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RESEARCH ARTICLE
CRISPR/Cas9-mediated homology-directed repair by ssODNs in zebrafish induces complex mutational patterns resulting from genomic integration of repair-template fragments
Annekatrien Boel, Hanna De Saffel, Wouter Steyaert, Bert Callewaert, Anne De Paepe, Paul J. Coucke, Andy Willaert
Disease Models & Mechanisms 2018 11: dmm035352 doi: 10.1242/dmm.035352 Published 18 October 2018
Annekatrien Boel
Center for Medical Genetics, Department of Biomolecular Medicine, Ghent University, Corneel Heymanslaan 10, 9000 Ghent, Belgium
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  • ORCID record for Annekatrien Boel
Hanna De Saffel
Center for Medical Genetics, Department of Biomolecular Medicine, Ghent University, Corneel Heymanslaan 10, 9000 Ghent, Belgium
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Wouter Steyaert
Center for Medical Genetics, Department of Biomolecular Medicine, Ghent University, Corneel Heymanslaan 10, 9000 Ghent, Belgium
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Bert Callewaert
Center for Medical Genetics, Department of Biomolecular Medicine, Ghent University, Corneel Heymanslaan 10, 9000 Ghent, Belgium
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  • ORCID record for Bert Callewaert
Anne De Paepe
Center for Medical Genetics, Department of Biomolecular Medicine, Ghent University, Corneel Heymanslaan 10, 9000 Ghent, Belgium
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  • ORCID record for Anne De Paepe
Paul J. Coucke
Center for Medical Genetics, Department of Biomolecular Medicine, Ghent University, Corneel Heymanslaan 10, 9000 Ghent, Belgium
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Andy Willaert
Center for Medical Genetics, Department of Biomolecular Medicine, Ghent University, Corneel Heymanslaan 10, 9000 Ghent, Belgium
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Keywords

  • CRISPR/Cas9
  • HDR
  • Homology-directed repair
  • Zebrafish
  • Next-generation sequencing

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RESEARCH ARTICLE
CRISPR/Cas9-mediated homology-directed repair by ssODNs in zebrafish induces complex mutational patterns resulting from genomic integration of repair-template fragments
Annekatrien Boel, Hanna De Saffel, Wouter Steyaert, Bert Callewaert, Anne De Paepe, Paul J. Coucke, Andy Willaert
Disease Models & Mechanisms 2018 11: dmm035352 doi: 10.1242/dmm.035352 Published 18 October 2018
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RESEARCH ARTICLE
CRISPR/Cas9-mediated homology-directed repair by ssODNs in zebrafish induces complex mutational patterns resulting from genomic integration of repair-template fragments
Annekatrien Boel, Hanna De Saffel, Wouter Steyaert, Bert Callewaert, Anne De Paepe, Paul J. Coucke, Andy Willaert
Disease Models & Mechanisms 2018 11: dmm035352 doi: 10.1242/dmm.035352 Published 18 October 2018

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