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DMM and the Board of The Company of Biologists are delighted to announce the appointment of Professor Elizabeth Patton (Edinburgh, UK) as the new Editor-in-Chief of DMM.
Find out more about the appointment. 

Disease Models & Mechanisms: 13 (12)

Archive

Disease Models & Mechanisms (DMM) is an Open Access biomedical research journal focusing on the use of model systems to better understand, diagnose and treat human disease.

The primary aim of DMM is to promote human health by inspiring collaboration between basic and clinical researchers in translational science. The journal is committed to presenting rigorously peer-reviewed research that has significant translational impact. The interdisciplinary nature of DMM means that a diverse range of diseases, approaches and models fall within its broad scope. DMM is guided by an international team of expert research-active Editors, led by Editor-in-Chief Elizabeth Patton and Deputy Editor-in-Chief Elaine Mardis, and supported by an outstanding Editorial Advisory Board.

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  • Accepted manuscripts
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  • Open Access

    Neural crest-specific deletion of Bmp7 leads to midfacial hypoplasia, nasal airway obstruction, and disordered breathing modelling Obstructive Sleep Apnea

    Pranidhi Baddam, Vivian Biancardi, Daniela M. Roth, Farah Eaton, Claudine Thereza-Bussolaro, Rupasri Mandal, David S. Wishart, Amy Barr, Joanna MacLean, Carlos Flores-Mir, Silvia Pagliardini, Daniel Graf
    PDF
  • Open Access

    Inducible expression of human C9ORF72 36x G4C2 hexanucleotide repeats is sufficient to cause RAN translation and rapid muscular atrophy in mice

    F. W. Riemslagh, E. C. van der Toorn, R. F. M. Verhagen, A. Maas, L. W. J. Bosman, R. K. Hukema, R. Willemsen
    PDF
  • Open Access

    A muscle growth promoting treatment based on the attenuation of activin/myostatin signalling in young mice results in long-term testicular abnormalities

    Danielle Vaughan, Robert Mitchell, Oliver Kretz, David Chambers, Maciej Lalowski, Helge Amthor, Olli Ritvos, Arja Pasternack, Antonios Matsakas, Sakthivel Vaiyapuri, Tobias B. Huber, Bernd Denecke, Abir Mukherjee, Darius Widera, Ketan Patel
    PDF
  • Open Access

    TDP-43 mislocalization drives neurofilament changes in a novel model of TDP-43 proteinopathy

    Rachel Atkinson, Jacqueline Leung, James Bender, Matthew Kirkcaldie, James Vickers, Anna King
    PDF
  • Open Access

    Interpreting the pathogenicity of Joubert Syndrome missense variants in Caenorhabditis elegans

    Karen I. Lange, Sofia Tsiropoulou, Katarzyna Kucharska, Oliver E. Blacque
    PDF
See more accepted manuscripts...

Editor's choice

Silke Sperling and colleagues used Drosophila to identify MYOM2 as a candidate gene in congenital heart malformations.

Learn more about the first authors of this paper, Emilie Auxerre-Plantié and Tanja Nielsen, in their First Person interview.

New reviews from DMM

Pulmonary neuroendocrine cells are a rare, multi-functional epithelial cell population. Learn more about their biology and pathology in a new review by Mitsuru Morimoto and colleagues.

We also highlight an article by the Hecksher-Sørensen group describing a new 3D imaging platform for tracking β-cell dynamics and leukocyte infiltration in the murine diabetic pancreas.

Call for Papers – The RAS Pathway

Highlighted articles

  • Myh6-driven Cre recombinase activates the DNA...
    Xinrui Wang, Amelia Lauth, Tina C. Wan, John W. Lough, John A. Auchampach
  • Identification of MYOM2 as a candidate gene in...
    Emilie Auxerre-Plantié, Tanja Nielsen, Marcel Grunert, Olga Olejniczak, Andreas Perrot, Cemil Özcelik, Dennis Harries, Faramarz Matinmehr, Cristobal Dos Remedios, Christian Mühlfeld, Theresia Kraft, Rolf Bodmer, Georg Vogler, Silke R. Sperling
  • 3D quantification of changes in pancreatic islets in mouse models of diabetes type I and II
    Urmas Roostalu, Jacob Lercke Skytte, Casper Gravesen Salinas, Thomas Klein, Niels Vrang, Jacob Jelsing, Jacob Hecksher-Sørensen
  • Modulating the endoplasmic reticulum stress response...
    James J. Doyle, Celine Vrancx, Claudia Maios, Audrey Labarre, Shunmoogum A. Patten, J. Alex Parker
  • Deletion of Yy1 in mouse lung epithelium unveils...
    Kim Landry-Truchon, Nicolas Houde, Mickaël Lhuillier, Louis Charron, Alice Hadchouel, Christophe Delacourt, William D. Foulkes, Louise Galmiche-Rolland, Lucie Jeannotte
  • Predicting experimental success: a retrospective case-control study using the rat intraluminal...
    Lisa Liebenstund, Mark Coburn, Christina Fitzner, Antje Willuweit, Karl-Josef Langen, Jingjin Liu, Michael Veldeman, Anke Höllig
  • Alcoholic hepatitis and metabolic disturbance in female...
    Lozan Sheriff, Reenam S. Khan, Raquel Saborano, Richard Wilkin, Nguyet-Thin Luu, Ulrich L. Gunther, Stefan G. Hubscher, Philip N. Newsome, Patricia F. Lalor
  • Impaired muscle morphology in a Drosophila model...
    Martin Dahl-Halvarsson, Montse Olive, Malgorzata Pokrzywa, Michaela Norum, Katarina Ejeskär, Homa Tajsharghi

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Development Journal of Cell Science Journal of Experimental Biology Disease Models & Mechanisms Biology Open

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