebral artery occlusion mouse model by DNA microarray analysis
      Motohide Hori, Tomoya Nakamachi, Randeep Rakwal, Junko Shibato, Keisuke Nakamura, Yoshihiro Wada, Daisuke Tsuchikawa, Akira Yoshikawa, Keiji Tamaki, Seiji Shioda
      Disease Models & Mechanisms 2012 5: 270-283; doi: 10.1242/dmm.008276

  2. Rouault, Tracey A.

    1. Commentary
      Biogenesis of iron-sulfur clusters in mammalian cells: new insights and relevance to human disease
      Tracey A. Rouault
      Disease Models & Mechanisms 2012 5: 155-164; doi: 10.1242/dmm.009019

S

  1. Sawamoto, Kazunobu

    1. Research Article
      Neuronal regeneration in a zebrafish model of adult brain injury
      Norihito Kishimoto, Kohei Shimizu, Kazunobu Sawamoto
      Disease Models & Mechanisms 2012 5: 200-209; doi: 10.1242/dmm.007336

  2. Shibato, Junko

    1. Resource Article
      Unraveling the ischemic brain transcriptome in a permanent middle cerebral artery occlusion mouse model by DNA microarray analysis
      Motohide Hori, Tomoya Nakamachi, Randeep Rakwal, Junko Shibato, Keisuke Nakamura, Yoshihiro Wada, Daisuke Tsuchikawa, Akira Yoshikawa, Keiji Tamaki, Seiji Shioda
      Disease Models & Mechanisms 2012 5: 270-283; doi: 10.1242/dmm.008276

  3. Shimizu, Kohei

    1. Research Article
      Neuronal regeneration in a zebrafish model of adult brain injury
      Norihito Kishimoto, Kohei Shimizu, Kazunobu Sawamoto
      Disease Models & Mechanisms 2012 5: 200-209; doi: 10.1242/dmm.007336

  4. Shioda, Seiji

    1. Resource Article
      Unraveling the ischemic brain transcriptome in a permanent middle cerebral artery occlusion mouse model by DNA microarray analysis
      Motohide Hori, Tomoya Nakamachi, Randeep Rakwal, Junko Shibato, Keisuke Nakamura, Yoshihiro Wada, Daisuke Tsuchikawa, Akira Yoshikawa, Keiji Tamaki, Seiji Shioda
      Disease Models & Mechanisms 2012 5: 270-283; doi: 10.1242/dmm.008276

  5. Silvennoinen, Olli

    1. Research Article
      Model for long QT syndrome type 2 using human iPS cells demonstrates arrhythmogenic characteristics in cell culture
      Anna L. Lahti, Ville J. Kujala, Hugh Chapman, Ari-Pekka Koivisto, Mari Pekkanen-Mattila, Erja Kerkelä, Jari Hyttinen, Kimmo Kontula, Heikki Swan, Bruce R. Conklin, Shinya Yamanaka, Olli Silvennoinen, Katriina Aalto-Setälä
      Disease Models & Mechanisms 2012 5: 220-230; doi: 10.1242/dmm.008409

  6. Steet, Richard

    1. Research Article
      Excessive activity of cathepsin K is associated with cartilage defects in a zebrafish model of mucolipidosis II
      Aaron C. Petrey, Heather Flanagan-Steet, Steven Johnson, Xiang Fan, Mitche De la Rosa, Mark E. Haskins, Alison V. Nairn, Kelley W. Moremen, Richard Steet
      Disease Models & Mechanisms 2012 5: 177-190; doi: 10.1242/dmm.008219

  7. Steinmetz, Michael

    1. Research Article
      Metformin differentially activates ER stress signaling pathways without inducing apoptosis
      Thomas Quentin, Michael Steinmetz, Andrea Poppe, Sven Thoms
      Disease Models & Mechanisms 2012 5: 259-269; doi: 10.1242/dmm.008110

  8. Swan, Heikki

    1. Research Article
      Model for long QT syndrome type 2 using human iPS cells demonstrates arrhythmogenic characteristics in cell culture
      Anna L. Lahti, Ville J. Kujala, Hugh Chapman, Ari-Pekka Koivisto, Mari Pekkanen-Mattila, Erja Kerkelä, Jari Hyttinen, Kimmo Kontula, Heikki Swan, Bruce R. Conklin, Shinya Yamanaka, Olli Silvennoinen, Katriina Aalto-Setälä
      Disease Models & Mechanisms 2012 5: 220-230; doi: 10.1242/dmm.008409

