Skip to main content
Advertisement

Main menu

  • Home
  • Articles
    • Accepted manuscripts
    • Issue in progress
    • Latest complete issue
    • Issue archive
    • Archive by article type
    • Subject collections
    • Interviews
    • Sign up for alerts
  • About us
    • About DMM
    • Editors and Board
    • Editor biographies
    • Travelling Fellowships
    • Grants and funding
    • Workshops and Meetings
    • The Company of Biologists
    • Journal news
  • For authors
    • Submit a manuscript
    • Aims and scope
    • Presubmission enquiries
    • Article types
    • Manuscript preparation
    • Cover suggestions
    • Editorial process
    • Promoting your paper
    • Open Access
    • Outstanding paper prize
    • Biology Open transfer
  • Journal info
    • Journal policies
    • Rights and permissions
    • Media policies
    • Reviewer guide
    • Sign up for alerts
  • Contact
    • Contact DMM
    • Advertising
    • Feedback
  • COB
    • About The Company of Biologists
    • Development
    • Journal of Cell Science
    • Journal of Experimental Biology
    • Disease Models & Mechanisms
    • Biology Open

User menu

  • Log in

Search

  • Advanced search
Disease Models & Mechanisms
  • COB
    • About The Company of Biologists
    • Development
    • Journal of Cell Science
    • Journal of Experimental Biology
    • Disease Models & Mechanisms
    • Biology Open

supporting biologistsinspiring biology

Disease Models & Mechanisms

Advanced search

RSS   Twitter   Facebook   YouTube

  • Home
  • Articles
    • Accepted manuscripts
    • Issue in progress
    • Latest complete issue
    • Issue archive
    • Archive by article type
    • Subject collections
    • Interviews
    • Sign up for alerts
  • About us
    • About DMM
    • Editors and Board
    • Editor biographies
    • Travelling Fellowships
    • Grants and funding
    • Workshops and Meetings
    • The Company of Biologists
    • Journal news
  • For authors
    • Submit a manuscript
    • Aims and scope
    • Presubmission enquiries
    • Article types
    • Manuscript preparation
    • Cover suggestions
    • Editorial process
    • Promoting your paper
    • Open Access
    • Outstanding paper prize
    • Biology Open transfer
  • Journal info
    • Journal policies
    • Rights and permissions
    • Media policies
    • Reviewer guide
    • Sign up for alerts
  • Contact
    • Contact DMM
    • Advertising
    • Feedback
Research Article
A zebrafish model of manganism reveals reversible and treatable symptoms that are independent of neurotoxicity
Subha Bakthavatsalam, Shreya Das Sharma, Mahendra Sonawane, Vatsala Thirumalai, Ankona Datta
Disease Models & Mechanisms 2014 7: 1239-1251; doi: 10.1242/dmm.016683
Subha Bakthavatsalam
Department of Chemical Sciences, Tata Institute of Fundamental Research, 1 Homi Bhabha Road, Colaba, Mumbai-400005, India.
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Shreya Das Sharma
National Centre for Biological Sciences, Tata Institute of Fundamental Research, Bellary Road, Bangalore-560065, India.
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Mahendra Sonawane
Department of Biological Sciences, Tata Institute of Fundamental Research, 1 Homi Bhabha Road, Colaba, Mumbai-400005, India.
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Vatsala Thirumalai
National Centre for Biological Sciences, Tata Institute of Fundamental Research, Bellary Road, Bangalore-560065, India.
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Ankona Datta
Department of Chemical Sciences, Tata Institute of Fundamental Research, 1 Homi Bhabha Road, Colaba, Mumbai-400005, India.
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
  • Article
  • Figures & tables
  • Supp info
  • Info & metrics
  • PDF + SI
  • PDF
Loading

Article Information

vol. 7 no. 11, 1239-1251

DOI 
https://doi.org/10.1242/dmm.016683
PubMed 
25261567

Published By 
The Company of Biologists Ltd
Print ISSN 
1754-8403
Online ISSN 
1754-8411
History 
  • Received April 24, 2014
  • Accepted September 23, 2014
  • Published online October 30, 2014.
Posted online 
September 26, 2014
Copyright & Usage 
© 2014. Published by The Company of Biologists Ltd This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/3.0), which permits unrestricted use, distribution and reproduction in any medium provided that the original work is properly attributed.

Article Versions

  • Previous version (September 26, 2014 - 06:50).
  • Previous version (October 2, 2014 - 08:32).
  • You are viewing the most recent version of this article.

