Other journals from The Company of Biologists
From single-celled organisms to patient-derived models, cancer to neurodegeneration, Disease Models & Mechanisms publishes the best original research and resources that focus on the use of model systems to better understand, diagnose and treat human disease. Submit your paper here.
What questions you should be asking yourself before you start screening for drugs using model systems? Read the editorial from our Senior Editor Ross Cagan to avoid the common pitfalls of drug discovery and development.
In this month’s highlighted paper, Kurata and colleagues explain how Drosophila larvae represent a useful model of the infectious inflammation and sterilely induced humoral innate responses that underlie disorders associated with chronic inflammation.
Multidisciplinary researcher Blanca Figuerola is fascinated by the chemical ecology of Antarctic bryozoans, so she applied for a Travelling Fellowship from Disease Models & Mechanisms to visit Angelo Fontan’s lab at the ICB in Italy. There, she learned new techniques to help her research into the specific compounds that give bryozoans their antibacterial and haemolytic properties. Read more on her story here.
Where could your research take you? Join Blanca and the 17 early career scientists who were awarded Travelling Fellowships from Disease Models & Mechanisms in 2016. Apply now!
Yang et al. present a phenotype-based chemical screen in zebrafish that identifies miconazole as a novel hemorrhagic suppressor. Miconazole inhibits vessel rupture and hemorrhages by decreasing pErk and MMP9 in zebrafish and rats.