T

  1. Tamaki, Keiji

    1. Resource Article
      Unraveling the ischemic brain transcriptome in a permanent middle cerebral artery occlusion mouse model by DNA microarray analysis
      Motohide Hori, Tomoya Nakamachi, Randeep Rakwal, Junko Shibato, Keisuke Nakamura, Yoshihiro Wada, Daisuke Tsuchikawa, Akira Yoshikawa, Keiji Tamaki, Seiji Shioda
      Disease Models & Mechanisms 2012 5: 270-283; doi: 10.1242/dmm.008276

  2. Thoms, Sven

    1. Research Article
      Metformin differentially activates ER stress signaling pathways without inducing apoptosis
      Thomas Quentin, Michael Steinmetz, Andrea Poppe, Sven Thoms
      Disease Models & Mechanisms 2012 5: 259-269; doi: 10.1242/dmm.008110

  3. Trunova, Svetlana

    1. Research Article
      Absence of the Cdk5 activator p35 causes adult-onset neurodegeneration in the central brain of Drosophila
      Svetlana Trunova, Edward Giniger
      Disease Models & Mechanisms 2012 5: 210-219; doi: 10.1242/dmm.008847

  4. Tsuchikawa, Daisuke

    1. Resource Article
      Unraveling the ischemic brain transcriptome in a permanent middle cerebral artery occlusion mouse model by DNA microarray analysis
      Motohide Hori, Tomoya Nakamachi, Randeep Rakwal, Junko Shibato, Keisuke Nakamura, Yoshihiro Wada, Daisuke Tsuchikawa, Akira Yoshikawa, Keiji Tamaki, Seiji Shioda
      Disease Models & Mechanisms 2012 5: 270-283; doi: 10.1242/dmm.008276

W

  1. Wada, Yoshihiro

    1. Resource Article
      Unraveling the ischemic brain transcriptome in a permanent middle cerebral artery occlusion mouse model by DNA microarray analysis
      Motohide Hori, Tomoya Nakamachi, Randeep Rakwal, Junko Shibato, Keisuke Nakamura, Yoshihiro Wada, Daisuke Tsuchikawa, Akira Yoshikawa, Keiji Tamaki, Seiji Shioda
      Disease Models & Mechanisms 2012 5: 270-283; doi: 10.1242/dmm.008276

  2. Williams, Robin S. B.

    1. Research Article
      Conserved valproic-acid-induced lipid droplet formation in Dictyostelium and human hepatocytes identifies structurally active compounds
      Lucy M. Elphick, Nadine Pawolleck, Irina A. Guschina, Leila Chaieb, Daniel Eikel, Heinz Nau, John L. Harwood, Nick J. Plant, Robin S. B. Williams
      Disease Models & Mechanisms 2012 5: 231-240; doi: 10.1242/dmm.008391

Y

  1. Yamanaka, Shinya

    1. Research Article
      Model for long QT syndrome type 2 using human iPS cells demonstrates arrhythmogenic characteristics in cell culture
      Anna L. Lahti, Ville J. Kujala, Hugh Chapman, Ari-Pekka Koivisto, Mari Pekkanen-Mattila, Erja Kerkelä, Jari Hyttinen, Kimmo Kontula, Heikki Swan, Bruce R. Conklin, Shinya Yamanaka, Olli Silvennoinen, Katriina Aalto-Setälä
      Disease Models & Mechanisms 2012 5: 220-230; doi: 10.1242/dmm.008409

  2. Yoshikawa, Akira

    1. Resource Article
      Unraveling the ischemic brain transcriptome in a permanent middle cerebral artery occlusion mouse model by DNA microarray analysis
      Motohide Hori, Tomoya Nakamachi, Randeep Rakwal, Junko Shibato, Keisuke Nakamura, Yoshihiro Wada, Daisuke Tsuchikawa, Akira Yoshikawa, Keiji Tamaki, Seiji Shioda
      Disease Models & Mechanisms 2012 5: 270-283; doi: 10.1242/dmm.008276
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First person — Andrew Scott Emmert and Eri Iwasawa

Eri and Andrew

In an interview, first authors Andrew Scott Emmert and Eri Iwasawa discuss their new paper on impaired CSF flow and neural differentiation in a rat model of hydrocephalus, their research process and plans for the future.

Wild-type worms and pmm-2 F125L/F125L worms

Ethan Perlstein and colleagues present two back-to-back articles. In the first, they describe how the diabetic neuropathy drug palrestat can ameliorate PMM2-CDG. The second identifies the FDA-approved aripiprazole as a clinical candidate for treating NGLY1 deficiency.

Read Murgia et al.’s new resource article describing a SILAC-based proteomics approach to quantify the unfolded protein response.

We're excited to be an affiliate journal for Review Commons, the ASAPbio/EMBO platform for high-quality journal-independent peer-review in the life sciences, which went live on 09 December.