Author Information

  1. Subha Bakthavatsalam1,
  2. Shreya Das Sharma2,
  3. Mahendra Sonawane3,
  4. Vatsala Thirumalai2,* and
  5. Ankona Datta1,*
  1. 1Department of Chemical Sciences, Tata Institute of Fundamental Research, 1 Homi Bhabha Road, Colaba, Mumbai-400005, India.
  2. 2National Centre for Biological Sciences, Tata Institute of Fundamental Research, Bellary Road, Bangalore-560065, India.
  3. 3Department of Biological Sciences, Tata Institute of Fundamental Research, 1 Homi Bhabha Road, Colaba, Mumbai-400005, India.
  1. ↵* Authors for correspondence (vatsala{at}ncbs.res.in; ankona{at}tifr.res.in)
View Abstract

Article usage

Usage statistics are calculated at the beginning of each month for the previous month.

Usage statistics: September 2014 to January 2019

AbstractFullPdf
Sep 2014141085
Oct 201444315194
Nov 20144046380
Dec 20142183982
Total 20141206117441
Jan 20159945144
Feb 2015812833
Mar 20157135167
Apr 20155834112
May 2015411037
Jun 2015522519
Jul 2015375720
Aug 2015402314
Sep 2015423637
Oct 2015272064
Nov 2015163621
Dec 2015425434
Total 2015606403702
Jan 2016413459
Feb 20162329106
Mar 2016212345
Apr 2016203743
May 2016253632
Jun 2016156144
Jul 2016145046
Aug 2016174649
Sep 2016305142
Oct 2016186450
Nov 2016255750
Dec 2016175030
Total 2016266538596
Jan 2017134116
Feb 201735322
Mar 2017136140
Apr 2017126530
May 2017136719
Jun 2017104121
Jul 201787336
Aug 201735833
Sep 201736136
Oct 201765533
Nov 201797142
Dec 201735339
Total 201796699367
Jan 2018623972
Feb 201895840
Mar 2018116854
Apr 201836846
May 201846048
Jun 201835437
Jul 201875141
Aug 201883735
Sep 2018414528
Oct 2018129657
Nov 20181413355
Dec 2018713834
Total 2018881147547
Jan 20191716346
Total 20191716346
Total227930672699

Statistics from Altmetric.com

Previous ArticleNext Article
Back to top
Previous ArticleNext Article

This Issue

RSSRSS

Keywords

  • Zebrafish
  • Manganism
  • Mechanotransduction
  • Fictive motor patterns
  • Dopaminergic neurons

 Download PDF

Email

Thank you for your interest in spreading the word on Disease Models & Mechanisms.

NOTE: We only request your email address so that the person you are recommending the page to knows that you wanted them to see it, and that it is not junk mail. We do not capture any email address.

Enter multiple addresses on separate lines or separate them with commas.
A zebrafish model of manganism reveals reversible and treatable symptoms that are independent of neurotoxicity
(Your Name) has sent you a message from Disease Models & Mechanisms
(Your Name) thought you would like to see the Disease Models & Mechanisms web site.
Share
Research Article
A zebrafish model of manganism reveals reversible and treatable symptoms that are independent of neurotoxicity
Subha Bakthavatsalam, Shreya Das Sharma, Mahendra Sonawane, Vatsala Thirumalai, Ankona Datta
Disease Models & Mechanisms 2014 7: 1239-1251; doi: 10.1242/dmm.016683
del.icio.us logo Digg logo Reddit logo Twitter logo CiteULike logo Facebook logo Google logo Mendeley logo
Citation Tools
Research Article
A zebrafish model of manganism reveals reversible and treatable symptoms that are independent of neurotoxicity
Subha Bakthavatsalam, Shreya Das Sharma, Mahendra Sonawane, Vatsala Thirumalai, Ankona Datta
Disease Models & Mechanisms 2014 7: 1239-1251; doi: 10.1242/dmm.016683

Citation Manager Formats

  • BibTeX
  • Bookends
  • EasyBib
  • EndNote (tagged)
  • EndNote 8 (xml)
  • Medlars
  • Mendeley
  • Papers
  • RefWorks Tagged
  • Ref Manager
  • RIS
  • Zotero
Alerts

Please log in to add an alert for this article.

