Subject collection: Mouse as a Disease Model
- CLARITY and PACT-based imaging of adult zebrafish and mouse for whole-animal analysis of infections
Summary: The authors apply the CLARITY and PACT techniques to image infectious structures located deep within whole adult zebrafish and mouse organs, enabling visualization of mycobacterial granulomas and host response without sectioning.
- A gene expression resource generated by genome-wide lacZ profiling in the mouse
Editor's Choice: The report presents an open-access adult mouse expression resource, in which the expression profile of 424 genes has been assessed in up to 47 different organs, tissues and sub-structures using a lacZ reporter gene.
- A simple method for in vivo labelling of infiltrating leukocytes in the mouse retina using indocyanine green dye
Summary: We show here that peripheral leukocytes can be labelled with ICG in vivo and then directly imaged as they invade the retina after inflammatory stimuli.