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RESEARCH ARTICLE
Towards trans-diagnostic mechanisms in psychiatry: neurobehavioral profile of rats with a loss-of-function point mutation in the dopamine transporter gene
Valentina Vengeliene, Anton Bespalov, Martin Roßmanith, Sandra Horschitz, Stefan Berger, Ana L. Relo, Hamid R. Noori, Peggy Schneider, Thomas Enkel, Dusan Bartsch, Miriam Schneider, Berthold Behl, Anita C. Hansson, Patrick Schloss, Rainer Spanagel
Disease Models & Mechanisms 2017 10: 451-461; doi: 10.1242/dmm.027623
Valentina Vengeliene
1Institute of Psychopharmacology, Central Institute of Mental Health, Medical Faculty Mannheim, Heidelberg University, 68159 Mannheim, Germany
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Anton Bespalov
2Department of Neuroscience Research, AbbVie Deutschland GmbH & Co KG, 67061 Ludwigshafen, Germany
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Martin Roßmanith
1Institute of Psychopharmacology, Central Institute of Mental Health, Medical Faculty Mannheim, Heidelberg University, 68159 Mannheim, Germany
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Sandra Horschitz
3Department of Psychiatry and Psychotherapy, Central Institute of Mental Health, Medical Faculty Mannheim, Heidelberg University, 68159 Mannheim, Germany
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Stefan Berger
4Department of Molecular Biology, Central Institute of Mental Health, Medical Faculty Mannheim, Heidelberg University, 68159 Mannheim, Germany
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Ana L. Relo
2Department of Neuroscience Research, AbbVie Deutschland GmbH & Co KG, 67061 Ludwigshafen, Germany
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Hamid R. Noori
1Institute of Psychopharmacology, Central Institute of Mental Health, Medical Faculty Mannheim, Heidelberg University, 68159 Mannheim, Germany
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Peggy Schneider
1Institute of Psychopharmacology, Central Institute of Mental Health, Medical Faculty Mannheim, Heidelberg University, 68159 Mannheim, Germany
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Thomas Enkel
4Department of Molecular Biology, Central Institute of Mental Health, Medical Faculty Mannheim, Heidelberg University, 68159 Mannheim, Germany
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Dusan Bartsch
4Department of Molecular Biology, Central Institute of Mental Health, Medical Faculty Mannheim, Heidelberg University, 68159 Mannheim, Germany
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Miriam Schneider
1Institute of Psychopharmacology, Central Institute of Mental Health, Medical Faculty Mannheim, Heidelberg University, 68159 Mannheim, Germany
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Berthold Behl
2Department of Neuroscience Research, AbbVie Deutschland GmbH & Co KG, 67061 Ludwigshafen, Germany
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Anita C. Hansson
1Institute of Psychopharmacology, Central Institute of Mental Health, Medical Faculty Mannheim, Heidelberg University, 68159 Mannheim, Germany
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Patrick Schloss
3Department of Psychiatry and Psychotherapy, Central Institute of Mental Health, Medical Faculty Mannheim, Heidelberg University, 68159 Mannheim, Germany
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Rainer Spanagel
1Institute of Psychopharmacology, Central Institute of Mental Health, Medical Faculty Mannheim, Heidelberg University, 68159 Mannheim, Germany
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  • ORCID record for Rainer Spanagel
  • For correspondence: rainer.spanagel@zi-mannheim.de
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Keywords

  • molecular modeling
  • rat mutagenesis
  • in vivo microdialysis
  • RDoC matrix
  • mGluR2/3 antagonist LY341495

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RESEARCH ARTICLE
Towards trans-diagnostic mechanisms in psychiatry: neurobehavioral profile of rats with a loss-of-function point mutation in the dopamine transporter gene
Valentina Vengeliene, Anton Bespalov, Martin Roßmanith, Sandra Horschitz, Stefan Berger, Ana L. Relo, Hamid R. Noori, Peggy Schneider, Thomas Enkel, Dusan Bartsch, Miriam Schneider, Berthold Behl, Anita C. Hansson, Patrick Schloss, Rainer Spanagel
Disease Models & Mechanisms 2017 10: 451-461; doi: 10.1242/dmm.027623
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RESEARCH ARTICLE
Towards trans-diagnostic mechanisms in psychiatry: neurobehavioral profile of rats with a loss-of-function point mutation in the dopamine transporter gene
Valentina Vengeliene, Anton Bespalov, Martin Roßmanith, Sandra Horschitz, Stefan Berger, Ana L. Relo, Hamid R. Noori, Peggy Schneider, Thomas Enkel, Dusan Bartsch, Miriam Schneider, Berthold Behl, Anita C. Hansson, Patrick Schloss, Rainer Spanagel
Disease Models & Mechanisms 2017 10: 451-461; doi: 10.1242/dmm.027623

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