Sign in to email alerts with your email address

Article navigation

  • Top
  • Article
    • Abstract
    • INTRODUCTION
    • RESULTS
    • DISCUSSION
    • MATERIALS AND METHODS
    • Acknowledgements
    • Footnotes
    • References
  • Figures & tables
  • Supp info
  • Info & metrics
  • PDF + SI
  • PDF

Related articles

Cited by...

More in this TOC section

  • ApoE-associated modulation of neuroprotection from Aβ-mediated neurodegeneration in transgenic Caenorhabditis elegans
  • Reverse genetic screen reveals that Il34 facilitates yolk sac macrophage distribution and seeding of the brain
  • Early detection of pre-malignant lesions in a KRASG12D-driven mouse lung cancer model by monitoring circulating free DNA
Show more RESEARCH ARTICLE

Similar articles

Subject collections

  • Zebrafish as a Disease Model

Other journals from The Company of Biologists

Development

Journal of Cell Science

Journal of Experimental Biology

Biology Open

Advertisement

Editor’s choice – The ubiquitin ligase HECTD1 promotes retinoic acid signaling required for development of the aortic arch

From Fig 4: Activation of a RARE transcriptional reporter is reduced in Hectd1opm mutants

This month’s Editor’s choice is from Irene Zohn's group. They identify the ubiquitin ligase HECTD1 as a novel modulator of retinoic acid signalling, providing a model for the complex interactions in aortic arch development.  


At a Glance - Generating mouse models for biomedical research: technological advances

Extract from poster

Newer molecular technologies to precisely and efficiently manipulate the mammalian genome are enabling the production of more scientifically valuable animal models, show Channabasavaiah Gurumurthy and Kent Lloyd in this poster.


Review - Transgenic and physiological mouse models give insights into different aspects of amyotrophic lateral sclerosis

Hand holding lab mouse

In this Review Abraham Acevedo-Arozena and team compare two key types of amyotrophic lateral sclerosis (ALS) mouse models: transgenic mice and those that express genes at physiological levels.


First Person interview

Piotr Soczewka

Have you seen our interviews with the early-career first authors of our papers? The authors talk about their work in and out of the lab, the journeys that led them to where they are now and the scientists who inspired them along the way. Recently, we caught up with Piotr Soczewka.


Call for papers – A guide to using neuromuscular disease models for basic and preclinical studies

Call for papers – A guide to using neuromuscular disease models for basic and preclinical studies

We invite you to submit original research for a Special Collection focused on neuromuscular disease models, edited by Annemieke Aartsma-Rus, James Dowling and Maaike van Putten. The collection will showcase studies on the dysregulation of pathways, disease progression, approaches to treat and modify disease course in animal models, technologies for studying muscle pathophysiology and regeneration, and advances in the development of suitable in vitro and in vivo models. Submission deadline: 3 June 2019.


Why should you publish your next paper in DMM?

DMM aims to promote human health by encouraging collaboration between basic and clinical researchers, covering a diverse range of diseases, approaches and models. Our Editors are all active researchers in the field – your peers, colleagues and mentors, who know how much work has gone into every paper. DMM offers format-free submission and accepts peer review reports from other journals, making submission as easy as possible for our authors. Send us your next great paper – publish with us and you'll be in good company.


preLights - Mechanical stretch kills transformed cancer cells

preLighter Joseph Thottacherry

Joseph Thottacherry highlights a recent preprint from Michael Sheetz and colleagues, who test the importance of forces in selective apoptosis of cancer cells and the mechanisms regulating these. They find cancer cells are extremely sensitive to mechanoptosis.

Articles

  • Accepted manuscripts
  • Issue in progress
  • Latest complete issue
  • Issue archive
  • Archive by article type
  • Subject collections
  • Interviews
  • Sign up for alerts

About us

  • About DMM
  • Editors and Board
  • Editor biographies
  • Travelling Fellowships
  • Grants and funding
  • Workshops and Meetings
  • The Company of Biologists

For Authors

  • Submit a manuscript
  • Aims and scope
  • Presubmission enquiries
  • Article types
  • Manuscript preparation
  • Cover suggestions
  • Editorial process
  • Promoting your paper
  • Open Access
  • Biology Open transfer

Journal Info

  • Journal policies
  • Rights and permissions
  • Media policies
  • Reviewer guide
  • Sign up for alerts

Contact

  • Contact DMM
  • Advertising
  • Feedback

Twitter   YouTube   LinkedIn

© 2019   The Company of Biologists Ltd   Registered Charity 277992