Disease Models & Mechanisms (DMM) is an online Open Access journal focusing on the use of model systems to better understand, diagnose and treat human disease.
The primary aim of DMM is to promote human health by inspiring collaboration between basic and clinical researchers in translational science. The journal is committed to presenting rigorously peer-reviewed research that has significant translational impact. The interdisciplinary nature of DMM means that a diverse range of diseases, approaches and models fall within its broad scope. DMM is guided by an international team of expert research-active Editors, led by Monica Justice and Ross Cagan, and supported by an outstanding Editorial Advisory Board.
Our Special Issue - A Guide to Using Neuromuscular Disease Models for Basic and Preclinical Studies - is now open. Click here to read the latest papers.
Editor's choice
A new Resource by Dipen Maru's group describes a new patient-derived orthotopic xenograft model of gastroesophageal cancer that maintains the morphological and molecular characteristics of the source tumour.
Also in this issue, Lehner and colleagues identify a macrophage-like CX3CL1/CX3CR1-expressing population of cells within the healthy tendon that have a surveillance function.
Recent highlights
Real-time genomic surveillance, combined with in-depth exploration of the Plasmodium resistome, provides new hope for malaria elimination, discuss Thanat Chokajoorn and colleagues.
We also highlight a Review by Penney Gilbert's group that outlines our current understanding of core myopathy pathomechanisms and the available model systems.
News from DMM
DMM is excited to be an affiliate journal for Review Commons, the ASAPbio/EMBO platform for high-quality journal-independent peer-review in the life sciences, which went live on 09 December.
DMM has a new partnership with Publons, part of the Web of Science Group (a Clarivate Analytics company). Publons gives reviewers formal recognition of their peer review contributions using the Reviewer Recognition Service.
Planning your 2020 diary? Make sure you note our meeting grant deadlines. The Company of Biologists has a fabulous line up of Workshops scheduled for 2020, including one organised by DMM Editor Liz Patton, with funded places available for early-career researchers. There are also larger Journal Meetings from DMM’s sister journals Development, Journal of Cell Science and Journal of Experimental Biology.
Highlighted articles
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Omkara Lakshmi Veeranki, Zhimin Tong, Alicia Mejia, Anuj Verma, Riham Katkhuda, Roland Bassett, Tae-Beom Kim, Jing Wang, Wenhua Lang, Barbara Mino, Luisa Solis, Charles Kingsley, William Norton, Ramesh Tailor, Ji Yuan Wu, Sunil Krishnan, Steven H. Lin, Mariela Blum, Wayne Hofstetter, Jaffer Ajani, Scott Kopetz, Dipen Maru
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Yong Chen, Yuhki Koike, Lijun Chi, Abdalla Ahmed, Hiromu Miyake, Bo Li, Carol Lee, Paul Delgado-Olguín, Agostino Pierro
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Christine Lehner, Gabriel Spitzer, Renate Gehwolf, Andrea Wagner, Nadja Weissenbacher, Christian Deininger, Katja Emmanuel, Florian Wichlas, Herbert Tempfer, Andreas Traweger
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Rajni Vaid Puri, Sireesha Yerrathota, Trisha Home, Jessica Y. Idowu, V. Praveen Chakravarthi, Christopher J. Ward, Pravin C. Singhal, Gregory B. Vanden Heuvel, Timothy A. Fields, Madhulika Sharma
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Zhaoyang Liu, Janani Ramachandran, Steven A. Vokes, Ryan S. Gray
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Alberto Rissone, Erin Jimenez, Kevin Bishop, Blake Carrington, Claire Slevin, Stephen M. Wincovitch, Raman Sood, Fabio Candotti, Shawn M. Burgess