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RESEARCH ARTICLE
A new mouse model of GLUT1 deficiency syndrome exhibits abnormal sleep-wake patterns and alterations of glucose kinetics in the brain
Tamio Furuse, Hiroshi Mizuma, Yuuki Hirose, Tomoko Kushida, Ikuko Yamada, Ikuo Miura, Hiroshi Masuya, Hiromasa Funato, Masashi Yanagisawa, Hirotaka Onoe, Shigeharu Wakana
Disease Models & Mechanisms 2019 12: dmm038828 doi: 10.1242/dmm.038828 Published 12 September 2019

Article Information

vol. 12 no. 9, dmm038828

DOI 
https://doi.org/10.1242/dmm.038828
PubMed 
31399478
Published By 
The Company of Biologists Ltd
Print ISSN 
1754-8403
Online ISSN 
1754-8411
History 
  • Received January 9, 2019
  • Accepted July 30, 2019
  • Published online September 12, 2019.
Posted online 
August 09, 2019
Copyright & Usage 
© 2019. Published by The Company of Biologists Ltd http://creativecommons.org/licenses/by/4.0This is an Open Access article distributed under the terms of the Creative Commons Attribution License (https://creativecommons.org/licenses/by/4.0), which permits unrestricted use, distribution and reproduction in any medium provided that the original work is properly attributed.

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Author Information

  1. Tamio Furuse1,‡,§,
  2. Hiroshi Mizuma2,‡,
  3. Yuuki Hirose3,
  4. Tomoko Kushida1,
  5. Ikuko Yamada1,
  6. Ikuo Miura1,
  7. Hiroshi Masuya4,
  8. Hiromasa Funato3,5,
  9. Masashi Yanagisawa3,6,7,
  10. Hirotaka Onoe8 and
  11. Shigeharu Wakana1,*
  1. 1Japan Mouse Clinic, RIKEN BioResource Research Center, Tsukuba, Ibaraki 305-0074, Japan
  2. 2Laboratory for Pathophysiological and Health Science, RIKEN Center for Biosystems Dynamics Research, Kobe, Hyogo 650-0047, Japan
  3. 3International Institute for Integrative Sleep Medicine (WPI-IIIS), University of Tsukuba, Ibaraki 305-8575, Japan
  4. 4Resource Advancement Unit, Integrated Bioresource Information Division, RIKEN BioResource Research Center, Tsukuba, Ibaraki 305-0074, Japan
  5. 5Department of Anatomy, School of Medicine, Faculty of Medicine, Toho University, Tokyo 143-8540, Japan
  6. 6Life Science Center for Survival Dynamics (TARA), University of Tsukuba, Ibaraki 305-8575, Japan
  7. 7Department of Molecular Genetics, University of Texas Southwestern Medical Center, Dallas, TX 75390, USA
  8. 8Human Brain Research Center, Kyoto University Graduate School of Medicine, Kyoto 606-8501, Japan
  1. ↵§Author for correspondence (tamio.furuse{at}riken.jp)

  • ↵* Present address: Institute of Biomedical Research and Innovation, Foundation for Biomedical Research and Innovation, Kobe 650-0047, Japan.

  • ↵‡ These authors contributed equally to this work

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RESEARCH ARTICLE
A new mouse model of GLUT1 deficiency syndrome exhibits abnormal sleep-wake patterns and alterations of glucose kinetics in the brain
Tamio Furuse, Hiroshi Mizuma, Yuuki Hirose, Tomoko Kushida, Ikuko Yamada, Ikuo Miura, Hiroshi Masuya, Hiromasa Funato, Masashi Yanagisawa, Hirotaka Onoe, Shigeharu Wakana
Disease Models & Mechanisms 2019 12: dmm038828 doi: 10.1242/dmm.038828 Published 12 September 2019
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